Canlyniadau Chwilio - Perry, Jason

The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins gan Perry, Jason

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A Mutation in the Anticodon of a Single tRNA(ala) Is Sufficient to Confer Auxin Resistance in Arabidopsis gan Perry, Jason, Dai, Xinhua, Zhao, Yunde

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Effects of transition metals on nitric oxide synthase catalysis gan Perry, Jason M., Marletta, Michael A.

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Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling gan Perry, Jason, Kleckner, Nancy, Börner, G. Valentin

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1646. Combined Resistance Analyses From Phase 2b Studies of Presatovir Treatment in RSV-Infected Adults gan Porter, Danielle, Guo, Ying, Perry, Jason, Gossage, David, Watkins, Timothy, Chien, Jason, Jordan, Robert

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Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resist... gan Martin, Ross, Li, Jiani, Parvangada, Aiyappa, Perry, Jason, Cihlar, Tomas, Mo, Hongmei, Porter, Danielle, Svarovskaia, Evguenia

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An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15 gan Perry, Jason K., Appleby, Todd C., Bilello, John P., Feng, Joy Y., Schmitz, Uli, Campbell, Elizabeth A.

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Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus gan Porter, Danielle P., Guo, Ying, Perry, Jason, Gossage, David L., Watkins, Timothy R., Chien, Jason W., Jordan, Robert

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency gan Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action gan Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Correction: Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action gan Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocincova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir gan Gordon, Calvin J., Lee, Hery W., Tchesnokov, Egor P., Perry, Jason K., Feng, Joy Y., Bilello, John P., Porter, Danielle P., Götte, Matthias

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Optimized high-throughput screen for Hepatitis C virus translation inhibitors gan Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung

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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex gan Chen, James, Wang, Qi, Malone, Brandon, Llewellyn, Eliza, Pechersky, Yakov, Maruthi, Kashyap, Eng, Ed T., Perry, Jason K., Campbell, Elizabeth A., Shaw, David E., Darst, Seth A.

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Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler gan Perry, Jason, Trautman, Brian, Takher‐Smith, Joe, Kramer, Steve, Kane, Katie, Silverman, Michael, Tan, Lisa, Haughie, Scott, Richter, Wolfram, Kirkov, Valentin, Arsova, Sacha, Ward, Jonathan, Hava, David L.

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In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance gan Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy

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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors gan Lansdon, Eric B., Liu, Qi, Leavitt, Stephanie A., Balakrishnan, Mini, Perry, Jason K., Lancaster-Moyer, Candra, Kutty, Nilima, Liu, Xiaohong, Squires, Neil H., Watkins, William J., Kirschberg, Thorsten A.

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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors gan Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman

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A New Natural Defense Against Airborne Pathogens gan Edwards, David, Hickey, Anthony, Batycky, Richard, Griel, Lester, Lipp, Michael, Dehaan, Wes, Clarke, Robert, Hava, David, Perry, Jason, Laurenzi, Brendan, Curran, Aidan K., Beddingfield, Brandon J., Roy, Chad J., Devlin, Tom, Langer, Robert

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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics gan Hava, David L., Tan, Lisa, Johnson, Patrick, Curran, Aidan K., Perry, Jason, Kramer, Steve, Kane, Katie, Bedwell, Pauline, Layton, Gary, Swann, Clarie, Henderson, Dennis, Khan, Naimat, Connor, Lucy, McKenzie, Litza, Singh, Dave, Roach, James

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