Resultats de la cerca - Perry, Jason

The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins per Perry, Jason

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A Mutation in the Anticodon of a Single tRNA(ala) Is Sufficient to Confer Auxin Resistance in Arabidopsis per Perry, Jason, Dai, Xinhua, Zhao, Yunde

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Effects of transition metals on nitric oxide synthase catalysis per Perry, Jason M., Marletta, Michael A.

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Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling per Perry, Jason, Kleckner, Nancy, Börner, G. Valentin

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1646. Combined Resistance Analyses From Phase 2b Studies of Presatovir Treatment in RSV-Infected Adults per Porter, Danielle, Guo, Ying, Perry, Jason, Gossage, David, Watkins, Timothy, Chien, Jason, Jordan, Robert

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Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resist... per Martin, Ross, Li, Jiani, Parvangada, Aiyappa, Perry, Jason, Cihlar, Tomas, Mo, Hongmei, Porter, Danielle, Svarovskaia, Evguenia

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An atomistic model of the coronavirus replication-transcription complex as a hexamer assembled around nsp15 per Perry, Jason K., Appleby, Todd C., Bilello, John P., Feng, Joy Y., Schmitz, Uli, Campbell, Elizabeth A.

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Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus per Porter, Danielle P., Guo, Ying, Perry, Jason, Gossage, David L., Watkins, Timothy R., Chien, Jason W., Jordan, Robert

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency per Gordon, Calvin J., Tchesnokov, Egor P., Woolner, Emma, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action per Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocinkova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Correction: Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action per Tchesnokov, Egor P., Gordon, Calvin J., Woolner, Emma, Kocincova, Dana, Perry, Jason K., Feng, Joy Y., Porter, Danielle P., Götte, Matthias

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Efficient incorporation and template-dependent polymerase inhibition are major determinants for the broad-spectrum antiviral activity of remdesivir per Gordon, Calvin J., Lee, Hery W., Tchesnokov, Egor P., Perry, Jason K., Feng, Joy Y., Bilello, John P., Porter, Danielle P., Götte, Matthias

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Optimized high-throughput screen for Hepatitis C virus translation inhibitors per Berry, Katherine E., Peng, Betty, Koditek, David, Beeman, Douglas, Pagratis, Nikos, Perry, Jason K., Parrish, Jay, Zhong, Weidong, Doudna, Jennifer A., Shih, I-hung

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Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex per Chen, James, Wang, Qi, Malone, Brandon, Llewellyn, Eliza, Pechersky, Yakov, Maruthi, Kashyap, Eng, Ed T., Perry, Jason K., Campbell, Elizabeth A., Shaw, David E., Darst, Seth A.

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Particle size and gastrointestinal absorption influence tiotropium pharmacokinetics: a pilot bioequivalence study of PUR0200 and Spiriva HandiHaler per Perry, Jason, Trautman, Brian, Takher‐Smith, Joe, Kramer, Steve, Kane, Katie, Silverman, Michael, Tan, Lisa, Haughie, Scott, Richter, Wolfram, Kirkov, Valentin, Arsova, Sacha, Ward, Jonathan, Hava, David L.

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In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance per Checkmahomed, Liva, Carbonneau, Julie, Du Pont, Venice, Riola, Nicholas C., Perry, Jason K., Li, Jiani, Paré, Bastien, Simpson, Shawn M., Smith, Martin A., Porter, Danielle P., Boivin, Guy

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Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors per Lansdon, Eric B., Liu, Qi, Leavitt, Stephanie A., Balakrishnan, Mini, Perry, Jason K., Lancaster-Moyer, Candra, Kutty, Nilima, Liu, Xiaohong, Squires, Neil H., Watkins, William J., Kirschberg, Thorsten A.

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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors per Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman

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A New Natural Defense Against Airborne Pathogens per Edwards, David, Hickey, Anthony, Batycky, Richard, Griel, Lester, Lipp, Michael, Dehaan, Wes, Clarke, Robert, Hava, David, Perry, Jason, Laurenzi, Brendan, Curran, Aidan K., Beddingfield, Brandon J., Roy, Chad J., Devlin, Tom, Langer, Robert

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A phase 1/1b study of PUR1900, an inhaled formulation of itraconazole, in healthy volunteers and asthmatics to study safety, tolerability and pharmacokinetics per Hava, David L., Tan, Lisa, Johnson, Patrick, Curran, Aidan K., Perry, Jason, Kramer, Steve, Kane, Katie, Bedwell, Pauline, Layton, Gary, Swann, Clarie, Henderson, Dennis, Khan, Naimat, Connor, Lucy, McKenzie, Litza, Singh, Dave, Roach, James

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