Søgeresultater - Pengrong Yan

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  1. 1
    Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

    Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK) af Guoliang Qing, Pengrong Yan, Gutian Xiao

    Udgivet 2006
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  2. 2
    Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation

    Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation af Guoliang Qing, Pengrong Yan, Zhaoxia Qu, Hudan Liu, Gutian Xiao

    Udgivet 2007
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  3. 3
    Epigenetic Repression of PDZ-LIM Domain-containing Protein 2

    Epigenetic Repression of PDZ-LIM Domain-containing Protein 2 af Zhaoxia Qu, Jing Fu, Pengrong Yan, Jing Hu, Shi‐Yuan Cheng, Gutian Xiao

    Udgivet 2010
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  4. 4
    PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

    PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation af Pengrong Yan, Jing Fu, Zhaoxia Qu, Shirong Li, Takashi Tanaka, Michael J. Grusby, Gutian Xiao

    Udgivet 2009
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  5. 5
    Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

    Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance af Fan Sun, Liwen Li, Pengrong Yan, Jingjiao Zhou, Steven D. Shapiro, Gutian Xiao, Zhaoxia Qu

    Udgivet 2019
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  6. 6
    DNA Methylation–Dependent Repression of PDZ-LIM Domain–Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target

    DNA Methylation–Dependent Repression of PDZ-LIM Domain–Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target af Zhaoxia Qu, Pengrong Yan, Jing Fu, Jing Jiang, Michael J. Grusby, Thomas E. Smithgall, Gutian Xiao

    Udgivet 2010
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  7. 7
    The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

    The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis af Jing Fu, Zhaoxia Qu, Pengrong Yan, Chie Ishikawa, Rami I. Aqeilan, Arnold B. Rabson, Gutian Xiao

    Udgivet 2010
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  8. 8
    How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

    How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view af Matteo Castelli, Pengrong Yan, Anna Rodina, Chander Singh Digwal, Palak Panchal, Gabriela Chiosis, Elisabetta Moroni, Giorgio Colombo

    Udgivet 2023
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  9. 9
    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

    Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 af Pallav D. Patel, Pengrong Yan, Paul M. Seidler, Hardik J. Patel, Weilin Sun, Chenghua Yang, Nanette S. Que, Tony Taldone, Paola Finotti, Ralph A. Stephani, D.T. Gewirth, Gabriela Chiosis

    Udgivet 2013
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  10. 10
    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond

    A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond af Tony Taldone, Tai Wang, Anna Rodina, Nagavarakishore Pillarsetty, Chander Singh Digwal, Sahil Sharma, Pengrong Yan, Suhasini Joshi, Piyusha P. Pagare, Alexander Bolaender, Gail J. Roboz, Mónica L. Guzmán, Gabriela Chiosis

    Udgivet 2019
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  11. 11
    Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein

    Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein af Anna Rodina, Pallav D. Patel, Yanlong Kang, Yogita Patel, Imad Baaklini, Michael Wong, Tony Taldone, Pengrong Yan, Chenghua Yang, Ronnie Maharaj, Alexander Gozman, Maulik Patel, Hardik Patel, William J. Chirico, Hediye Erdjument‐Bromage, Tanaji T. Talele, Jason C. Young, Gabriela Chiosis

    Udgivet 2013
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  12. 12
    Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

    Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94 af Hardik Patel, Pallav D. Patel, Stefan O. Ochiana, Pengrong Yan, Weilin Sun, Maulik Patel, Smit Shah, Elisa Tramentozzi, James C. Brooks, Alexander Bolaender, Liza Shrestha, Ralph A. Stephani, Paola Finotti, Cynthia A. Leifer, Zihai Li, D.T. Gewirth, Tony Taldone, Gabriela Chiosis

    Udgivet 2015
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  13. 13
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone af Pengrong Yan, Hardik J. Patel, Sahil Sharma, Adriana Corben, Tai Wang, Palak Panchal, Chenghua Yang, Weilin Sun, Thaís L.S. Araujo, Anna Rodina, Suhasini Joshi, Kenneth Robzyk, Srinivasa Gandu, Julie R. White, Elisa de Stanchina, Shanu Modi, Yelena Y. Janjigian, Elizabeth G. Hill, Bei Liu, Hediye Erdjument‐Bromage, Thomas A. Neubert, Nanette L. S. Que, Zihai Li, D.T. Gewirth, Tony Taldone, Gabriela Chiosis

    Udgivet 2020
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  14. 14
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation af Anna Rodina, Chao Xu, Chander Singh Digwal, Suhasini Joshi, Yogita Patel, Anand Ramaian Santhaseela, Sadık Bay, Swathi Merugu, Aftab Alam, Pengrong Yan, Chenghua Yang, Tanaya Roychowdhury, Palak Panchal, Liza Shrestha, Yanlong Kang, Sahil Sharma, Justina Almodovar, Adriana Corben, Mary L. Alpaugh, Shanu Modi, Mónica L. Guzmán, Teng Fei, Tony Taldone, Stephen D. Ginsberg, Hediye Erdjument‐Bromage, Thomas A. Neubert, Katia Manova‐Todorova, Meng-Fu Bryan Tsou, Jason C. Young, Tai Wang, Gabriela Chiosis

    Udgivet 2023
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  15. 15
    Paradigms for Precision Medicine in Epichaperome Cancer Therapy

    Paradigms for Precision Medicine in Epichaperome Cancer Therapy af Nagavarakishore Pillarsetty, Komal Jhaveri, Tony Taldone, Eloisi Caldas-Lopes, Blesida Punzalan, Suhasini Joshi, Alexander Bolaender, Mohammad M. Uddin, Anna Rodina, Pengrong Yan, Anson T. Ku, Thomas W. Ku, Smit Shah, Serge K. Lyashchenko, Eva Burnazi, Tai Wang, Nicolas Lecomte, Yelena Y. Janjigian, Anas Younes, Connie Lee Batlevi, Mónica L. Guzmán, Gail J. Roboz, Jacek Koziorowski, Pat Zanzonico, Mary L. Alpaugh, Adriana Corben, Shanu Modi, Larry Norton, Steven M. Larson, Jason S. Lewis, Gabriela Chiosis, John F. Gerecitano, Mark Dunphy

    Udgivet 2019
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  16. 16
    The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

    The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction af Maria Carmen Inda, Suhasini Joshi, Tai Wang, Alexander Bolaender, Srinivasa Gandu, John Koren, Alicia Yue, Tony Taldone, Pengrong Yan, Weilin Sun, Mohammad Uddin, Palak Panchal, Matthew Riolo, Smit Shah, Afşar Barlas, Ke Xu, Lon Yin L. Chan, Alexandra Gruzinova, Sarah Kishinevsky, Lorenz Studer, Valentina Fossati, Scott Noggle, Julie R. White, Elisa de Stanchina, Sonia Sequeira, Kyle H. Anthoney, John Steele, Katia Manova‐Todorova, Sujata Patil, Mark Dunphy, Nagavarakishore Pillarsetty, Ana C. Pereira, Hediye Erdjument‐Bromage, Thomas A. Neubert, Anna Rodina, Stephen D. Ginsberg, Natalia De Marco García, Wenjie Luo, Gabriela Chiosis

    Udgivet 2020
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  17. 17
    The epichaperome is an integrated chaperome network that facilitates tumour survival

    The epichaperome is an integrated chaperome network that facilitates tumour survival af Anna Rodina, Tai Wang, Pengrong Yan, Erica DaGama Gomes, Mark Dunphy, Nagavarakishore Pillarsetty, John Koren, John F. Gerecitano, Tony Taldone, Hongliang Zong, Eloisi Caldas-Lopes, Mary L. Alpaugh, Adriana Corben, Matthew Riolo, Brad Beattie, Christina Pressl, Ioan Radu Peter, Chao Xu, Robert Trondl, Hardik J. Patel, Fumiko Shimizu, Alexander Bolaender, Chenghua Yang, Palak Panchal, Mohammad Farooq, Sarah Kishinevsky, Shanu Modi, Oscar Lin, Feixia Chu, Sujata Patil, Hediye Erdjument‐Bromage, Pat Zanzonico, Clifford A. Hudis, Lorenz Studer, Gail J. Roboz, Ethel Cesarman, Leandro Cerchietti, Ross L. Levine, Ari Melnick, Steven M. Larson, Jason S. Lewis, Mónica L. Guzmán, Gabriela Chiosis

    Udgivet 2016
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