Resultats de la cerca - Patrick W. Sheehan

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  1. 1
    Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease

    Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease per Jiyeon Lee, Do Eon Kim, Percy Griffin, Patrick W. Sheehan, Dong‐Hou Kim, Erik S. Musiek, Seung‐Yong Yoon

    Publicat 2019
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  2. 2
    REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis

    REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis per Percy Griffin, Patrick W. Sheehan, Julie Dimitry, Chun Guo, Michael F. Kanan, Jiyeon Lee, Jinsong Zhang, Erik S. Musiek

    Publicat 2020
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  3. 3
    Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice

    Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice per Jiyeon Lee, Julie Dimitry, Jong Hee Song, Minsoo Son, Patrick W. Sheehan, Melvin W. King, G. Travis Tabor, Young Ah Goo, Mitchell A. Lazar, Leonard Petrucelli, Erik S. Musiek

    Publicat 2023
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  4. 4
    Dural lymphatics regulate clearance of extracellular tau from the CNS

    Dural lymphatics regulate clearance of extracellular tau from the CNS per Tirth K. Patel, LeMoyne Habimana-Griffin, Xuefeng Gao, Baogang Xu, Samuel Achilefu, Kari Alitalo, Celia A. McKee, Patrick W. Sheehan, Erik S. Musiek, Chengjie Xiong, Dean W. Coble, David M. Holtzman

    Publicat 2019
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  5. 5
    Circadian clock protein Rev-erbα regulates neuroinflammation

    Circadian clock protein Rev-erbα regulates neuroinflammation per Percy Griffin, Julie Dimitry, Patrick W. Sheehan, Brian V. Lananna, Chun Guo, Michelle L. Robinette, Matthew Hayes, Michelle R. Cedeño, Collin J. Nadarajah, Lubov Ezerskiy, Marco Colonna, Jinsong Zhang, Adam Q. Bauer, Thomas P. Burris, Erik S. Musiek

    Publicat 2019
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  6. 6
    Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration

    Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration per Michael F. Kanan, Patrick W. Sheehan, Jessica N. Haines, P. Gómez, Adya Dhuler, Collin J. Nadarajah, Zachary M. Wargel, Brittany M. Freeberg, Hemanth R. Nelvagal, Mariko Izumo, Joseph S. Takahashi, Jonathan D. Cooper, Albert A. Davis, Erik S. Musiek

    Publicat 2023
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  7. 7
    ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep

    ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep per Nicholas J. Constantino, Caitlin M. Carroll, Holden C. Williams, Hemendra J. Vekaria, Carla M. Yuede, Kai Saito, Patrick W. Sheehan, James A. Snipes, Marcus E. Raichle, Erik S. Musiek, Patrick G. Sullivan, Josh M. Morganti, Lance A. Johnson, Shannon L. Macauley

    Publicat 2025
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  8. 8
    Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1

    Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1 per Brian V. Lananna, Collin J. Nadarajah, Mariko Izumo, Michelle R. Cedeño, David D. Xiong, Julie Dimitry, Chak Foon Tso, Celia A. McKee, Percy Griffin, Patrick W. Sheehan, Jeffery A. Haspel, Ben A. Barres, Shane A. Liddelow, Joseph S. Takahashi, Ilia N. Karatsoreos, Erik S. Musiek

    Publicat 2018
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  9. 9
    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

    An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology per Patrick W. Sheehan, Collin J. Nadarajah, Michael F. Kanan, Jessica N. Patterson, Brenna C. Novotny, Jennifer H. Lawrence, Melvin W. King, Logan Brase, Casey E. Inman, Carla M. Yuede, Jiyeon Lee, Tirth K. Patel, Oscar Harari, Bruno A. Benítez, Albert A. Davis, Erik S. Musiek

    Publicat 2023
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