نتائج البحث - Patrick Downey
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Engineering synucleinopathy‐resistant human dopaminergic neurons by <scp>CRISPR</scp>‐mediated deletion of the <i><scp>SNCA</scp></i> gene حسب Yixi Chen, Karamjit Singh Dolt, Marco Kriek, Terry Baker, Patrick Downey, Nicola J. Drummond, Maurice A. Canham, Ammar Natalwala, Susan J. Rosser, Tilo Kunath
منشور في 2018Artigo -
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A rapid α‐synuclein seed assay of Parkinson’s disease CSF panel shows high diagnostic accuracy حسب Christina D. Orrù, C. Thong, Andrew G. Hughson, Bradley R. Groveman, Ankit Srivastava, Douglas Galasko, Rachel Angers, Patrick Downey, Karen Crawford, Samantha J. Hutten, Un Jung Kang, Byron Caughey
منشور في 2020Artigo -
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Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody حسب Marie Albert, Georges Mairet‐Coello, Clément Danis, Sarah Lieger, Raphaëlle Caillierez, Sébastien Carrier, Emilie Skrobala, Isabelle Landrieu, Anne Michel, Mathieu Schmitt, Martin Citron, Patrick Downey, Jean‐Philippe Courade, Luc Buée, Morvane Colin
منشور في 2019Artigo -
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Single‐Molecule Two‐Color Coincidence Detection of Unlabeled alpha‐Synuclein Aggregates حسب Alexandre Chappard, Craig Leighton, Rebecca S. Saleeb, Kiani Jeacock, Sarah R. Ball, Katie Morris, Owen Kantelberg, Ji‐Eun Lee, Elsa Zacco, Annalisa Pastore, Margaret Sunde, David J. Clarke, Patrick Downey, Tilo Kunath, Mathew H. Horrocks
منشور في 2023Artigo -
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Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau حسب Jean‐Philippe Courade, Rachel Angers, Georges Mairet‐Coello, Nathalie Pacico, Kerry Tyson, Daniel Lightwood, Rebecca Munro, David McMillan, Robert Griffin, Terry Baker, Dale Starkie, Ruodan Nan, Marta Westwood, Marie-Laetitia Mushikiwabo, Sophie Jung, Geofrey Odede, Berni Sweeney, Andrew G. Popplewell, Gillian Burgess, Patrick Downey, Martin Citron
منشور في 2018Artigo -
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The making of a Lewy body: the role of alpha-synuclein post-fibrillization modifications in regulating the formation and the maturation of pathological inclusions. حسب Anne‐Laure Mahul‐Mellier, Melek Firat Altay, Johannes Burtscher, Niran Maharjan, Nadine Ait‐Bouziad, Anass Chiki, Siv Vingill, Richard Wade‐Martins, Janice L. Holton, Catherine Strand, Caroline Haikal, Jiayi Li, Romain Hamelin, Marie Croisier, Graham Knott, Georges Mairet‐Coello, Laura Weerens, Anne Michel, Patrick Downey, Martin Citron, Hilal A. Lashuel
منشور في 2018Pré-impressão
أدوات البحث:
موضوعات ذات صلة
Biology
Disease
Medicine
Pathology
Gene
Neuroscience
Parkinson's disease
Biochemistry
Cell biology
Genetics
Immunology
Alpha-synuclein
Alzheimer's disease
Antibody
Chemistry
Epitope
Internal medicine
Physics
Tau protein
Amyloid (mycology)
Bioinformatics
Biomarker
Biophysics
CRISPR
Clinical trial
Confocal
Confocal microscopy
Dementia
Dementia with Lewy bodies
Diagnostic accuracy