Suchergebnisse - Patrick Deelen

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  1. 1
    Multi-layered genetic approaches to identify approved drug targets

    Multi-layered genetic approaches to identify approved drug targets von Marie C. Sadler, Chiara Auwerx, Patrick Deelen, Zoltán Kutalik

    Veröffentlicht 2023
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  2. 2
    A Proteomics and Transcriptomics Approach to Identify Leukemic Stem Cell (LSC) Markers

    A Proteomics and Transcriptomics Approach to Identify Leukemic Stem Cell (LSC) Markers von Francesco Bonardi, Fabrizia Fusetti, Patrick Deelen, Djoke van Gosliga, Edo Vellenga, Jan Jacob Schuringa

    Veröffentlicht 2012
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  3. 3
    Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs

    Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs von Monique G.P. van der Wijst, Harm Brugge, Dylan H. de Vries, Patrick Deelen, Morris A. Swertz, Lude Franke

    Veröffentlicht 2018
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  4. 4
    Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration

    Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration von Patrick Deelen, Marc Jan Bonder, K van der Velde, Harm-Jan Westra, Erwin Winder, Dennis Hendriksen, Lude Franke, Morris A. Swertz

    Veröffentlicht 2014
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  5. 5
    Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes

    Lack of Association Between Genetic Variants at ACE2 and TMPRSS2 Genes Involved in SARS-CoV-2 Infection and Human Quantitative Phenotypes von Esteban A. Lopera-Maya, Adriaan van der Graaf, Pauline Lanting, Marije van der Geest, Jingyuan Fu, Morris A. Swertz, Lude Franke, Cisca Wijmenga, Patrick Deelen, Alexandra Zhernakova, Serena Sanna

    Veröffentlicht 2020
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  6. 6
    Population-specific genotype imputations using minimac or IMPUTE2

    Population-specific genotype imputations using minimac or IMPUTE2 von Jin‐Moo Lee, Alexandros Kanterakis, Patrick Deelen, Mathijs Kattenberg, P. Eline Slagboom, Paul I. W. de Bakker, Cisca Wijmenga, Morris A. Swertz, Dorret I. Boomsma, Cornelia M. van Duijn, Lennart C. Karssen, Jouke‐Jan Hottenga

    Veröffentlicht 2015
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  7. 7
    Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

    Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi von Yang Li, Marije Oosting, Patrick Deelen, Isis Ricaño-Ponce, Sanne P. Smeekens, Martin Jaeger, Vasiliki Matzaraki, Morris A. Swertz, Ramnik J. Xavier, Lude Franke, Cisca Wijmenga, Leo A. B. Joosten, Vinod Kumar, Mihai G. Netea

    Veröffentlicht 2016
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  8. 8
    Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels

    Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels von Patrick Deelen, Daria V. Zhernakova, Mark de Haan, Marijke van der Sijde, Marc Jan Bonder, Juha Karjalainen, K. Joeri van der Velde, Kristin M. Abbott, Jingyuan Fu, Cisca Wijmenga, Richard J. Sinke, Morris A. Swertz, Lude Franke

    Veröffentlicht 2015
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  9. 9
    Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

    Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics von Ettje F. Tigchelaar, Alexandra Zhernakova, Jackie Dekens, Gerben D. A. Hermes, Agnieszka Barańska, Zlatan Mujagic, Morris A. Swertz, Angélica María Muñoz Contreras, Patrick Deelen, María Carmen Cénit, Lude Franke, Salome Scholtens, Ronald P. Stolk, Cisca Wijmenga, Edith J. M. Feskens

    Veröffentlicht 2015
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  10. 10
    Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome

    Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome von Daria V. Zhernakova, Trang Le, Alexander Kurilshikov, Biljana Atanasovska, Marc Jan Bonder, Serena Sanna, Annique Claringbould, Urmo Võsa, Patrick Deelen, Lude Franke, Rudolf A. de Boer, Folkert Kuipers, Mihai G. Netea, Marten H. Hofker, Cisca Wijmenga, Alexandra Zhernakova, Jingyuan Fu

    Veröffentlicht 2018
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  11. 11
    TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation

    TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation von Daniel B. Graham, Ariel Lefkovith, Patrick Deelen, Niek de Klein, Mukund Varma, Angela C. Boroughs, A. Nicole Desch, Aylwin Ng, Gaelen Guzman, Monica Schenone, Christine Petersen, Atul K. Bhan, Manuel A. Rivas, Mark J. Daly, Steven A. Carr, Cisca Wijmenga, Ramnik J. Xavier

    Veröffentlicht 2016
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  12. 12
    Functional and Genomic Architecture of Borrelia burgdorferi -Induced Cytokine Responses in Humans

    Functional and Genomic Architecture of Borrelia burgdorferi -Induced Cytokine Responses in Humans von Marije Oosting, Mariska Kerstholt, Rob ter Horst, Yang Li, Patrick Deelen, Sanne P. Smeekens, Martin Jaeger, Ekta Lachmandas, Hedwig D. Vrijmoeth, Mihaela Lupşe, Mirela Flonta, Robert A. Cramer, Bart Jan Kullberg, Vinod Kumar, Ramnik J. Xavier, Cisca Wijmenga, Mihai G. Netea, Leo A. B. Joosten

    Veröffentlicht 2016
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  13. 13
    Gender differences in the mental health impact of the COVID-19 lockdown: Longitudinal evidence from the Netherlands

    Gender differences in the mental health impact of the COVID-19 lockdown: Longitudinal evidence from the Netherlands von A. Vloo, Rob Alessie, Jochen O. Mierau, Marike Boezen, Jochen O. Mierau, Lude Franke, Jackie Dekens, Patrick Deelen, Pauline Lanting, Judith M. Vonk, Ilja M. Nolte, Anil P. S. Ori, Annique Claringbould, Floranne Boulogne, Marjolein X.L. Dijkema, Henry H. Wiersma, Robert Warmerdam, Soesma A. Jankipersadsing

    Veröffentlicht 2021
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  14. 14
    CAPICE: a computational method for Consequence-Agnostic Pathogenicity Interpretation of Clinical Exome variations

    CAPICE: a computational method for Consequence-Agnostic Pathogenicity Interpretation of Clinical Exome variations von Shuang� Li, K. Joeri van der Velde, Dick de Ridder, Aalt D. J. van Dijk, Dimitrios Soudis, Leslie R. Zwerwer, Patrick Deelen, Dennis Hendriksen, Bart Charbon, Mariëlle van Gijn, Kristin M. Abbott, Birgit Sikkema‐Raddatz, Cleo C. van Diemen, Wilhelmina S. Kerstjens‐Frederikse, Richard J. Sinke, Morris A. Swertz

    Veröffentlicht 2020
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  15. 15
    Genetic and epigenetic regulation of gene expression in fetal and adult human livers

    Genetic and epigenetic regulation of gene expression in fetal and adult human livers von Marc Jan Bonder, Silva Kasela, Mart Kals, Riin Tamm, Kaie Lokk, Isabel Barragán, Wim A. Buurman, Patrick Deelen, Jan-Willem M. Greve, Maxim Ivanov, Sander S. Rensen, Jana V. van Vliet‐Ostaptchouk, Marcel G. M. Wolfs, Jingyuan Fu, Marten H. Hofker, Cisca Wijmenga, Alexandra Zhernakova, Magnus Ingelman‐Sundberg, Lude Franke, Lili Milani

    Veröffentlicht 2014
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  16. 16
    Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases

    Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases von Niek de Klein, Ellen Tsai, Martijn Vochteloo, Denis Baird, Yunfeng Huang, Chia‐Yen Chen, Sipko van Dam, Patrick Deelen, Olivier B. Bakker, Omar El Garwany, Zhengyu Ouyang, Eric Marshall, Maria I. Zavodszky, Wouter van Rheenen, Mark K. Bakker, Jan H. Veldink, Tom R. Gaunt, Heiko Runz, Lude Franke, Harm-Jan Westra

    Veröffentlicht 2021
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  17. 17
    Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases

    Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases von Niek de Klein, Ellen Tsai, Martijn Vochteloo, Denis Baird, Yunfeng Huang, Chia‐Yen Chen, Sipko van Dam, Roy Oelen, Patrick Deelen, Olivier B. Bakker, Omar El Garwany, Zhengyu Ouyang, Eric Marshall, Maria I. Zavodszky, Wouter van Rheenen, Mark K. Bakker, Jan H. Veldink, Tom R. Gaunt, Heiko Runz, Lude Franke, Harm-Jan Westra

    Veröffentlicht 2023
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  18. 18
    Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

    Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression von Jingyuan Fu, Marcel G. M. Wolfs, Patrick Deelen, Harm-Jan Westra, Rudolf S.N. Fehrmann, Gerard J. te Meerman, Wim A. Buurman, Sander S. Rensen, Harry J.M. Groen, Rinse K. Weersma, Leonard H. van den Berg, Jan H. Veldink, Roel A. Ophoff, Harold Snieder, David A. van Heel, Ritsert C. Jansen, Marten H. Hofker, Cisca Wijmenga, Lude Franke

    Veröffentlicht 2012
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  19. 19
    RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture

    RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture von Rachel Kleinloog, Bon H. Verweij, Pieter van der Vlies, Patrick Deelen, Morris A. Swertz, Louis De Muynck, Philip Van Damme, Fabrizio Giuliani, Luca Regli, Albert van der Zwan, Jan Willem Berkelbach van der Sprenkel, Kiwan Han, Peter H. Gosselaar, Peter C. van Rijen, Emine Korkmaz, Jan A. Post, Gabriël J.E. Rinkel, Jan H. Veldink, Ynte M. Ruigrok

    Veröffentlicht 2016
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  20. 20
    Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’

    Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’ von Patrick Deelen, Androniki Menelaou, Jin‐Moo Lee, Alexandros Kanterakis, Freerk van Dijk, Carolina Medina‐Gómez, Laurent C. Francioli, Jouke‐Jan Hottenga, Lennart C. Karssen, Karol Estrada, Eskil Kreiner‐Møller, Fernando Rivadeneira, Jessica van Setten, Javier Gutierrez‐Achury, Harm-Jan Westra, Lude Franke, David van Enckevort, Martijn Dijkstra, Heorhiy Byelas, Cornelia M. van Duijn, Paul I. W. de Bakker, Cisca Wijmenga, Morris A. Swertz

    Veröffentlicht 2014
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