Ohcanbohtosat - Palomero, Luis

COMP-10. ANTI-CORRELATED TGFβ AND ALTERNATIVE END-JOINING DNA REPAIR SIGNATURES ASSOCIATE WITH OUTCOME IN PRIMARY GBM Dahkki Barcellos-Hoff, Mary, Guix, Ines, Moore, Jade, Pujana, Miquel Angel, Palomero, Luis, Liu, Qi

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Anti-tumor effects of anti-Semaphorin 4D antibody unravel a novel pro-invasive mechanism of vascular targeting agents Dahkki Zuazo-Gaztelu, Iratxe, Pàez-Ribes, Marta, Carrasco, Patricia, Martín, Laura, Soler, Adriana, Martínez-Lozano, Mar, Pons, Roser, Llena, Judith, Palomero, Luis, Graupera, Mariona, Casanovas, Oriol

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NSD2 is a conserved driver of metastatic prostate cancer progression Dahkki Aytes, Alvaro, Giacobbe, Arianna, Mitrofanova, Antonina, Ruggero, Katia, Cyrta, Joanna, Arriaga, Juan, Palomero, Luis, Farran-Matas, Sonia, Rubin, Mark A., Shen, Michael M., Califano, Andrea, Abate-Shen, Cory

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EVI1 as a Prognostic and Predictive Biomarker of Clear Cell Renal Cell Carcinoma Dahkki Palomero, Luis, Bodnar, Lubomir, Mateo, Francesca, Herranz-Ors, Carmen, Espín, Roderic, García-Varelo, Mar, Jesiotr, Marzena, Ruiz de Garibay, Gorka, Casanovas, Oriol, López, José I., Pujana, Miquel Angel

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Kidney cancer PDOXs reveal patient‐specific pro‐malignant effects of antiangiogenics and its molecular traits Dahkki Moserle, Lidia, Pons, Roser, Martínez‐Lozano, Mar, Jiménez‐Valerio, Gabriela A, Vidal, August, Suárez, Cristina, Trilla, Enrique, Jiménez, José, de Torres, Inés, Carles, Joan, Senserrich, Jordi, Aguilar, Susana, Palomero, Luis, Amadori, Alberto, Casanovas, Oriol

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Tumor Expression of Cyclin-Dependent Kinase 5 (Cdk5) Is a Prognostic Biomarker and Predicts Outcome of Oxaliplatin-Treated Metastatic Colorectal Cancer Patients Dahkki Ruiz de Porras, Vicenç, Bystrup, Sara, Cabrero-de las Heras, Sara, Musulén, Eva, Palomero, Luis, Alonso, Maria Henar, Nieto, Rocio, Arango, Diego, Moreno, Víctor, Queralt, Cristina, Manzano, José Luis, Layos, Laura, Bugés, Cristina, Martinez-Balibrea, Eva

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Loss of TGFβ signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types Dahkki Liu, Qi, Palomero, Luis, Moore, Jade, Guix, Ines, Espin, Roderic, Aytés, Alvaro, Mao, Jian-Hua, Paulovich, Amanda G., Whiteaker, Jeffrey R., Ivey, Richard G., Iliakis, George, Luo, Daxian, Chalmers, Anthony J., Murnane, John, Pujana, Miquel Angel, Barcellos-Hoff, Mary Helen

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Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1 Dahkki Roux, Cecilia, Jafari, Soode Moghadas, Shinde, Rahul, Duncan, Gordon, Cescon, David W., Silvester, Jennifer, Chu, Mandy F., Hodgson, Kelsey, Berger, Thorsten, Wakeham, Andrew, Palomero, Luis, Garcia-Valero, Mar, Pujana, Miguel A., Mak, Tak W., McGaha, Tracy L., Cappello, Paola, Gorrini, Chiara

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Taxane-induced attenuation of the CXCR2/BCL-2 axis sensitizes prostate cancer to platinum-based treatment. Dahkki de Porras, Vicenç Ruiz, Wang, Xieng C., Palomero, Luis, Marin-Aguilera, Mercedes, Solé-Blanch, Carme, Indacochea, Alberto, Jimenez, Natalia, Bystrup, Sara, Bakht, Martin, Conteduca, Vincenza, Piulats, Josep M., Buisan, Oscar, Suarez, José F., Pardo, Juan Carlos, Castro, Elena, Olmos, David, Beltran, Himisha, Mellado, Begoña, Martinez-Balibrea, Eva, Font, Albert, Aytes, Alvaro

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Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis Dahkki Li, Li, Guturi, Kiran Kumar Naidu, Gautreau, Brandon, Patel, Parasvi S., Saad, Amine, Morii, Mayako, Mateo, Francesca, Palomero, Luis, Barbour, Haithem, Gomez, Antonio, Ng, Deborah, Kotlyar, Max, Pastrello, Chiara, Jackson, Hartland W., Khokha, Rama, Jurisica, Igor, Affar, El Bachir, Raught, Brian, Sanchez, Otto, Alaoui-Jamali, Moulay, Pujana, Miguel A., Hakem, Anne, Hakem, Razq

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Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis Dahkki Li, Li, Guturi, Kiran Kumar Naidu, Gautreau, Brandon, Patel, Parasvi S., Saad, Amine, Morii, Mayako, Mateo, Francesca, Palomero, Luis, Barbour, Haithem, Gomez, Antonio, Ng, Deborah, Kotlyar, Max, Pastrello, Chiara, Jackson, Hartland W., Khokha, Rama, Jurisica, Igor, Affar, El Bachir, Raught, Brian, Sanchez, Otto, Alaoui-Jamali, Moulay, Pujana, Miguel A., Hakem, Anne, Hakem, Razq

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Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance Dahkki Ruiz de Garibay, Gorka, Mateo, Francesca, Stradella, Agostina, Valdés-Mas, Rafael, Palomero, Luis, Serra-Musach, Jordi, Puente, Diana A., Díaz-Navarro, Ander, Vargas-Parra, Gardenia, Tornero, Eva, Morilla, Idoia, Farré, Lourdes, Martinez-Iniesta, María, Herranz, Carmen, McCormack, Emmet, Vidal, August, Petit, Anna, Soler, Teresa, Lázaro, Conxi, Puente, Xose S., Villanueva, Alberto, Pujana, Miguel Angel

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Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors Dahkki Lahiguera, Álvaro, Hyroššová, Petra, Figueras, Agnès, Garzón, Diana, Moreno, Roger, Soto‐Cerrato, Vanessa, McNeish, Iain, Serra, Violeta, Lazaro, Conxi, Barretina, Pilar, Brunet, Joan, Menéndez, Javier, Matias‐Guiu, Xavier, Vidal, August, Villanueva, Alberto, Taylor‐Harding, Barbie, Tanaka, Hisashi, Orsulic, Sandra, Junza, Alexandra, Yanes, Oscar, Muñoz‐Pinedo, Cristina, Palomero, Luís, Pujana, Miquel Àngel, Perales, José Carlos, Viñals, Francesc

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Chromosome 12p amplification in triple-negative/BRCA1-mutated breast cancer associates with emergence of docetaxel resistance and carboplatin sensitivity Dahkki Gómez-Miragaya, Jorge, Díaz-Navarro, Ander, Tonda, Raul, Beltran, Sergi, Palomero, Luis, Palafox, Marta, Dobrolecki, Lacey E., Huang, Chen, Vasaikar, Suhas, Zhang, Bing, Wulf, Gerburg M., Collado-Sole, Alejandro, Trinidad, Eva M, Muñoz, Purificación, Paré, Laia, Prat, Aleix, Bruna, Alejandra, Caldas, Carlos, Arribas, Joaquín, Soler-Monso, María Teresa, Petit, Anna, Balmaña, Judith, Cruz, Cristina, Serra, Violeta, Pujana, Miguel Angel, Lewis, Michael T., Puente, Xose S., González-Suárez, Eva

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Immune Cell Associations with Cancer Risk Dahkki Palomero, Luis, Galván-Femenía, Ivan, de Cid, Rafael, Espín, Roderic, Barnes, Daniel R., CIMBA, Blommaert, Eline, Gil-Gil, Miguel, Falo, Catalina, Stradella, Agostina, Ouchi, Dan, Roso-Llorach, Albert, Violan, Concepció, Peña-Chilet, María, Dopazo, Joaquín, Extremera, Ana Isabel, García-Valero, Mar, Herranz, Carmen, Mateo, Francesca, Mereu, Elisabetta, Beesley, Jonathan, Chenevix-Trench, Georgia, Roux, Cecilia, Mak, Tak, Brunet, Joan, Hakem, Razq, Gorrini, Chiara, Antoniou, Antonis C., Lázaro, Conxi, Pujana, Miquel Angel

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RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors Dahkki Patel, Parasvi S., Abraham, Karan Joshua, Guturi, Kiran Kumar Naidu, Halaby, Marie-Jo, Khan, Zahra, Palomero, Luis, Ho, Brandon, Duan, Shili, St-Germain, Jonathan, Algouneh, Arash, Mateo, Francesca, El Ghamrasni, Samah, Barbour, Haithem, Barnes, Daniel R., Beesley, Jonathan, Sanchez, Otto, Berman, Hal K., Brown, Grant W., El Bachir Affar, Chenevix-Trench, Georgia, Antoniou, Antonis C., Arrowsmith, Cheryl H., Raught, Brian, Pujana, Miquel Angel, Mekhail, Karim, Hakem, Anne, Hakem, Razqallah

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Modification of BRCA1-associated breast cancer risk by HMMR overexpression Dahkki Mateo, Francesca, He, Zhengcheng, Mei, Lin, de Garibay, Gorka Ruiz, Herranz, Carmen, García, Nadia, Lorentzian, Amanda, Baiges, Alexandra, Blommaert, Eline, Gómez, Antonio, Mirallas, Oriol, Garrido-Utrilla, Anna, Palomero, Luis, Espín, Roderic, Extremera, Ana I., Soler-Monsó, M. Teresa, Petit, Anna, Li, Rong, Brunet, Joan, Chen, Ke, Tan, Susanna, Eaves, Connie J., McCloskey, Curtis, Hakem, Razq, Khokha, Rama, Lange, Philipp F., Lázaro, Conxi, Maxwell, Christopher A., Pujana, Miquel Angel

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AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer Dahkki Kubli, Shawn P., Bassi, Christian, Roux, Cecilia, Wakeham, Andrew, Göbl, Christoph, Zhou, Wenjing, Jafari, Soode Moghadas, Snow, Bryan, Jones, Lisa, Palomero, Luis, Thu, Kelsie L., Cassetta, Luca, Soong, Daniel, Berger, Thorsten, Ramachandran, Parameswaran, Baniasadi, Shakiba P., Duncan, Gordon, Lindzen, Moshit, Yarden, Yosef, Herranz, Carmen, Lazaro, Conxi, Chu, Mandy F., Haight, Jillian, Tinto, Paul, Silvester, Jennifer, Cescon, David W., Petit, Anna, Pettersson, Sven, Pollard, Jeffrey W., Mak, Tak W., Pujana, Miguel A., Cappello, Paola, Gorrini, Chiara

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Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis Dahkki Herranz, Carmen, Mateo, Francesca, Baiges, Alexandra, Ruiz de Garibay, Gorka, Junza, Alexandra, Johnson, Simon R, Miller, Suzanne, García, Nadia, Capellades, Jordi, Gómez, Antonio, Vidal, August, Palomero, Luis, Espín, Roderic, Extremera, Ana I, Blommaert, Eline, Revilla‐López, Eva, Saez, Berta, Gómez‐Ollés, Susana, Ancochea, Julio, Valenzuela, Claudia, Alonso, Tamara, Ussetti, Piedad, Laporta, Rosalía, Xaubet, Antoni, Rodríguez‐Portal, José A, Montes‐Worboys, Ana, Machahua, Carlos, Bordas, Jaume, Menendez, Javier A, Cruzado, Josep M, Guiteras, Roser, Bontoux, Christophe, La Motta, Concettina, Noguera‐Castells, Aleix, Mancino, Mario, Lastra, Enrique, Rigo‐Bonnin, Raúl, Perales, Jose C, Viñals, Francesc, Lahiguera, Alvaro, Zhang, Xiaohu, Cuadras, Daniel, van Moorsel, Coline H M, van der Vis, Joanne J, Quanjel, Marian J R, Filippakis, Harilaos, Hakem, Razq, Gorrini, Chiara, Ferrer, Marc, Ugun‐Klusek, Aslihan, Billett, Ellen, Radzikowska, Elżbieta, Casanova, Álvaro, Molina‐Molina, María, Roman, Antonio, Yanes, Oscar, Pujana, Miquel A

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