Search Results - Patrick A. Zweidler‐McKay

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  1. 1
    Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis

    Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis by Pingyu Zhang, Yanwen Yang, Patrick A. Zweidler‐McKay, Dennis P.M. Hughes

    Published 2008
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  2. 2
    <i>Gfi</i>-1 Encodes a Nuclear Zinc Finger Protein That Binds DNA and Functions as a Transcriptional Repressor

    <i>Gfi</i>-1 Encodes a Nuclear Zinc Finger Protein That Binds DNA and Functions as a Transcriptional Repressor by Patrick A. Zweidler‐McKay, H. Leighton Grimes, Marcella M. Flubacher, Philip N. Tsichlis

    Published 1996
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  3. 3
    Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness

    Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness by Peng Zhang, Yue Yang, Riitta Nolo, Patrick A. Zweidler‐McKay, Dennis P.M. Hughes

    Published 2010
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  4. 4
    The Gfi-1 Proto-Oncoprotein Contains a Novel Transcriptional Repressor Domain, SNAG, and Inhibits G<sub>1</sub> Arrest Induced by Interleukin-2 Withdrawal

    The Gfi-1 Proto-Oncoprotein Contains a Novel Transcriptional Repressor Domain, SNAG, and Inhibits G<sub>1</sub> Arrest Induced by Interleukin-2 Withdrawal by H. Leighton Grimes, Tung O. Chan, Patrick A. Zweidler‐McKay, Betty Tong, Philip N. Tsichlis

    Published 1996
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  5. 5
    Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression

    Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression by Sankaranarayanan Kannan, Wendy Fang, Guangchun Song, Charles G. Mullighan, Richard A. Hammitt, John J.V. McMurray, Patrick A. Zweidler‐McKay

    Published 2011
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  6. 6
    Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia

    Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia by Shao-Qing Kuang, Zhihong Fang, Patrick A. Zweidler‐McKay, Hui Yang, Yue Wei, Emilio A. Gonzalez-Cervantes, Yanis Boumber, Guillermo Garcia‐Manero

    Published 2013
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  7. 7
    Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies

    Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies by Patrick A. Zweidler‐McKay, Yiping He, Lanwei Xu, Carlos G. Rodríguez, Fredrick G. Karnell, Andrea C. Carpenter, Jon C. Aster, David Allman, Warren S. Pear

    Published 2005
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  8. 8
    Ex vivo fucosylation of third-party human regulatory T cells enhances anti–graft-versus-host disease potency in vivo

    Ex vivo fucosylation of third-party human regulatory T cells enhances anti–graft-versus-host disease potency in vivo by Simrit Parmar, Xiaoying Liu, Amer Najjar, Nina Shah, Hong Yang, Eric Yvon, Katy Rezvani, Ian McNiece, Patrick A. Zweidler‐McKay, Leonard P. Miller, Steve Wolpe, Bruce R. Blazar, Elizabeth J. Shpall

    Published 2014
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  9. 9
    CRLF2-Positive B-Cell Acute Lymphoblastic Leukemia in Adult Patients

    CRLF2-Positive B-Cell Acute Lymphoblastic Leukemia in Adult Patients by Sergej Konoplev, Xinyan Lu, Marina Konopleva, Nitin Jain, Juan Ouyang, Maitrayee Goswami, Kathryn G. Roberts, Marc Valentine, Charles G. Mullighan, Carlos Bueso-Ramos, Patrick A. Zweidler‐McKay, Jeffrey L. Jorgensen, Sa A. Wang

    Published 2017
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  10. 10
    Notch activation inhibits AML growth and survival: a potential therapeutic approach

    Notch activation inhibits AML growth and survival: a potential therapeutic approach by Sankaranarayanan Kannan, Robert M. Sutphin, Mandy G. Hall, Leonard S. Golfman, Wendy Fang, Riitta Nolo, Lauren J. Akers, Richard A. Hammitt, John S. McMurray, Steven M. Kornblau, Ari Melnick, María E. Figueroa, Patrick A. Zweidler‐McKay

    Published 2013
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  11. 11
    Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells

    Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells by Maria Inês Almeida, Milena S. Nicoloso, Lizhi Zeng, Cristina Ivan, Riccardo Spizzo, Roberta Gafà, Lianchun Xiao, Xinna Zhang, Ivan Vannini, Francesca Fanini, Muller Fabbri, Giovanni Lanza, Rui Manuel Reis, Patrick A. Zweidler‐McKay, George A. Călin

    Published 2012
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  12. 12
    Targeting Notch signaling in autoimmune and lymphoproliferative disease

    Targeting Notch signaling in autoimmune and lymphoproliferative disease by David T. Teachey, Alix E. Seif, Valerie I. Brown, Marlo Bruno, Ralph M. Bunte, Yueh J. Chang, John Choi, Jonathan D. Fish, Junior Hall, Gregor S. D. Reid, Theresa Ryan, Cecilia Sheen, Patrick A. Zweidler‐McKay, Stephan A. Grupp

    Published 2007
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  13. 13
    Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

    Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1 by Jia Lu, Xiangcang Ye, Fan Fan, Ling Xia, Rajat Bhattacharya, Seth Bellister, Federico Tozzi, Eric Sceusi, Yunfei Zhou, Isamu Tachibana, Dipen M. Maru, David H. Hawke, Janusz Rak, Sendurai A. Mani, Patrick A. Zweidler‐McKay, Lee M. Ellis

    Published 2013
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  14. 14
    CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia

    CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia by Evgeniya Angelova, Charlene A. Audette, Yelena Kovtun, Naval Daver, Sa A. Wang, Sherry Pierce, Sergej Konoplev, Haitham Khogeer, Jeffrey L. Jorgensen, Marina Konopleva, Patrick A. Zweidler‐McKay, L. Jeffrey Medeiros, Hagop M. Kantarjian, Elias Jabbour, Joseph D. Khoury

    Published 2018
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  15. 15
    Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case

    Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case by Birgit Knoechel, Ami S. Bhatt, Pan Li, Chandra Sekhar Pedamallu, Eric A. Severson, Alejandro Gutiérrez, David M. Dorfman, Frank C. Kuo, Michael Kluk, Andrew L. Kung, Patrick A. Zweidler‐McKay, Matthew Meyerson, Stephen C. Blacklow, Daniel J. DeAngelo, Jon C. Aster

    Published 2015
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  16. 16
    Cord Blood Natural Killer Cells Exhibit Impaired Lytic Immunological Synapse Formation That Is Reversed With IL-2 Exvivo Expansion

    Cord Blood Natural Killer Cells Exhibit Impaired Lytic Immunological Synapse Formation That Is Reversed With IL-2 Exvivo Expansion by Dongxia Xing, Alan G. Ramsay, John G. Gribben, William K. Decker, Jared K. Burks, Mark Munsell, Sufang Li, Simon N. Robinson, Hong Yang, David Steiner, Nina Shah, John D. McMannis, Richard E. Champlin, Chitra Hosing, Patrick A. Zweidler‐McKay, Elizabeth J. Shpall, Catherine M. Bollard

    Published 2010
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  17. 17
    Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

    Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) or Blastic Plasmacytoid... by Naval Daver, Pau Montesinos, Daniel J. DeAngelo, Eunice S. Wang, Nikolaos Papadantonakis, Éric Deconinck, Harry P. Erba, Naveen Pemmaraju, Andrew A. Lane, David A. Rizzieri, Kendra Sweet, Giovanni Martinelli, Corrado Tarella, Elisabetta Todisco, Marina Konopleva, Callum M. Sloss, Kerry Culm-Merdek, Patrick A. Zweidler‐McKay, Hagop M. Kantarjian

    Published 2019
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  18. 18
    Pronounced Hypoxia in Models of Murine and Human Leukemia: High Efficacy of Hypoxia-Activated Prodrug PR-104

    Pronounced Hypoxia in Models of Murine and Human Leukemia: High Efficacy of Hypoxia-Activated Prodrug PR-104 by Juliana Benito, Yuexi Shi, Barbara Szymanska, Hernán Carol, Ingrid Boehm, Hongbo Lu, Sergej Konoplev, Wendy Fang, Patrick A. Zweidler‐McKay, Dario Campana, Gautam Borthakur, Carlos E. Bueso‐Ramos, Elizabeth J. Shpall, Deborah A. Thomas, Craig T. Jordan, Hagop M. Kantarjian, William R. Wilson, Richard B. Lock, Michael Andreeff, Marina Konopleva

    Published 2011
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  19. 19
    Central nervous system status is prognostic in T-cell acute lymphoblastic leukemia: a Children’s Oncology Group report

    Central nervous system status is prognostic in T-cell acute lymphoblastic leukemia: a Children’s Oncology Group report by Nathan Gossai, Meenakshi Devidas, Zhiguo Chen, Brent L. Wood, Patrick A. Zweidler‐McKay, Karen R. Rabin, Mignon L. Loh, Elizabeth A. Raetz, Naomi J. Winick, Michael J. Burke, Andrew J. Carroll, Natia Esiashvili, Nyla A. Heerema, William L. Carroll, Stephen P. Hunger, Kimberly P. Dunsmore, Stuart S. Winter, David T. Teachey

    Published 2023
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  20. 20
    Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2Rγnull mice

    Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2Rγnull mice by Simon N. Robinson, Paul J. Simmons, Michael W. Thomas, Nathalie Brouard, Jeannie A. Javni, Suprita Trilok, Jae-Seung Shim, Hong Yang, David Steiner, William K. Decker, Dongxia Xing, Leonard D. Shultz, Barbara Savoldo, Gianpietro Dotti, Catherine M. Bollard, Leonard P. Miller, Richard E. Champlin, Elizabeth J. Shpall, Patrick A. Zweidler‐McKay

    Published 2012
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