Search Results - Paul R. Heath

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  1. 1
    The genetics of amyotrophic lateral sclerosis: current insights

    The genetics of amyotrophic lateral sclerosis: current insights by Janine Kirby, Afnan Al Sultan, Rachel Waller, Paul R. Heath

    Published 2016
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  2. 2
    Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

    Neuronal dark matter: the emerging role of microRNAs in neurodegeneration by Gerald Goodall, Paul R. Heath, Oliver Bandmann, Janine Kirby, Pamela J. Shaw

    Published 2013
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  3. 3
    Gene expression profiling in human neurodegenerative disease

    Gene expression profiling in human neurodegenerative disease by Johnathan Cooper‐Knock, Janine Kirby, Laura Ferraiuolo, Paul R. Heath, Magnus Rattray, Pamela J. Shaw

    Published 2012
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  4. 4
    Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS

    Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS by Laura Ferraiuolo, Paul R. Heath, Hazel M. Holden, Paul R. Kasher, Janine Kirby, Pamela J. Shaw

    Published 2007
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  5. 5
    Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity

    Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity by Rachel Waller, Matthew Wyles, Paul R. Heath, Mbombe Kazoka, Helen Wollff, Pamela J. Shaw, Janine Kirby

    Published 2018
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  6. 6
    Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis

    Dysregulation of astrocyte–motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis by Laura Ferraiuolo, Adrian Higginbottom, Paul R. Heath, Siân C. Barber, David Greenald, Janine Kirby, Pamela J. Shaw

    Published 2011
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  7. 7
    Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease

    Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease by Kamar E. Ameen‐Ali, Stephen B. Wharton, Julie E. Simpson, Paul R. Heath, Paul Sharp, Jason Berwick

    Published 2017
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  8. 8
    Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central role

    Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central role by Claire J. Garwood, Laura E. Ratcliffe, Julie E. Simpson, Paul R. Heath, Paul G. Ince, Stephen B. Wharton

    Published 2016
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  9. 9
    Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis

    Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis by Tatyana A. Shelkovnikova, Michail S. Kukharsky, Haiyan An, Pasquale Dimasi, Svetlana Alexeeva, Osman Shabir, Paul R. Heath, Vladimir L. Buchman

    Published 2018
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  10. 10
    Expression of p16 and p21 in the frontal association cortex of <scp>ALS</scp>/<scp>MND</scp> brains suggests neuronal cell cycle dysregulation and astrocyte senescence in early stages of the disease

    Expression of p16 and p21 in the frontal association cortex of <scp>ALS</scp>/<scp>MND</scp> brains suggests neuronal cell cycle dysregulation and astrocyte senescence in early sta... by Irina Vázquez-Villaseñor, Claire J. Garwood, Paul R. Heath, Julie E. Simpson, Paul G. Ince, Stephen B. Wharton

    Published 2019
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  11. 11
    Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

    Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro by Anjana Ajikumar, Merete Long, Paul R. Heath, Stephen B. Wharton, Paul G. Ince, Victoria Ridger, Julie E. Simpson

    Published 2019
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  12. 12
    Regulation of Neutrophil Senescence by MicroRNAs

    Regulation of Neutrophil Senescence by MicroRNAs by Jon R. Ward, Paul R. Heath, James W.F. Catto, Moira K. B. Whyte, Marta Milo, Stephen A. Renshaw

    Published 2011
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  13. 13
    Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

    Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia by Mootaz M. Salman, Philip Kitchen, M. Nicola Woodroofe, Roslyn M. Bill, Alex C. Conner, Paul R. Heath, Matthew T. Conner

    Published 2017
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  14. 14
    Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 G93A mouse model of amyotrophic lateral sclerosis

    Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 G93A mouse model of amyotrophic lateral sclerosis by David Baker, D. Blackburn, Marcus Keatinge, Dilraj Sokhi, Paulius Viskaitis, Paul R. Heath, Laura Ferraiuolo, Janine Kirby, Pamela J. Shaw

    Published 2015
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  15. 15
    Luzp4 defines a new mRNA export pathway in cancer cells

    Luzp4 defines a new mRNA export pathway in cancer cells by Nicolas Viphakone, Marcus Cumberbatch, Michaela J. Livingstone, Paul R. Heath, Mark J. Dickman, James W.F. Catto, Stuart A. Wilson

    Published 2015
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  16. 16
    The Extracellular Vesicles Proteome of Endometrial Cells Simulating the Receptive Menstrual Phase Differs from That of Endometrial Cells Simulating the Non-Receptive Menstrual Phase

    The Extracellular Vesicles Proteome of Endometrial Cells Simulating the Receptive Menstrual Phase Differs from That of Endometrial Cells Simulating the Non-Receptive Menstrual Phas... by Amber Rose Hart, Norhayati Liaqat Ali Khan, Keerthie Dissanayake, Kasun Godakumara, Aneta Andronowska, Saji Eapen, Paul R. Heath, Alireza Fazeli

    Published 2023
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  17. 17
    Alpha‐synuclein mRNA expression in oligodendrocytes in MSA

    Alpha‐synuclein mRNA expression in oligodendrocytes in MSA by Yasmine T. Asi, Julie E. Simpson, Paul R. Heath, Stephen B. Wharton, Andrew J. Lees, Tamás Révész, Henry Houlden, Janice L. Holton

    Published 2014
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  18. 18
    Analysis of the Cytosolic Proteome in a Cell Culture Model of Familial Amyotrophic Lateral Sclerosis Reveals Alterations to the Proteasome, Antioxidant Defenses, and Nitric Oxide Synthetic Pathways

    Analysis of the Cytosolic Proteome in a Cell Culture Model of Familial Amyotrophic Lateral Sclerosis Reveals Alterations to the Proteasome, Antioxidant Defenses, and Nitric Oxide S... by Simon Allen, Paul R. Heath, Janine Kirby, Stephen B. Wharton, Mark Cookson, Fiona M. Menzies, Rosamonde E. Banks, Pamela J. Shaw

    Published 2003
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  19. 19
    The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type

    The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type by Katie Richardson, Scott P. Allen, Heather Mortiboys, Andrew J. Grierson, Stephen B. Wharton, Paul G. Ince, Pamela J. Shaw, Paul R. Heath

    Published 2013
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  20. 20
    Age‐associated changes in the blood‐brain barrier: comparative studies in human and mouse

    Age‐associated changes in the blood‐brain barrier: comparative studies in human and mouse by Gerald Goodall, C. Wang, Julie E. Simpson, David Baker, David Drew, Paul R. Heath, M. Jill Saffrey, Ignacio A. Romero, Stephen B. Wharton

    Published 2017
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