Hakutulokset - Parasvi S. Patel

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  1. 1
    APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability

    APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability Tekijä Ajinkya S. Kawale, Xiaojuan Ran, Parasvi S. Patel, Sneha Saxena, Michael S. Lawrence, Lee Zou

    Julkaistu 2024
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  2. 2
    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms Tekijä Wendy Leung, Antoine Simoneau, Sneha Saxena, Jessica Jackson, Parasvi S. Patel, Mangsi Limbu, Alessandro Vindigni, Lee Zou

    Julkaistu 2023
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  3. 3
    The RNA m5C modification in R-loops as an off switch of Alt-NHEJ

    The RNA m5C modification in R-loops as an off switch of Alt-NHEJ Tekijä Haibo Yang, Emily M. Lachtara, Xiaojuan Ran, Jessica Hopkins, Parasvi S. Patel, Xueping Zhu, Yao Xiao, Laiyee Phoon, Boya Gao, Lee Zou, Michael S. Lawrence, Li Lan

    Julkaistu 2023
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  4. 4
    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

    Unprocessed genomic uracil as a source of DNA replication stress in cancer cells Tekijä Sneha Saxena, Christopher S. Nabel, Turner W. Seay, Parasvi S. Patel, Ajinkya S. Kawale, Caroline R. Crosby, Helene Tigro, Eugene Oh, Matthew G. Vander Heiden, Aaron N. Hata, Zucai Suo, Lee Zou

    Julkaistu 2024
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  5. 5
    ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy

    ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy Tekijä Mingchao Wang, Xiaojuan Ran, Wendy Leung, Ajinkya S. Kawale, Sneha Saxena, Jian Ouyang, Parasvi S. Patel, Yuting Dong, Tao Yin, Jian Shu, Robert T. Manguso, Li Lan, Xiao‐Fan Wang, Michael S. Lawrence, Lee Zou

    Julkaistu 2023
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  6. 6
    RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation

    RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation Tekijä Kiran Kumar Naidu Guturi, Miyuki Bohgaki, Toshiyuki Bohgaki, Tharan Srikumar, Deborah Ng, Ramya Kumareswaran, Samah El Ghamrasni, Justin Y Jeon, Parasvi S. Patel, Mohamed Saad Eldin, Robert G. Bristow, Peter Cheung, Grant S. Stewart, Brian Raught, Anne Hakem, Razqallah Hakem

    Julkaistu 2016
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  7. 7
    Excessive transcription-replication conflicts are a vulnerability of <i>BRCA1</i>-mutant cancers

    Excessive transcription-replication conflicts are a vulnerability of <i>BRCA1</i>-mutant cancers Tekijä Parasvi S. Patel, Arash Algouneh, Rehna Krishnan, John J. Reynolds, Kevin C. Nixon, Jun Hao, Jihoon Lee, Yue Feng, Chehronai Fozil, Mia Stanić, Talya Yerlici, Peiran Su, Fraser Soares, Elisabeth Liedtke, Gil Privé, Gary D Baider, Miguel Ángel Pujana, Karim Mekhail, Housheng Hansen He, Anne Hakem, Grant S. Stewart, Razqallah Hakem

    Julkaistu 2023
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  8. 8
    Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19

    Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19 Tekijä Junjie T. Hua, Musaddeque Ahmed, Haiyang Guo, Yuzhe Zhang, Sujun Chen, Fraser Soares, Jennifer Lu, Stanley Zhou, Miranda Wang, Hui Li, Nicholas B. Larson, Shannon K. McDonnell, Parasvi S. Patel, Yi Liang, Cindy Q. Yao, Theodorus van der Kwast, Mathieu Lupien, Felix Y. Feng, Amina Zoubeidi, Ming‐Sound Tsao, Stephen N. Thibodeau, Paul C. Boutros, Housheng Hansen He

    Julkaistu 2018
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  9. 9
    Nucleolar RNA polymerase II drives ribosome biogenesis

    Nucleolar RNA polymerase II drives ribosome biogenesis Tekijä Karan Joshua Abraham, Negin Khosraviani, Janet N.Y. Chan, Aparna Gorthi, Anas Samman, Dorothy Yanling Zhao, Miling Wang, Michael Bokros, Elva Vidya, Lauren Ostrowski, Roxanne Oshidari, Violena Pietrobon, Parasvi S. Patel, Arash Algouneh, Rajat Singhania, Yupeng Liu, V. Talya Yerlici, Daniel D. De Carvalho, Michael Ohh, Brendan C. Dickson, Razqallah Hakem, Jack Greenblatt, Stephen Lee, Alexander J. R. Bishop, Karim Mekhail

    Julkaistu 2020
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  10. 10
    RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors

    RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors Tekijä Parasvi S. Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie‐jo Halaby, Zahra Khan, Luís Palomero, Brandon Ho, Shili Duan, Jonathan St‐Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R. Barnes, Jonathan Beesley, Otto Sánchez, Hal K. Berman, Grant W. Brown, El Bachir Affar, Georgia Chenevix‐Trench, Antonis C. Antoniou, C.H. Arrowsmith, Brian Raught, Miguel Ángel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem

    Julkaistu 2021
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  11. 11
    The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

    The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness Tekijä Geethu Emily Thomas, Grace Egan, Laura García‐Prat, Aaron Botham, Véronique Voisin, Parasvi S. Patel, Fieke W. Hoff, J Chin, Boaz Nachmias, Kerstin B. Kaufmann, Dilshad H. Khan, Rose Hurren, Xiaoming Wang, Marcela Gronda, Neil MacLean, Cristiana O’Brien, Rashim Pal Singh, Courtney L. Jones, Shane M. Harding, Brian Raught, Andrea Arruda, Mark D. Minden, Gary D. Bader, Razqallah Hakem, Steve Kornblau, John E. Dick, Aaron D. Schimmer

    Julkaistu 2022
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  12. 12
    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells Tekijä Rehna Krishnan, Mariah Lapierre, Brandon Gautreau, Kevin C. Nixon, Samah El Ghamrasni, Parasvi S. Patel, Jun Hao, V. Talya Yerlici, Kiran Kumar Naidu Guturi, Jonathan St‐Germain, Francesca Mateo, Amine Saad, Arash Algouneh, Rebecca Earnshaw, Duan Shili, Alma Seitova, Joshua W. Miller, Negin Khosraviani, Adam Penn, Brandon Ho, Otto Sánchez, M. Prakash Hande, Jean‐Yves Masson, Grant W. Brown, Moulay A. Alaoui‐Jamali, John J. Reynolds, C.H. Arrowsmith, Brian Raught, Miguel Ángel Pujana, Karim Mekhail, Grant S. Stewart, Anne Hakem, Razqallah Hakem

    Julkaistu 2023
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