Resultats de la cerca - Patrick Engelberts
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Exhaustion of Cytotoxic Effector Systems May Limit Monoclonal Antibody-Based Immunotherapy in Cancer Patients per Frank J. Beurskens, Margaret A. Lindorfer, Mohammed Farooqui, Paul V. Beum, Patrick Engelberts, Wendy J.M. Mackus, Paul W.H.I. Parren, Adrian Wiestner, Ronald P. Taylor
Publicat 2012Artigo -
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Loss of CD20 and Bound CD20 Antibody from Opsonized B Cells Occurs More Rapidly Because of Trogocytosis Mediated by Fc Receptor-Expressing Effector Cells Than Direct Internalizatio... per Paul V. Beum, Elizabeth M. Peek, Margaret A. Lindorfer, Frank J. Beurskens, Patrick Engelberts, Paul W.H.I. Parren, Jan G. J. van de Winkel, Ronald P. Taylor
Publicat 2011Artigo -
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Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy per Fabio Da Roit, Patrick Engelberts, Ronald P. Taylor, Esther C.W. Breij, Giuseppe Gritti, Alessandro Rambaldi, Martino Introna, Paul W.H.I. Parren, Frank J. Beurskens, Josée Golay
Publicat 2014Artigo -
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A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface per Rob N. de Jong, Frank J. Beurskens, Sandra Verploegen, Kristin Strumane, Muriel D. van Kampen, Marleen Voorhorst, Wendy Horstman, Patrick Engelberts, Simone C. Oostindie, Guanbo Wang, Albert J. R. Heck, Janine Schuurman, Paul W.H.I. Parren
Publicat 2016Artigo -
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Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation per Ewald TJ van den Bremer, Frank J. Beurskens, Marleen Voorhorst, Patrick Engelberts, Rob N. de Jong, Burt G van der Boom, Erika M. Cook, Margaret A. Lindorfer, Ronald P. Taylor, Patrick HC van Berkel, Paul W.H.I. Parren
Publicat 2015Artigo -
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DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing per Patrick Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce Meesters, Irati Beltrán Hernández, Simone C. Oostindie, Joost Neijssen, Edward N. van den Brink, G. Jean Horbach, Sandra Verploegen, Aran F. Labrijn, Theodora W. Salcedo, Janine Schuurman, Paul W.H.I. Parren, Esther C.W. Breij
Publicat 2020Artigo -
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Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20 per Magdalena Winiarska, Jacek Bil, Ewa Wilczek, Grzegorz M. Wilczyński, Małgorzata Lekka, Patrick Engelberts, Wendy J.M. Mackus, Elżbieta Górska, Łukasz Bojarski, Tomasz Stokłosa, Dominika Nowis, Zuzanna Kurzaj, Marcin Makowski, Eliza Głodkowska‐Mrówka, Tadeusz Issat, Piotr Mrówka, Witold Lasek, Anna Dąbrowska‐Iwanicka, Grzegorz Basak, M Wasik, Krzysztof Warzocha, Maciej Siński, Zbigniew Gaciong, Marek Jakóbisiak, Paul W.H.I. Parren, Jakub Gołąb
Publicat 2008Artigo
Eines de cerca:
Matèries relacionades
Antibody
Immunology
Biology
Cancer research
Biochemistry
Medicine
Chemistry
In vitro
Molecular biology
Monoclonal antibody
Antigen
CD20
Cell biology
Cytotoxicity
Flow cytometry
Antibody-dependent cell-mediated cytotoxicity
B cell
CD3
CD8
Cancer immunotherapy
Chronic lymphocytic leukemia
Classical complement pathway
Complement system
Gene
Genetics
Immune system
Immunotherapy
Internal medicine
Leukemia
Oncology