Rezultati - Parameswaran G. Sreekumar

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  1. 1
    Novel roles for α-crystallins in retinal function and disease

    Novel roles for α-crystallins in retinal function and disease od Ram Kannan, Parameswaran G. Sreekumar, David R. Hinton

    Izdano 2012
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  2. 2
    The Emerging Role of Senescence in Ocular Disease

    The Emerging Role of Senescence in Ocular Disease od Parameswaran G. Sreekumar, David R. Hinton, Ram Kannan

    Izdano 2020
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  3. 3
    Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration

    Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration od Parameswaran G. Sreekumar, Deborah A. Ferrington, Ram Kannan

    Izdano 2021
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  4. 4
    Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration

    Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration od Ram Kannan, Parameswaran G. Sreekumar, David R. Hinton

    Izdano 2015
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  5. 5
    Protective Mechanisms of the Mitochondrial‐Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells

    Protective Mechanisms of the Mitochondrial‐Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells od Leonid Minasyan, Parameswaran G. Sreekumar, David R. Hinton, Ram Kannan

    Izdano 2017
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  6. 6
    Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD

    Mechanisms of RPE senescence and potential role of αB crystallin peptide as a senolytic agent in experimental AMD od Parameswaran G. Sreekumar, Srinivasa T. Reddy, David R. Hinton, Ram Kannan

    Izdano 2022
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  7. 7
    Protection of Retina by αB Crystallin in Sodium Iodate Induced Retinal Degeneration

    Protection of Retina by αB Crystallin in Sodium Iodate Induced Retinal Degeneration od Peng Zhou, Ram Kannan, Christine Spee, Parameswaran G. Sreekumar, Guo‐Rui Dou, David R. Hinton

    Izdano 2014
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  8. 8
    Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

    Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia od Jennifer Yaung, Ram Kannan, Eric F. Wawrousek, Christine Spee, Parameswaran G. Sreekumar, David R. Hinton

    Izdano 2007
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  9. 9
    αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition

    αB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition od Keijiro Ishikawa, Parameswaran G. Sreekumar, Christine Spee, Hossein Nazari, Danhong Zhu, Ram Kannan, David R. Hinton

    Izdano 2016
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  10. 10
    Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

    Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux od Parameswaran G. Sreekumar, Christine Spee, Stephen J. Ryan, Susan P.C. Cole, Ram Kannan, David R. Hinton

    Izdano 2012
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  11. 11
    αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells

    αB Crystallin Is Apically Secreted within Exosomes by Polarized Human Retinal Pigment Epithelium and Provides Neuroprotection to Adjacent Cells od Parameswaran G. Sreekumar, Ram Kannan, Mizuki Kitamura, Christine Spee, Ernesto Barrón, Stephen J. Ryan, David R. Hinton

    Izdano 2010
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  12. 12
    Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

    Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration od Shozo Sonoda, Parameswaran G. Sreekumar, Satoru Kase, Christine Spee, Stephen J. Ryan, Ram Kannan, David R. Hinton

    Izdano 2009
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  13. 13
    Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction

    Deficiency of αB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction od Guo‐Rui Dou, Parameswaran G. Sreekumar, Christine Spee, Shikun He, Stephen J. Ryan, Ram Kannan, David R. Hinton

    Izdano 2012
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  14. 14
    Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione

    Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione od Douglas Matsunaga, Parameswaran G. Sreekumar, Keijiro Ishikawa, Hiroto Terasaki, Ernesto Barrón, Pinchas Cohen, Ram Kannan, David R. Hinton

    Izdano 2016
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  15. 15
    Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration

    Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration od Parameswaran G. Sreekumar, Zhe Li, Wan Wang, Christine Spee, David R. Hinton, Ram Kannan, J. Andrew MacKay

    Izdano 2018
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  16. 16
    The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction

    The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction od Parameswaran G. Sreekumar, Keijiro Ishikawa, Chris Spee, Hemal H. Mehta, Junxiang Wan, Kelvin Yen, Pinchas Cohen, Ram Kannan, David R. Hinton

    Izdano 2016
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  17. 17
    Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells

    Protein polymer nanoparticles engineered as chaperones protect against apoptosis in human retinal pigment epithelial cells od Wan Wang, Parameswaran G. Sreekumar, Vinod Valluripalli, Pu Shi, Jiawei Wang, Yi‐An Lin, Honggang Cui, Ram Kannan, David R. Hinton, J. Andrew MacKay

    Izdano 2014
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  18. 18
    Antiapoptotic Properties of α-Crystallin–Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells

    Antiapoptotic Properties of α-Crystallin–Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells od Parameswaran G. Sreekumar, Paresh P. Chothe, K. Krishna Sharma, Rinku Baid, Uday B. Kompella, Christine Spee, Nandini Kannan, Christina Manh, Stephen J. Ryan, Vadivel Ganapathy, Ram Kannan, David R. Hinton

    Izdano 2013
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