Rezultati - Patrick J. Grohar

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  1. 1
    Prospects and challenges for the development of new therapies for Ewing sarcoma

    Prospects and challenges for the development of new therapies for Ewing sarcoma od Patrick J. Grohar, Lee J. Helman

    Izdano 2012
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  2. 2
    Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA

    Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA od May Meroueh, Patrick J. Grohar, Jian‐Wen Qiu, John SantaLucia, Stephen A. Scaringe, Christine S. Chow

    Izdano 2000
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  3. 3
    Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth

    Dual Targeting of EWS-FLI1 Activity and the Associated DNA Damage Response with Trabectedin and SN38 Synergistically Inhibits Ewing Sarcoma Cell Growth od Patrick J. Grohar, Laure E. Segars, Choh Yeung, Yves Pommier, Maurizio D’Incalci, Arnulfo Mendoza, Lee J. Helman

    Izdano 2013
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  4. 4
    Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor

    Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor od Jenna M. Gedminas, Maggie H. Chassé, Mitchell McBrairty, Ian Beddows, Susan M. Kitchen-Goosen, Patrick J. Grohar

    Izdano 2020
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  5. 5
    Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells

    Ecteinascidin 743 Interferes with the Activity of EWS-FLI1 in Ewing Sarcoma Cells od Patrick J. Grohar, Laurie B. Griffin, Choh Yeung, Qing-Rong Chen, Yves Pommier, Chand Khanna, Javed Khan, Lee J. Helman

    Izdano 2011
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  6. 6
    A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

    A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript od Patrick J. Grohar, John Glod, Cody J. Peer, Tristan M. Sissung, Fernanda I. Arnaldez, Lauren Long, William D. Figg, Patricia Whitcomb, Lee J. Helman, Brigitte C. Widemann

    Izdano 2017
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  7. 7
    Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

    Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening od Patrick J. Grohar, Girma M. Woldemichael, Laurie B. Griffin, Arnulfo Mendoza, Qing-Rong Chen, Choh Yeung, Duane Currier, Sean Davis, Chand Khanna, Javed Khan, James B. McMahon, Lee J. Helman

    Izdano 2011
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  8. 8
    Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner

    Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner od Matt L. Harlow, Maggie H. Chassé, Elissa A. Boguslawski, Katie M. Sorensen, Jenna M. Gedminas, Susan M. Kitchen-Goosen, Scott B. Rothbart, Cenny Taslim, Stephen L. Lessnick, Anderson Peck, Zachary Madaj, Megan J. Bowman, Patrick J. Grohar

    Izdano 2019
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  9. 9
    Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) New Agents for Ewing Sarcoma Task Force

    Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) New Agents for Ewing Sarcoma Task Force od Kelly M. Bailey, Carrye Cost, Ian J. Davis, Julia Glade Bender, Patrick J. Grohar, Peter J. Houghton, Michael S. Isakoff, Elizabeth Stewart, Nadia N. Laack, Jason T. Yustein, Damon R. Reed, Katherine A. Janeway, Richard Görlick, Stephen L. Lessnick, Steven G. DuBois, Pooja Hingorani

    Izdano 2019
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  10. 10
    Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

    Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma od Patrick J. Grohar, Sun Tae Kim, Guillermo O. Rangel Rivera, Nirmalya Sen, Sara Haddock, Matt L. Harlow, Nichole Maloney, Jack Zhu, Maura O’Neill, Tamara L. Jones, Konrad Hüppi, Magdalena Grandin, Kristen Gehlhaus, Carleen Klumpp‐Thomas, Eugen Buehler, Lee J. Helman, Scott E. Martin, Natasha J. Caplen

    Izdano 2016
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  11. 11
    Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus

    Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus od Matt L. Harlow, Nichole Maloney, Joseph T. Roland, Maria Jose Guillén Navarro, Matthew K. Easton, Susan M. Kitchen-Goosen, Elissa A. Boguslawski, Zachary Madaj, Ben K. Johnson, Megan J. Bowman, Maurizio D’Incalci, Mary E. Winn, Lisa Turner, Galen Hostetter, Carlos M. Galmarini, Pablo Avilés, Patrick J. Grohar

    Izdano 2016
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  12. 12
    Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor

    Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor od Christy Osgood, Nichole Maloney, Christopher G. Kidd, Susan M. Kitchen-Goosen, Laura Segars, Meti Gebregiorgis, Girma M. Woldemichael, Min He, Savita Sankar, Stephen L. Lessnick, Min H. Kang, Malcolm A. Smith, Lisa Turner, Zachary Madaj, Mary E. Winn, Luz-Elena Núñez, Javier González‐Sabín, Lee J. Helman, Francisco Morís, Patrick J. Grohar

    Izdano 2016
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  13. 13
    An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma

    An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma od David S. Shulman, Sarah Burkhead Whittle, Didier Surdez, Kelly M. Bailey, Enrique de Álava, Jason T. Yustein, Adam Shlien, Masanori Hayashi, Alexander J. R. Bishop, Brian D. Crompton, Steven G. DuBois, Neerav Shukla, Patrick J. Leavey, Stephen L. Lessnick, Heinrich Kovar, Olivier Delattre, Thomas G. P. Grünewald, Cristina R. Antonescu, Ryan D. Roberts, Jeffrey A. Toretsky, Franck Tirode, Richard Görlick, Katherine A. Janeway, Damon R. Reed, Elizabeth R. Lawlor, Patrick J. Grohar

    Izdano 2022
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  14. 14
    The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease

    The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease od Heinrich Kovar, James F. Amatruda, Erika Brunet, Stefan Burdach, Florencia Cidre‐Aranaz, Enrique de Álava, Uta Dirksen, Wietske van der Ent, Patrick J. Grohar, Thomas G. P. Grünewald, Lee J. Helman, Peter J. Houghton, Kristiina Iljin, Eberhard Korsching, Marc Ladanyi, Elizabeth R. Lawlor, Stephen L. Lessnick, Joseph A. Ludwig, Paul S. Meltzer, Markus Metzler, Jaume Mora, Richard Moriggl, Takuro Nakamura, Theodore Papamarkou, Branka Radic-Sarikas, Françoise Rédiní, Günther Richter, Claudia Rössig, Keri Schadler, Beat W. Schäfer, Katia Scotlandi, Nathan C. Sheffield, Anang A. Shelat, B. Ewa Snaar‐Jagalska, Poul H. Sorensen, Kimberly Stegmaier, Elizabeth Stewart, E. Alejandro Sweet‐Cordero, Károly Szuhai, Òscar M. Tirado, Franck Tirode, Jeffrey A. Toretsky, Kalliopi Tsafou, Aykut Üren, Andreï Zinovyev, Olivier Delattre

    Izdano 2016
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