Ngā hua rapu - Patrick McCarren

  • E whakaatu ana i te 1 - 8 hua o te 8
Whakamahine hua
  1. 1
    Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with <i>MTAP</i> Deletion

    Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with <i>MTAP</i> Deletion mā Kevin M. Cottrell, Kimberly J. Briggs, Alice Tsai, Matthew R. Tonini, Douglas A. Whittington, Shanzhong Gong, Colin Liang, Patrick McCarren, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell

    I whakaputaina 2025
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    Artigo
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  2. 2
    Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

    Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties mā Björn Over, Patrick McCarren, Per Artursson, Michael A. Foley, Fabrizio Giordanetto, Gunnar Grönberg, Constanze Hilgendorf, Maurice D. Lee, Pär Matsson, Giovanni Muncipinto, Mélanie Pellisson, Matthew W. D. Perry, Richard Svensson, Jeremy R. Duvall, Jan Kihlberg

    I whakaputaina 2014
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    Artigo
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  3. 3
    The Drug Repurposing Hub: a next-generation drug library and information resource

    The Drug Repurposing Hub: a next-generation drug library and information resource mā Steven M. Corsello, Joshua A. Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi Hirschman, Stephen Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob K. Asiedu, Rajiv Narayan, Christopher C. Mader, Aravind Subramanian, Todd R. Golub

    I whakaputaina 2017
    Whiwhi kuputuhi katoa
    Carta
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  4. 4
    A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

    A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase mā Samantha Wellington, Partha P. Nag, K. Michalska, Stephen Johnston, R. Jedrzejczak, Virendar K. Kaushik, Anne E. Clatworthy, Noman Siddiqi, Patrick McCarren, Besnik Bajrami, N.I. Maltseva, Senya Combs, Stewart L. Fisher, A. Joachimiak, Stuart L. Schreiber, Deborah T. Hung

    I whakaputaina 2017
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    Artigo
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  5. 5
    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers

    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers mā Kevin M. Cottrell, Kimberly J. Briggs, Douglas A. Whittington, Haris Jahić, Janid A. Ali, Charles B. Davis, Shanzhong Gong, Deepali Gotur, Lina Gu, Patrick McCarren, Matthew R. Tonini, Alice Tsai, Erik Wilker, Hongling Yuan, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell

    I whakaputaina 2024
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    Artigo
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  6. 6
    An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

    An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8 mā David E. Olson, Namrata D. Udeshi, Noah A. Wolfson, Carol Ann Pitcairn, Eric D. Sullivan, Jacob D. Jaffe, Tanya Svinkina, Ted Natoli, Xiaodong Lü, Joshiawa Paulk, Patrick McCarren, Florence F. Wagner, Doug Barker, Eleanor Howe, Fanny Lazzaro, Jennifer Gale, Yan-Ling Zhang, Aravind Subramanian, Carol A. Fierke, Steven A. Carr, Edward B. Holson

    I whakaputaina 2014
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    Carta
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  7. 7
    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers

    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers mā Florence F. Wagner, Yarong Zhang, Daniel M. Fass, Naima T. Joseph, Jennifer Gale, Michel Weïwer, Patrick McCarren, Stewart L. Fisher, Taner Kaya, Wen‐Ning Zhao, Surya A. Reis, Krista M. Hennig, Melvin E. Thomas, Bérénice C. Lemercier, Michael C. Lewis, Ji‐Song Guan, M. P. Moyer, Edward M. Scolnick, Stephen J. Haggarty, Li‐Huei Tsai, Edward B. Holson

    I whakaputaina 2014
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    Artigo
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  8. 8
    Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction

    Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction mā David C. McKinney, Brian J. McMillan, Matthew J. Ranaghan, Jamie A. Moroco, Merissa Brousseau, Zachary Mullin-Bernstein, Meghan O’Keefe, Patrick McCarren, Michael F. Mesleh, Kathleen M. Mulvaney, Foxy P. Robinson, Ritu Singh, Besnik Bajrami, Florence F. Wagner, Robert Hilgraf, Martin J. Drysdale, Arthur J. Campbell, Adam Skepner, David E. Timm, Dale Porter, Virendar K. Kaushik, William R. Sellers, Alessandra Ianari

    I whakaputaina 2021
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    Artigo
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