Ngā hua rapu - Pascale Fouqueray
- E whakaatu ana i te 1 - 13 hua o te 13
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Efficacy and safety of imeglimin in Japanese patients with type 2 diabetes: A 24‐week, randomized, double‐blind, placebo‐controlled, dose‐ranging phase 2b trial mā Julie Dubourg, Kohjiro Ueki, Jean‐Marie Grouin, Pascale Fouqueray
I whakaputaina 2020Artigo -
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Efficacy and Safety of Imeglimin Monotherapy Versus Placebo in Japanese Patients With Type 2 Diabetes (TIMES 1): A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Mul... mā Julie Dubourg, Pascale Fouqueray, Carole Thang, Jean‐Marie Grouin, Kohjiro Ueki
I whakaputaina 2021Artigo -
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Long‐term safety and efficacy of imeglimin as monotherapy or in combination with existing antidiabetic agents in Japanese patients with type 2 diabetes (<scp>TIMES</scp> 2): A 52‐w... mā Julie Dubourg, Pascale Fouqueray, Damien Quinslot, Jean‐Marie Grouin, Kohei Kaku
I whakaputaina 2021Artigo -
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Efficacy and safety of imeglimin add‐on to insulin monotherapy in Japanese patients with type 2 diabetes (<scp>TIMES</scp> 3): A randomized, double‐blind, placebo‐controlled phase... mā Caroline Reilhac, Julie Dubourg, Carole Thang, Jean‐Marie Grouin, Pascale Fouqueray, Hirotaka Watada
I whakaputaina 2022Artigo -
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The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy mā Pascale Fouqueray, Valdis Pīrāgs, Silvio E. Inzucchi, Clifford J. Bailey, Guntram Schernthaner, Michaëla Diamant, Harold E. Lebovitz
I whakaputaina 2012Artigo -
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The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Sitagliptin Monotherapy mā Pascale Fouqueray, Valdis Pīrāgs, Michaëla Diamant, Guntram Schernthaner, Harold E. Lebovitz, Silvio E. Inzucchi, Clifford J. Bailey
I whakaputaina 2014Artigo -
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Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration mā Dominique Détaille, Guillaume Vial, Anne‐Laure Borel, Cécile Cottet-Rouselle, Sophie Hallakou‐Bozec, Sébastien Bolze, Pascale Fouqueray, Éric Fontaine
I whakaputaina 2016Artigo -
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Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents mā Rachel J. Perry, Rebecca Cardone, Max C. Petersen, Dongyan Zhang, Pascale Fouqueray, Sophie Hallakou‐Bozec, Sébastien Bolze, Gerald I. Shulman, Kitt Falk Petersen, Richard G. Kibbey
I whakaputaina 2016Artigo -
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Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity mā Vincent Jacques, Sébastien Bolze, Sophie Hallakou‐Bozec, Anthony W. Czarnik, Ajit S. Divakaruni, Pascale Fouqueray, Anne N. Murphy, Lex H.T. Van der Ploeg, Sheila H. DeWitt
I whakaputaina 2021Artigo
Ngā utauta rapu:
Ngā marau whai pānga
Endocrinology
Diabetes mellitus
Internal medicine
Medicine
Type 2 diabetes
Insulin
Alternative medicine
Pathology
Pharmacology
Placebo
Adverse effect
Biology
Clinical endpoint
Randomized controlled trial
Biochemistry
Chemistry
Enzyme
In vitro
Metformin
Apoptosis
Cell biology
Clinical trial
Gastroenterology
Glucose uptake
Glycemic
Mechanism of action
Mitochondrial permeability transition pore
NAD+ kinase
Programmed cell death
Secretion