Resultados da pesquisa - Pascal D. Johann

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  1. 1
    RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

    RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression Por Pascal D. Johann, Natalie Jäger, Stefan M. Pfister, Martin Sill

    Publicado em 2019
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  2. 2
    SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

    SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability Por Alison D. Parisian, Tomoyuki Koga, Shunichiro Miki, Pascal D. Johann, Marcel Kool, John R. Crawford, Frank B. Furnari

    Publicado em 2020
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  3. 3
    Current and Emerging Therapeutic Approaches for Extracranial Malignant Rhabdoid Tumors

    Current and Emerging Therapeutic Approaches for Extracranial Malignant Rhabdoid Tumors Por Karolina Nemes, Pascal D. Johann, Stefanie Tüchert, Patrick Melchior, Christian Vokuhl, Reiner Siebert, Rhoikos Furtwängler, Michael C. Frühwald

    Publicado em 2022
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  4. 4
    DICER1 Mutational Spectrum in Intracranial CNS-Neoplasias—A Review and a Report from the CNS-InterREST GPOH Study Center

    DICER1 Mutational Spectrum in Intracranial CNS-Neoplasias—A Review and a Report from the CNS-InterREST GPOH Study Center Por Selma Manea, Victoria E. Fincke, Michael C. Frühwald, Dominik Sturm, Barbara von Zezschwitz, Pascal D. Johann, Marlena Mucha

    Publicado em 2025
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  5. 5
    Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor

    Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor Por Johannes Nowak, Karolina Nemes, Annika Hohm, Lindsey A. Vandergrift, Martin Hasselblatt, Pascal D. Johann, Marcel Kool, Michael C. Frühwald, Monika Warmuth‐Metz

    Publicado em 2018
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  6. 6
    Molecular subgrouping of atypical teratoid/rhabdoid tumors—a reinvestigation and current consensus

    Molecular subgrouping of atypical teratoid/rhabdoid tumors—a reinvestigation and current consensus Por Ben Ho, Pascal D. Johann, Yura Grabovska, Mamy Andrianteranagna, Fupan Yao, Michael C. Frühwald, Martin Hasselblatt, Franck Bourdeaut, Daniel Williamson, Annie Huang, Marcel Kool

    Publicado em 2019
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  7. 7
    Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor

    Molecular analyses reveal close similarities between small cell carcinoma of the ovary, hypercalcemic type and atypical teratoid/rhabdoid tumor Por Somayyeh Fahiminiya, Leora Witkowski, Javad Nadaf, Jian Carrot‐Zhang, Catherine Goudie, Martin Hasselblatt, Pascal D. Johann, Marcel Kool, Ryan S. Lee, Tenzin Gayden, Charles W.M. Roberts, Jaclyn A. Biegel, Nada Jabado, Jacek Majewski, William D. Foulkes

    Publicado em 2015
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  8. 8
    Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases

    Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases Por Dörthe Holdhof, Pascal D. Johann, Michael Spohn, Michael Bockmayr, Sepehr Safaei, Piyush Joshi, Julien Masliah‐Planchon, Ben Ho, Mamy Andrianteranagna, Franck Bourdeaut, Annie Huang, Marcel Kool, Santhosh A. Upadhyaya, Anne Bendel, Daniela Indenbirken, William D. Foulkes, Jonathan W. Bush, David Creytens, Uwe Kordes, Michael C. Frühwald, Martin Hasselblatt, Ulrich Schüller

    Publicado em 2020
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  9. 9
    Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

    Papillary Tumor of the Pineal Region: A Distinct Molecular Entity Por Stephanie Heim, Martin Sill, David Jones, Alexandre Vasiljevic, Anne Jouvet, Michelle Fèvre‐Montange, Pieter Wesseling, Rudi Beschorner, Michel Mittelbronn, Patricia Kohlhof, Volker Hovestadt, Pascal D. Johann, Marcel Kool, Kristian W. Pajtler, Andrey Korshunov, Vincent Ruland, Jan Sperveslage, Christian Thomas, Hendrik Witt, Andreas von Deimling, Werner Paulus, Stefan M. Pfister, David Capper, Martin Hasselblatt

    Publicado em 2015
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  10. 10
    ATRT-15. Primordial germ cells identified as one potential cell of origin of MYC rhabdoid tumors

    ATRT-15. Primordial germ cells identified as one potential cell of origin of MYC rhabdoid tumors Por Monika Graf, Marta Interlandi, Natalia Moreno, Rajanya Roy, Dörthe Holdhof, Carolin Göbel, Viktoria Melcher, Julius Mertins, Thomas Albert, Dennis Kastrati, Amelie Alfert, Till Holsten, Flavia de Faria, Michael Meisterernst, Claudia Rössig, Monika Warmuth‐Metz, Johannes Nowak, Gerd Meyer zu Hörste, Chloé Mayère, Serge Nef, Pascal D. Johann, Michael C. Frühwald, Martin Dugas, Ulrich Schüller, Kornelius Kerl

    Publicado em 2022
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  11. 11
    Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1‐deficient non‐rhabdoid tumor with favorable long‐term outcome

    Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1‐deficient non‐rhabdoid tumor with favorable long‐term outcome Por Pascal D. Johann, Volker Hovestadt, Christian Thomas, Astrid Jeibmann, Katharina Heß, Susanne Bens, Florian Oyen, Cynthia Hawkins, Christopher R. Pierson, Kenneth Aldape, Sang‐Pyo Kim, Eva Widing, David Sumerauer, Péter Hauser, Frank K.H. van Landeghem, Marina Ryzhova, Andrey Korshunov, David Capper, David Jones, Stefan M. Pfister, Reinhard Schneppenheim, Reiner Siebert, Werner Paulus, Michael C. Frühwald, Marcel Kool, Martin Hasselblatt

    Publicado em 2016
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  12. 12
    Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation

    Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation Por Serap Erkek, Pascal D. Johann, Martina Finetti, Yiannis Drosos, Hsien-Chao Chou, Marc Zapatka, Dominik Sturm, David Jones, Andrey Korshunov, Marina Rhyzova, Stephan Wolf, Jan‐Philipp Mallm, Katja Beck, Olaf Witt, Andreas E. Kulozik, Michael C. Frühwald, Paul A. Northcott, Jan O. Korbel, Peter Lichter, Roland Eils, Amar Gajjar, Charles W.M. Roberts, Daniel Williamson, Martin Hasselblatt, Lukas Chávez, Stefan M. Pfister, Marcel Kool

    Publicado em 2018
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  13. 13
    Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

    Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors Por Johanna Theruvath, Elena Sotillo, Christopher Mount, Claus Moritz Graef, Alberto Delaidelli, Sabine Heitzeneder, Louai Labanieh, Shaurya Dhingra, Amaury Leruste, Robbie G. Majzner, Peng Xu, Sabine Mueller, Derek Yecies, Martina Finetti, Daniel Williamson, Pascal D. Johann, Marcel Kool, Stefan M. Pfister, Martin Hasselblatt, Michael C. Frühwald, Olivier Delattre, Didier Surdez, Franck Bourdeaut, Stéphanie Puget, Sakina Zaïdi, Siddhartha S. Mitra, Samuel Cheshier, Poul H. Sorensen, Michelle Monje, Crystal L. Mackall

    Publicado em 2020
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  14. 14
    ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

    ATRT–SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance Por Aniello Federico, Christian Thomas, Katarzyna Miśkiewicz, Niklas Woltering, Francesca Zin, Karolina Nemes, Brigitte Bison, Pascal D. Johann, Debra Hawes, Susanne Bens, Uwe Kordes, Steffen Albrecht, Hildegard Dohmen, Péter Hauser, Kathy Keyvani, Frank K.H. van Landeghem, Eva Løbner Lund, David Scheie, Christian Mawrin, Camelia‐Maria Monoranu, Benedicte Parm Ulhøi, Torsten Pietsch, Harald Reinhard, Markus J. Riemenschneider, Astrid Sehested, David Sumerauer, Reiner Siebert, Werner Paulus, Michael C. Frühwald, Marcel Kool, Martin Hasselblatt

    Publicado em 2022
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  15. 15
    Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

    Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration Por Hye-Jung E. Chun, Pascal D. Johann, Katy Milne, Marc Zapatka, Annette Buellesbach, Naveed Ishaque, Murat Iskar, Serap Erkek, Lisa L. Wei, Basile Tessier‐Cloutier, Jake Lever, Emma Titmuss, James T. Topham, Reanne Bowlby, Eric Chuah, Karen Mungall, Yussanne Ma, Andrew J. Mungall, Richard A. Moore, Michael D. Taylor, Daniela S. Gerhard, Steven J.M. Jones, Andrey Korshunov, Manfred Gessler, Kornelius Kerl, Martin Hasselblatt, Michael C. Frühwald, Elizabeth J. Perlman, Brad H. Nelson, Stefan M. Pfister, Marco A. Marra, Marcel Kool

    Publicado em 2019
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  16. 16
    Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials

    Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials Por Santhosh A. Upadhyaya, Giles Robinson, Arzu Onar‐Thomas, Brent A. Orr, Pascal D. Johann, Gang Wu, Catherine A. Billups, Ruth Tatevossian, Sandeep Kumar Dhanda, Ashok Srinivasan, Alberto Broniscer, Ibrahim Qaddoumi, Anna Vinitsky, Gregory T. Armstrong, Anne Bendel, Tim Hassall, Sonia Partap, Paul G. Fisher, John R. Crawford, Murali Chintagumpala, Éric Bouffet, Sridharan Gururangan, Roya Mostafavi, Robert P. Sanders, Paul Klimo, Zoltán Patay, Daniel J. Indelicato, Kim E. Nichols, Frederick A. Boop, Thomas E. Merchant, Marcel Kool, David W. Ellison, Amar Gajjar

    Publicado em 2021
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  17. 17
    Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas

    Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas Por Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, David Jones, Marcel Kool, Marc Zapatka, Paul A. Northcott, Dominik Sturm, Wei Wang, Bernhard Radlwimmer, Jonas W. Højfeldt, Nathalène Truffaux, David Castel, Simone Schubert, Marina Ryzhova, Huriye Seker‐Cin, Jan Gronych, Pascal D. Johann, Sebastian Stark, Jochen Meyer, Till Milde, Martin U. Schuhmann, Martin Ebinger, Camelia-Maria Monoranu, Anitha Ponnuswami, Spenser Chen, Chris Jones, Olaf Witt, V. Peter Collins, Andreas von Deimling, Nada Jabado, Stéphanie Puget, Jacques Grill, Kristian Helin, Andrey Korshunov, Peter Lichter, Michelle Monje, Christoph Plass, Yoon-Jae Cho, Stefan M. Pfister

    Publicado em 2013
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  18. 18
    Active medulloblastoma enhancers reveal subgroup-specific cellular origins

    Active medulloblastoma enhancers reveal subgroup-specific cellular origins Por Charles Y. Lin, Serap Erkek, Yiai Tong, Linlin Yin, Alexander Federation, Marc Zapatka, Parthiv Haldipur, Daisuke Kawauchi, Thomas S. Risch, Hans-Jörg Warnatz, Barbara C. Worst, Bensheng Ju, Brent A. Orr, Rhamy Zeid, Donald R. Polaski, Maia Segura‐Wang, Sebastian M. Waszak, David Jones, Marcel Kool, Volker Hovestadt, Ivo Buchhalter, Laura Sieber, Pascal D. Johann, Lukas Chávez, Stefan Gröschel, Marina Ryzhova, Andrey Korshunov, Wenbiao Chen, Victor V. Chizhikov, Kathleen J. Millen, Vyacheslav Amstislavskiy, Hans Lehrach, Marie-Laure Yaspo, Roland Eils, Peter Lichter, Jan O. Korbel, Stefan M. Pfister, James E. Bradner, Paul A. Northcott

    Publicado em 2016
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  19. 19
    Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors

    Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors Por Michael C. Frühwald, Martin Hasselblatt, Karolina Nemes, Susanne Bens, Mona Steinbügl, Pascal D. Johann, Kornelius Kerl, Péter Hauser, Eduardo Quiroga, Palma Solano‐Páez, Veronica Biassoni, Maria João Gil‐da‐Costa, Martha Perek-Polnik, Marianne D. van de Wetering, David Sumerauer, Jane Pears, Niklas Stabell, Stefan Holm, Heinz Hengartner, Nicolas U. Gerber, Michael Grotzer, Joachim Boos, Martin Ebinger, Stefan Tippelt, Werner Paulus, Rhoikos Furtwängler, Pablo Hernáiz Driever, Harald Reinhard, Stefan Rutkowski, Paul‐Gerhardt Schlegel, Irene Schmid, Rolf‐Dieter Kortmann, Beate Timmermann, Monika Warmuth‐Metz, Uwe Kordes, Joachim Gerß, Karsten Nysom, Reinhard Schneppenheim, Reiner Siebert, Marcel Kool, Norbert Graf

    Publicado em 2019
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  20. 20
    NFB-13. Rhabdoid Tumor Predisposition Syndrome (RTPS) – Finding Evidence by systematic Analyses

    NFB-13. Rhabdoid Tumor Predisposition Syndrome (RTPS) – Finding Evidence by systematic Analyses Por Karolina Nemes, Susanne Bens, Pascal D. Johann, Mona Steinbügl, Miriam Gruhle, Denis Kachanov, M. V. Teleshova, Péter Hauser, Thorsten Simon, Stephan Tippelt, W. Eberl, Wilhelm Woessmann, Christian P. Kratz, Floor Abbink, Pablo Hernáiz Driever, Matthias Eyrich, David Sumerauer, Till Milde, Harald Reinhard, Alfred Leipold, Marianne D. van de Wetering, Maria João Gil‐da‐Costa, Georg Ebetsberger‐Dachs, Carmen Hernández Marqúes, Nina Bauer, Veronica Biassoni, Clarice Franco Meneses, Stephanie Knirsch, Melchior Lauten, Nicolas U. Gerber, Martin Chada, Kornelius Kerl, Andreas Lemmer, Heidrun Boztug, Michaela Kuhlen, Rhoikos Furtwängler, Uwe Kordes, Reiner Schneppenheim, Christian Vokuhl, Martin Hasselblatt, Thomas Kröncke, Brigitte Bison, Patrick Melchior, Beate Timmermann, Joachim Gerß, Reiner Siebert, Michael C. Frühwald

    Publicado em 2022
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