Canlyniadau Chwilio - Patrick McCarren

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Mireinio'r Canlyniadau
  1. 1
    Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with <i>MTAP</i> Deletion

    Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with <i>MTAP</i> Deletion gan Kevin M. Cottrell, Kimberly J. Briggs, Alice Tsai, Matthew R. Tonini, Douglas A. Whittington, Shanzhong Gong, Colin Liang, Patrick McCarren, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell

    Cyhoeddwyd 2025
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    Artigo
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  2. 2
    Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

    Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties gan Björn Over, Patrick McCarren, Per Artursson, Michael A. Foley, Fabrizio Giordanetto, Gunnar Grönberg, Constanze Hilgendorf, Maurice D. Lee, Pär Matsson, Giovanni Muncipinto, Mélanie Pellisson, Matthew W. D. Perry, Richard Svensson, Jeremy R. Duvall, Jan Kihlberg

    Cyhoeddwyd 2014
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    Artigo
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  3. 3
    The Drug Repurposing Hub: a next-generation drug library and information resource

    The Drug Repurposing Hub: a next-generation drug library and information resource gan Steven M. Corsello, Joshua A. Bittker, Zihan Liu, Joshua Gould, Patrick McCarren, Jodi Hirschman, Stephen Johnston, Anita Vrcic, Bang Wong, Mariya Khan, Jacob K. Asiedu, Rajiv Narayan, Christopher C. Mader, Aravind Subramanian, Todd R. Golub

    Cyhoeddwyd 2017
    Cael y testun llawn
    Carta
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  4. 4
    A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase

    A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase gan Samantha Wellington, Partha P. Nag, K. Michalska, Stephen Johnston, R. Jedrzejczak, Virendar K. Kaushik, Anne E. Clatworthy, Noman Siddiqi, Patrick McCarren, Besnik Bajrami, N.I. Maltseva, Senya Combs, Stewart L. Fisher, A. Joachimiak, Stuart L. Schreiber, Deborah T. Hung

    Cyhoeddwyd 2017
    Cael y testun llawn
    Artigo
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  5. 5
    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers

    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers gan Kevin M. Cottrell, Kimberly J. Briggs, Douglas A. Whittington, Haris Jahić, Janid A. Ali, Charles B. Davis, Shanzhong Gong, Deepali Gotur, Lina Gu, Patrick McCarren, Matthew R. Tonini, Alice Tsai, Erik Wilker, Hongling Yuan, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell

    Cyhoeddwyd 2024
    Cael y testun llawn Cael y testun llawn
    Artigo
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  6. 6
    An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

    An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8 gan David E. Olson, Namrata D. Udeshi, Noah A. Wolfson, Carol Ann Pitcairn, Eric D. Sullivan, Jacob D. Jaffe, Tanya Svinkina, Ted Natoli, Xiaodong Lü, Joshiawa Paulk, Patrick McCarren, Florence F. Wagner, Doug Barker, Eleanor Howe, Fanny Lazzaro, Jennifer Gale, Yan-Ling Zhang, Aravind Subramanian, Carol A. Fierke, Steven A. Carr, Edward B. Holson

    Cyhoeddwyd 2014
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  7. 7
    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers

    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers gan Florence F. Wagner, Yarong Zhang, Daniel M. Fass, Naima T. Joseph, Jennifer Gale, Michel Weïwer, Patrick McCarren, Stewart L. Fisher, Taner Kaya, Wen‐Ning Zhao, Surya A. Reis, Krista M. Hennig, Melvin E. Thomas, Bérénice C. Lemercier, Michael C. Lewis, Ji‐Song Guan, M. P. Moyer, Edward M. Scolnick, Stephen J. Haggarty, Li‐Huei Tsai, Edward B. Holson

    Cyhoeddwyd 2014
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    Artigo
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  8. 8
    Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction

    Discovery of a First-in-Class Inhibitor of the PRMT5–Substrate Adaptor Interaction gan David C. McKinney, Brian J. McMillan, Matthew J. Ranaghan, Jamie A. Moroco, Merissa Brousseau, Zachary Mullin-Bernstein, Meghan O’Keefe, Patrick McCarren, Michael F. Mesleh, Kathleen M. Mulvaney, Foxy P. Robinson, Ritu Singh, Besnik Bajrami, Florence F. Wagner, Robert Hilgraf, Martin J. Drysdale, Arthur J. Campbell, Adam Skepner, David E. Timm, Dale Porter, Virendar K. Kaushik, William R. Sellers, Alessandra Ianari

    Cyhoeddwyd 2021
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    Artigo
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