Resultats de la cerca - Panagiotis A. Konstantinopoulos

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  1. 1
    From checkpoint to checkpoint: DNA damage ATR/Chk1 checkpoint signalling elicits PD-L1 immune checkpoint activation

    From checkpoint to checkpoint: DNA damage ATR/Chk1 checkpoint signalling elicits PD-L1 immune checkpoint activation per Kent W. Mouw, Panagiotis A. Konstantinopoulos

    Publicat 2018
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  2. 2
    PARP inhibition and immune modulation: scientific rationale and perspectives for the treatment of gynecologic cancers

    PARP inhibition and immune modulation: scientific rationale and perspectives for the treatment of gynecologic cancers per Elizabeth K. Lee, Panagiotis A. Konstantinopoulos

    Publicat 2020
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  3. 3
    PARP Inhibitors for Ovarian Cancer: Current Indications, Future Combinations, and Novel Assets in Development to Target DNA Damage Repair

    PARP Inhibitors for Ovarian Cancer: Current Indications, Future Combinations, and Novel Assets in Development to Target DNA Damage Repair per Panagiotis A. Konstantinopoulos, Stéphanie Lheureux, Kathleen N. Moore

    Publicat 2020
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  4. 4
    Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis

    Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis per Michalis V. Karamouzis, Panagiotis A. Konstantinopoulos, Athanasios G. Papavassiliou

    Publicat 2007
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  5. 5
    Choosing wisely: Selecting PARP inhibitor combinations to promote anti-tumor immune responses beyond BRCA mutations

    Choosing wisely: Selecting PARP inhibitor combinations to promote anti-tumor immune responses beyond BRCA mutations per Jennifer Veneris, Ursula A. Matulonis, Joyce F. Liu, Panagiotis A. Konstantinopoulos

    Publicat 2019
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  6. 6
    Suberoylanilide hydroxamic acid (SAHA) enhances olaparib activity by targeting homologous recombination DNA repair in ovarian cancer

    Suberoylanilide hydroxamic acid (SAHA) enhances olaparib activity by targeting homologous recombination DNA repair in ovarian cancer per Panagiotis A. Konstantinopoulos, Andrew J. Wilson, Jeanette Saskowski, Erica Wass, Dineo Khabele

    Publicat 2014
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  7. 7
    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer

    Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer per Panagiotis A. Konstantinopoulos, Raphaël Ceccaldi, Geoffrey I. Shapiro, Alan D. D’Andrea

    Publicat 2015
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  8. 8
    Biomarkers of Response and Resistance to DNA Repair Targeted Therapies

    Biomarkers of Response and Resistance to DNA Repair Targeted Therapies per Elizabeth H. Stover, Panagiotis A. Konstantinopoulos, Ursula A. Matulonis, Elizabeth M. Swisher

    Publicat 2016
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  9. 9
    DNA Damage and Repair Biomarkers of Immunotherapy Response

    DNA Damage and Repair Biomarkers of Immunotherapy Response per Kent W. Mouw, Michael S. Goldberg, Panagiotis A. Konstantinopoulos, Alan D. D’Andrea

    Publicat 2017
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  10. 10
    Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates

    Evolutionarily conserved serum microRNAs predict radiation-induced fatality in nonhuman primates per Wojciech Fendler, Beata Małachowska, Khyati Meghani, Panagiotis A. Konstantinopoulos, Chandan Guha, Vijay K. Singh, Dipanjan Chowdhury

    Publicat 2017
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  11. 11
    Phase II study of single-agent cabozantinib in patients with recurrent clear cell ovarian, primary peritoneal or fallopian tube cancer (NRG-GY001)

    Phase II study of single-agent cabozantinib in patients with recurrent clear cell ovarian, primary peritoneal or fallopian tube cancer (NRG-GY001) per Panagiotis A. Konstantinopoulos, William E. Brady, John Farley, Amy E. Armstrong, Denise Uyar, David M. Gershenson

    Publicat 2018
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  12. 12
    Targeted Next-Generation Sequencing Reveals Clinically Actionable <i>BRAF</i> and <i>ESR1</i> Mutations in Low-Grade Serous Ovarian Carcinoma

    Targeted Next-Generation Sequencing Reveals Clinically Actionable <i>BRAF</i> and <i>ESR1</i> Mutations in Low-Grade Serous Ovarian Carcinoma per Elizabeth H. Stover, Colleen M. Feltmate, Ross S. Berkowitz, Neal I. Lindeman, Ursula A. Matulonis, Panagiotis A. Konstantinopoulos

    Publicat 2018
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  13. 13
    MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

    MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability per Young Eun Choi, Yunfeng Pan, Eunmi Park, Panagiotis A. Konstantinopoulos, Subhajyoti De, Alan D. D’Andrea, Dipanjan Chowdhury

    Publicat 2014
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  14. 14
    Resistance to therapy in <i>BRCA2</i> mutant cells due to loss of the nucleosome remodeling factor CHD4

    Resistance to therapy in <i>BRCA2</i> mutant cells due to loss of the nucleosome remodeling factor CHD4 per Shawna Guillemette, Ryan W. Serra, Min Peng, Janelle A. Hayes, Panagiotis A. Konstantinopoulos, Michael R. Green, Sharon B. Cantor

    Publicat 2015
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  15. 15
    Keap1 Mutations and Nrf2 Pathway Activation in Epithelial Ovarian Cancer

    Keap1 Mutations and Nrf2 Pathway Activation in Epithelial Ovarian Cancer per Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Elena Fountzilas, Nancy Francoeur, Srisowmya Sanisetty, Alexandros P. Grammatikos, Jonathan L. Hecht, Stephen A. Cannistra

    Publicat 2011
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  16. 16
    Gene Expression Profile of <i>BRCA</i>ness That Correlates With Responsiveness to Chemotherapy and With Outcome in Patients With Epithelial Ovarian Cancer

    Gene Expression Profile of <i>BRCA</i>ness That Correlates With Responsiveness to Chemotherapy and With Outcome in Patients With Epithelial Ovarian Cancer per Panagiotis A. Konstantinopoulos, Dimitrios Spentzos, Beth Y. Karlan, Toshiyasu Taniguchi, Elena Fountzilas, Nancy Francoeur, Douglas A. Levine, Stephen A. Cannistra

    Publicat 2010
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  17. 17
    PARP Inhibition Induces Enrichment of DNA Repair–Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells

    PARP Inhibition Induces Enrichment of DNA Repair–Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells per Chiara Bellio, Celeste M. DiGloria, Rosemary Foster, Kaitlyn E. James, Panagiotis A. Konstantinopoulos, Whitfield B. Growdon, Bo R. Rueda

    Publicat 2018
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  18. 18
    A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance

    A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance per Raphaël Ceccaldi, Kevin W. O’Connor, Kent W. Mouw, Adam Y. Li, Ursula A. Matulonis, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos

    Publicat 2015
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  19. 19
    Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells

    Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells per Young Eun Choi, Chiara Battelli, Jacqueline Watson, Joyce F. Liu, Jennifer Curtis, Alexander Morse, Ursula A. Matulonis, Dipanjan Chowdhury, Panagiotis A. Konstantinopoulos

    Publicat 2014
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  20. 20
    Complications of pelvic radiation in patients treated for gynecologic malignancies

    Complications of pelvic radiation in patients treated for gynecologic malignancies per Akila N. Viswanathan, Larissa J. Lee, Jairam R. Eswara, Neil S. Horowitz, Panagiotis A. Konstantinopoulos, Kristina Mirabeau-Beale, Brent S. Rose, Arvind von Keudell, Jennifer Y. Wo

    Publicat 2014
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