Resultados de procura - Paul L. Prather

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  1. 1
    The K2/Spice Phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products

    The K2/Spice Phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products por Lisa K. Brents, Paul L. Prather

    Publicado 2013
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  2. 2
    Synthetic Pot: Not Your Grandfather’s Marijuana

    Synthetic Pot: Not Your Grandfather’s Marijuana por Benjamin M. Ford, Sherrica Tai, William E. Fantegrossi, Paul L. Prather

    Publicado 2017
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  3. 3
    Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse?

    Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? por Kathryn A. Seely, Paul L. Prather, Laura P. James, Jeffery H. Moran

    Publicado 2011
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  4. 4
    Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity?

    Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ9-THC: Mechanism underlying greater toxicity? por William E. Fantegrossi, Jeffery H. Moran, Anna Radomińska‐Pandya, Paul L. Prather

    Publicado 2013
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  5. 5
    Unifying Mechanisms of Action of the Anticancer Activities of Triterpenoids and Synthetic Analogs

    Unifying Mechanisms of Action of the Anticancer Activities of Triterpenoids and Synthetic Analogs por Stephen Safe, Paul L. Prather, Lisa K. Brents, Gayathri Chadalapaka, Indira Jutooru

    Publicado 2012
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  6. 6
    Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors

    Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors por Maheswari Rajasekaran, Lisa K. Brents, Lirit N. Franks, Jeffery H. Moran, Paul L. Prather

    Publicado 2013
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  7. 7
    Differential Drug–Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073: Implications for Drug Abuse Liability and Pain Therapy

    Differential Drug–Drug Interactions of the Synthetic Cannabinoids JWH-018 and JWH-073: Implications for Drug Abuse Liability and Pain Therapy por Lisa K. Brents, Sarah M. Zimmerman, Amanda Saffell, Paul L. Prather, William E. Fantegrossi

    Publicado 2013
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  8. 8
    The CB2 cannabinoid agonist AM‐1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset

    The CB2 cannabinoid agonist AM‐1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset por Jennifer L. Shoemaker, Kathryn A. Seely, Ronald L. Reed, John P. Crow, Paul L. Prather

    Publicado 2007
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  9. 9
    Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

    Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury por In Young Choi, Chung Ju, Angela M. A. Anthony Jalin, Da In Lee, Paul L. Prather, Won-Ki Kim

    Publicado 2013
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  10. 10
    In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: Inhalation versus intraperitoneal injection

    In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: Inhalation versus intraperitoneal injection por Ramey Marshell, Tonisha Kearney-Ramos, Lisa K. Brents, William S. Hyatt, Shidie Tai, Paul L. Prather, William E. Fantegrossi

    Publicado 2014
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  11. 11
    Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity

    Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity por Lisa K. Brents, Emily E. Reichard, Sarah M. Zimmerman, Jeffery H. Moran, William E. Fantegrossi, Paul L. Prather

    Publicado 2011
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  12. 12
    Ability of delta-opioid receptors to interact with multiple G-proteins is independent of receptor density.

    Ability of delta-opioid receptors to interact with multiple G-proteins is independent of receptor density. por Paul L. Prather, Therese M. McGinn, Laurie J. Erickson, Christopher J. Evans, Horace H. Loh, Ping‐Yee Law

    Publicado 1994
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  13. 13
    Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer

    Betulinic Acid Targets YY1 and ErbB2 through Cannabinoid Receptor-Dependent Disruption of MicroRNA-27a:ZBTB10 in Breast Cancer por Xinyi Liu, Indira Jutooru, Ping Lei, Kyounghyun Kim, Syng‐Ook Lee, Lisa K. Brents, Paul L. Prather, Stephen Safe

    Publicado 2012
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  14. 14
    Repeated administration of phytocannabinoid Δ9-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner

    Repeated administration of phytocannabinoid Δ9-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces... por Shidie Tai, William S. Hyatt, Congwei Gu, Lirit N. Franks, Tamara Vasiljevik, Lisa K. Brents, Paul L. Prather, William E. Fantegrossi

    Publicado 2015
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  15. 15
    A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors

    A Major Glucuronidated Metabolite of JWH-018 Is a Neutral Antagonist at CB1 Receptors por Kathryn A. Seely, Lisa K. Brents, Anna Radomińska‐Pandya, Gregory W. Endres, Gregory S. Keyes, Jeffery H. Moran, Paul L. Prather

    Publicado 2012
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  16. 16
    AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: Implications for opioid/cannabinoid interaction studies

    AM-251 and rimonabant act as direct antagonists at mu-opioid receptors: Implications for opioid/cannabinoid interaction studies por Kathryn A. Seely, Lisa K. Brents, Lirit N. Franks, Maheswari Rajasekaran, Sarah M. Zimmerman, William E. Fantegrossi, Paul L. Prather

    Publicado 2012
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  17. 17
    Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity

    Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial ag... por Lisa K. Brents, Anna Gallus‐Zawada, Anna Radomińska‐Pandya, Tamara Vasiljevik, Thomas E. Prisinzano, William E. Fantegrossi, Jeffery H. Moran, Paul L. Prather

    Publicado 2012
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  18. 18
    Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids

    Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids por Anna Mazur, Cheryl F. Lichti, Paul L. Prather, A. Zielińska, Stacie M. Bratton, Anna Gallus‐Zawada, Moshe Finel, Grover P. Miller, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicado 2009
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  19. 19
    Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors

    Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors por Lisa K. Brents, Fabricio Medina-Bolívar, Kathryn A. Seely, Vipin A. Nair, Stacie M. Bratton, Luis Ñopo-Olazabal, Ronak Y. Patel, Haining Liu, Robert J. Doerksen, Paul L. Prather, Anna Radomińska‐Pandya

    Publicado 2011
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  20. 20
    Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands

    Cytochrome P450-Mediated Oxidative Metabolism of Abused Synthetic Cannabinoids Found in K2/Spice: Identification of Novel Cannabinoid Receptor Ligands por Krishna C. Chimalakonda, Kathryn A. Seely, Stacie M. Bratton, Lisa K. Brents, Cindy L. Moran, Gregory W. Endres, Laura P. James, Paul F. Hollenberg, Paul L. Prather, Anna Radomińska‐Pandya, Jeffery H. Moran

    Publicado 2012
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