Resultados da pesquisa - Patrick M. Woster

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  1. 1
    Synthesis and Evaluation of Novel Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1

    Synthesis and Evaluation of Novel Cyclic Peptide Inhibitors of Lysine-Specific Demethylase 1 Por Isuru R. Kumarasinghe, Patrick M. Woster

    Publicado em 2013
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  2. 2
    Recent Advances in the Development of Polyamine Analogues as Antitumor Agents

    Recent Advances in the Development of Polyamine Analogues as Antitumor Agents Por Robert A. Casero, Patrick M. Woster

    Publicado em 2009
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  3. 3
    The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines

    The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines Por Tracy Murray Stewart, Patrick M. Woster, Robert A. Casero

    Publicado em 2013
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  4. 4
    Polyamines and cancer: implications for chemotherapy and chemoprevention

    Polyamines and cancer: implications for chemotherapy and chemoprevention Por Shannon L. Nowotarski, Patrick M. Woster, Robert A. Casero

    Publicado em 2013
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  5. 5
    Targeting polyamine metabolism for cancer therapy and prevention

    Targeting polyamine metabolism for cancer therapy and prevention Por Tracy Murray Stewart, Patrick M. Woster, Robert A. Casero

    Publicado em 2016
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  6. 6
    3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors

    3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors Por Craig J. Kutz, Steven Holshouser, Ethan A. Marrow, Patrick M. Woster

    Publicado em 2014
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  7. 7
    Polyamine catabolism and oxidative damage

    Polyamine catabolism and oxidative damage Por Tracy Murray Stewart, Tiffany T. Dunston, Patrick M. Woster, Robert A. Casero

    Publicado em 2018
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  8. 8
    The role of polyamine catabolism in polyamine analogue-induced programmed cell death

    The role of polyamine catabolism in polyamine analogue-induced programmed cell death Por Hyo Chol Ha, Patrick M. Woster, James D. Yager, Robert A. Casero

    Publicado em 1997
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  9. 9
    Structural Specificity of Polyamines and Polyamine Analogues in the Protection of DNA from Strand Breaks Induced by Reactive Oxygen Species

    Structural Specificity of Polyamines and Polyamine Analogues in the Protection of DNA from Strand Breaks Induced by Reactive Oxygen Species Por Hyo Chol Ha, James D. Yager, Patrick M. Woster, Robert A. Casero

    Publicado em 1998
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  10. 10
    Antibacterial Diamines Targeting Bacterial Membranes

    Antibacterial Diamines Targeting Bacterial Membranes Por Bo Wang, Boobalan Pachaiyappan, Jordon Gruber, Michael G. Schmidt, Yongmei Zhang, Patrick M. Woster

    Publicado em 2016
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  11. 11
    The natural polyamine spermine functions directly as a free radical scavenger

    The natural polyamine spermine functions directly as a free radical scavenger Por Hyo Chol Ha, Nilantha Sirisoma, Periannan Kuppusamy, Jay L. Zweíer, Patrick M. Woster, Robert A. Casero

    Publicado em 1998
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  12. 12
    Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

    Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells Por Qingsong Zhu, Yi Huang, Laurence J. Marton, Patrick M. Woster, Nancy E. Davidson, Robert A. Casero

    Publicado em 2011
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  13. 13
    Low Molecular Weight Amidoximes that Act as Potent Inhibitors of Lysine-Specific Demethylase 1

    Low Molecular Weight Amidoximes that Act as Potent Inhibitors of Lysine-Specific Demethylase 1 Por Stuart Hazeldine, Boobalan Pachaiyappan, Nora Steinbergs, Shannon L. Nowotarski, Allison S. Hanson, Robert A. Casero, Patrick M. Woster

    Publicado em 2012
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  14. 14
    (Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators

    (Bis)urea and (Bis)thiourea Inhibitors of Lysine-Specific Demethylase 1 as Epigenetic Modulators Por Shiv K. Sharma, Yu Wu, Nora Steinbergs, Michael Crowley, Allison S. Hanson, Robert A. Casero, Patrick M. Woster

    Publicado em 2010
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  15. 15
    A Role for Bioactivation and Covalent Binding within Epidermal Keratinocytes in Sulfonamide-Induced Cutaneous Drug Reactions

    A Role for Bioactivation and Covalent Binding within Epidermal Keratinocytes in Sulfonamide-Induced Cutaneous Drug Reactions Por Timothy P. Reilly, Lawrence H. Lash, Mark A. Doll, David W. Hein, Patrick M. Woster, Craig K. Svensson

    Publicado em 2000
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  16. 16
    Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner

    Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manne... Por Lihua Jin, Christin L. Hanigan, Yu Wu, Wei Wang, Ben Ho Park, Patrick M. Woster, Robert A. Casero

    Publicado em 2012
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  17. 17
    Discovery of Novel Alkylated (bis)Urea and (bis)Thiourea Polyamine Analogues with Potent Antimalarial Activities

    Discovery of Novel Alkylated (bis)Urea and (bis)Thiourea Polyamine Analogues with Potent Antimalarial Activities Por Bianca K. Verlinden, Jandeli Niemand, Janette Snyman, Shiv K. Sharma, Ross J. Beattie, Patrick M. Woster, Lyn‐Marié Birkholtz

    Publicado em 2011
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  18. 18
    Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

    Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes Por Yi Huang, Eriko Greene, Tracy Murray Stewart, Andrew C. Goodwin, Stephen B. Baylin, Patrick M. Woster, Robert A. Casero

    Publicado em 2007
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  19. 19
    Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice

    Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice Por Devadoss J. Samuvel, Li Li, Yasodha Krishnasamy, Mónika Göőz, Kenji Takemoto, Patrick M. Woster, John J. Lemasters, Zhi Zhong

    Publicado em 2022
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  20. 20
    Alternative Spermidine Biosynthetic Route Is Critical for Growth of Campylobacter jejuni and Is the Dominant Polyamine Pathway in Human Gut Microbiota

    Alternative Spermidine Biosynthetic Route Is Critical for Growth of Campylobacter jejuni and Is the Dominant Polyamine Pathway in Human Gut Microbiota Por Colin Hanfrey, Bruce M. Pearson, Stuart Hazeldine, Jeongmi Lee, Duncan J. H. Gaskin, Patrick M. Woster, Margaret A. Phillips, Anthony J. Michael

    Publicado em 2011
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