Torthaí cuardaigh - Pascale Fouqueray
- 1 - 13 toradh as 13 á dtaispeáint
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Efficacy and safety of imeglimin in Japanese patients with type 2 diabetes: A 24‐week, randomized, double‐blind, placebo‐controlled, dose‐ranging phase 2b trial de réir Julie Dubourg, Kohjiro Ueki, Jean‐Marie Grouin, Pascale Fouqueray
Foilsithe / Cruthaithe 2020Artigo -
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Imeglimin - A New Oral Anti-Diabetic that Targets the Three Key Defects of type 2 Diabetes de réir Pascale Fouqueray, Xavier Leverve, Éric Fontaine, Mathurin Baquié, Claes B. Wollheim
Foilsithe / Cruthaithe 2011Artigo -
4
Efficacy and Safety of Imeglimin Monotherapy Versus Placebo in Japanese Patients With Type 2 Diabetes (TIMES 1): A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Mul... de réir Julie Dubourg, Pascale Fouqueray, Carole Thang, Jean‐Marie Grouin, Kohjiro Ueki
Foilsithe / Cruthaithe 2021Artigo -
5
Long‐term safety and efficacy of imeglimin as monotherapy or in combination with existing antidiabetic agents in Japanese patients with type 2 diabetes (<scp>TIMES</scp> 2): A 52‐w... de réir Julie Dubourg, Pascale Fouqueray, Damien Quinslot, Jean‐Marie Grouin, Kohei Kaku
Foilsithe / Cruthaithe 2021Artigo -
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Efficacy and safety of imeglimin add‐on to insulin monotherapy in Japanese patients with type 2 diabetes (<scp>TIMES</scp> 3): A randomized, double‐blind, placebo‐controlled phase... de réir Caroline Reilhac, Julie Dubourg, Carole Thang, Jean‐Marie Grouin, Pascale Fouqueray, Hirotaka Watada
Foilsithe / Cruthaithe 2022Artigo -
8
The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy de réir Pascale Fouqueray, Valdis Pīrāgs, Silvio E. Inzucchi, Clifford J. Bailey, Guntram Schernthaner, Michaëla Diamant, Harold E. Lebovitz
Foilsithe / Cruthaithe 2012Artigo -
9
The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Sitagliptin Monotherapy de réir Pascale Fouqueray, Valdis Pīrāgs, Michaëla Diamant, Guntram Schernthaner, Harold E. Lebovitz, Silvio E. Inzucchi, Clifford J. Bailey
Foilsithe / Cruthaithe 2014Artigo -
10
Imeglimin prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration de réir Dominique Détaille, Guillaume Vial, Anne‐Laure Borel, Cécile Cottet-Rouselle, Sophie Hallakou‐Bozec, Sébastien Bolze, Pascale Fouqueray, Éric Fontaine
Foilsithe / Cruthaithe 2016Artigo -
11
Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes de réir Sophie Hallakou‐Bozec, Guillaume Vial, Micheline Kergoat, Pascale Fouqueray, Sébastien Bolze, Anne‐Laure Borel, Éric Fontaine, David E. Moller
Foilsithe / Cruthaithe 2020Revisão -
12
Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents de réir Rachel J. Perry, Rebecca Cardone, Max C. Petersen, Dongyan Zhang, Pascale Fouqueray, Sophie Hallakou‐Bozec, Sébastien Bolze, Gerald I. Shulman, Kitt Falk Petersen, Richard G. Kibbey
Foilsithe / Cruthaithe 2016Artigo -
13
Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity de réir Vincent Jacques, Sébastien Bolze, Sophie Hallakou‐Bozec, Anthony W. Czarnik, Ajit S. Divakaruni, Pascale Fouqueray, Anne N. Murphy, Lex H.T. Van der Ploeg, Sheila H. DeWitt
Foilsithe / Cruthaithe 2021Artigo
Uirlisí cuardaigh:
Ábhair a bhaineann le hábhar
Endocrinology
Diabetes mellitus
Internal medicine
Medicine
Type 2 diabetes
Insulin
Alternative medicine
Pathology
Pharmacology
Placebo
Adverse effect
Biology
Clinical endpoint
Randomized controlled trial
Biochemistry
Chemistry
Enzyme
In vitro
Metformin
Apoptosis
Cell biology
Clinical trial
Gastroenterology
Glucose uptake
Glycemic
Mechanism of action
Mitochondrial permeability transition pore
NAD+ kinase
Programmed cell death
Secretion