Søgeresultater - Paul D. Kirchhoff

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  1. 1
    Electrostatic Influence on the Kinetics of Ligand Binding to Acetylcholinesterase

    Electrostatic Influence on the Kinetics of Ligand Binding to Acetylcholinesterase af Zoran Radić, Paul D. Kirchhoff, Daniel M. Quinn, J. Andrew McCammon, Palmer Taylor

    Udgivet 1997
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  2. 2
    Inhibitors of TonB Function Identified by a High-Throughput Screen for Inhibitors of Iron Acquisition in Uropathogenic Escherichia coli CFT073

    Inhibitors of TonB Function Identified by a High-Throughput Screen for Inhibitors of Iron Acquisition in Uropathogenic Escherichia coli CFT073 af Alejandra Yep, Thomas J. McQuade, Paul D. Kirchhoff, Martha J. Larsen, Harry L. T. Mobley

    Udgivet 2014
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  3. 3
    X-ray Crystal Structures of the <i>Escherichia coli</i> RNA Polymerase in Complex with Benzoxazinorifamycins

    X-ray Crystal Structures of the <i>Escherichia coli</i> RNA Polymerase in Complex with Benzoxazinorifamycins af Vadim Molodtsov, Irosha N. Nawarathne, Nathan T. Scharf, Paul D. Kirchhoff, Hollis D. Showalter, George A. Garcia, Katsuhiko Murakami

    Udgivet 2013
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  4. 4
    Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents

    Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents af Jessica L. Bell, Andrew J. Haak, Susan M. Wade, Paul D. Kirchhoff, Richard R. Neubig, Scott D. Larsen

    Udgivet 2013
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  5. 5
    Property-based design of a glucosylceramide synthase inhibitor that reduces glucosylceramide in the brain

    Property-based design of a glucosylceramide synthase inhibitor that reduces glucosylceramide in the brain af Scott D. Larsen, Michael W. Wilson, Akira Abe, Liming Shu, Christopher H. George, Paul D. Kirchhoff, Hollis D. Showalter, Jianming Xiang, Richard F. Keep, James A. Shayman

    Udgivet 2011
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  6. 6
    Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

    Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer af Weiguo Xiang, Lijie Zhao, Xin Han, Chong Qin, Bukeyan Miao, Donna McEachern, Yu Wang, Hoda Metwally, Paul D. Kirchhoff, Lu Wang, Aleksas Matvekas, Miao He, Bo Wen, Duxin Sun, Shaomeng Wang

    Udgivet 2021
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  7. 7
    Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors

    Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors af Helen V. Waldschmidt, Kristoff T. Homan, Osvaldo Cruz-Rodríguez, M.C. Cato, Jessica Waninger‐Saroni, Kelly M. Larimore, Alessandro Cannavò, Jianliang Song, Joseph Y. Cheung, Paul D. Kirchhoff, Walter J. Koch, J.J.G. Tesmer, Scott D. Larsen

    Udgivet 2016
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  8. 8
    Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy

    Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy af Zhixiang Chen, Harshil Dhruv, Xuqing Zhang, Rohan Kalyan Rej, Longchuan Bai, Donna McEachern, Paul D. Kirchhoff, Rakesh Nagilla, Larry J. Jolivette, Cory Rice, Peter Orth, Corey O. Strickland, E. Scott Priestley, Helai P. Mohammad, Meilin Wang, Bo Wen, Duxin Sun, Zhihua Sui, Shaomeng Wang

    Udgivet 2025
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  9. 9
    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer

    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer af Weiguo Xiang, Lijie Zhao, Xin Han, Tianfeng Xu, Steven Kregel, Mi Wang, Bukeyan Miao, Chong Qin, Mingliang Wang, Donna McEachern, Jianfeng Lü, Longchuan Bai, Chao‐Yie Yang, Paul D. Kirchhoff, John Takyi‐Williams, Lu Wang, Bo Wen, Duxin Sun, Mark A. Ator, Robert McKean, Arul M. Chinnaiyan, Shaomeng Wang

    Udgivet 2023
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  10. 10
    Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

    Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance af Heng Lin, Kole Tison, Yuheng Du, Paul D. Kirchhoff, Chan Kim, Weichao Wang, Hannah Yang, Michael Pitter, Jiali Yu, Peng Liao, Jiajia Zhou, Linda Vatan, Sara Grove, Shuang Wei, Thomas M. Vigil, Yatrik M. Shah, Richard M. Mortensen, Ilona Kryczek, Lana X. Garmire, Jwala Priyadarsini Sivaccumar, Ashwin Ramesh, Ningyan Zhang, Zhiqiang An, Shaomeng Wang, Weiping Zou

    Udgivet 2024
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