Sökresultat - Pacold, Michael

Yeast N-glycanase distinguishes between native and non-native glycoproteins av Hirsch, Christian, Misaghi, Shahram, Blom, Daniël, Pacold, Michael E, Ploegh, Hidde L

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Brakes and gas pedals: Meeting: Spetses 2000, molecular mechanisms of development and disease av Clapier, Cedric R., Boer, Jasper de, Pacold, Michael E., Tamme, Richard, van Dinten, Leonie C.

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Slow Self-Activation Enhances The Potency of Virdin Prodrugs av Blois, Joseph, Yuan, Hushan, Smith, Adam, Pacold, Michael, Weissleder, Ralph, Cantley, Lewis C., Josephson, Lee

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Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain av Chantranupong, Lynne, Saulnier, Jessica L, Wang, Wengang, Jones, Drew R, Pacold, Michael E, Sabatini, Bernardo L

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The Polar Oxy-metabolome Reveals the 4-Hydroxymandelate CoQ10 Synthesis Pathway av Banh, Robert S., Kim, Esther S., Spillier, Quentin, Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Shi, Guangbin, Jones, Drew R., Kimmelman, Alec C., Pacold, Michael E.

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mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin av Kang, Seong A., Pacold, Michael E., Cervantes, Christopher L., Lim, Daniel, Lou, Hua Jane, Ottina, Kathleen, Gray, Nathanael S., Turk, Benjamin E., Yaffe, Michael B., Sabatini, David M.

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Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery av Karve, Shrirang, Werner, Michael E., Sukumar, Rohit, Cummings, Natalie D., Copp, Jonathan A., Wang, Edina C., Li, Chenxi, Sethi, Manish, Chen, Ronald C., Pacold, Michael E., Wang, Andrew Z.

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Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer av Banh, Robert S., Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Walters, Beth, Kuljanin, Miljan, Gikandi, Ajami, Wang, Huamin, Mancias, Joseph D., Schneider, Robert J., Pacold, Michael E., Kimmelman, Alec C.

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SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism av Kory, Nora, Wyant, Gregory A., Prakash, Gyan, de Bos, Jelmi uit, Bottanelli, Francesca, Pacold, Michael E., Chan, Sze Ham, Lewis, Caroline A., Wang, Tim, Keys, Heather R., Guo, Yang Eric, Sabatini, David M.

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Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes av Shah, Ravi, Murthy, Venkatesh, Pacold, Michael, Danielson, Kirsty, Tanriverdi, Kahraman, Larson, Martin G., Hanspers, Kristina, Pico, Alexander, Mick, Eric, Reis, Jared, de Ferranti, Sarah, Freinkman, Elizaveta, Levy, Daniel, Hoffmann, Udo, Osganian, Stavroula, Das, Saumya, Freedman, Jane E.

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Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors av Rohde, Jason M., Brimacombe, Kyle R., Liu, Li, Pacold, Michael E., Yasgar, Adam, Cheff, Dorian M., Lee, Tobie D., Rai, Ganesha, Baljinnyam, Bolormaa, Li, Zhuyin, Simeonov, Anton, Hall, Matthew D., Shen, Min, Sabatini, David M., Boxer, Matthew B.

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Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition av Shaul, Yoav D, Freinkman, Elizaveta, Comb, William C, Cantor, Jason R, Tam, Wai Leong, Thiru, Prathapan, Kim, Dohoon, Kanarek, Naama, Pacold, Michael E, Chen, Walter W, Bierie, Brian, Possemato, Richard, Reinhardt, Ferenc, Weinberg, Robert A, Yaffe, Michael B, Sabatini, David M

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Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor av Lim, Sang Min, Westover, Kenneth D., Ficarro, Scott B., Harrison, Rane A., Choi, Hwan Geun, Pacold, Michael E., Carrasco, Martin, Hunter, John, Kim, Nam Doo, Xie, Ting, Sim, Taebo, Jänne, Pasi A., Meyerson, Matthew, Marto, Jarrod A., Engen, John R., Gray, Nathanael S.

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Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy av Wu, Lin, Hollinshead, Kate E.R., Hao, Yuhan, Au, Christy, Kroehling, Lina, Ng, Charles, Lin, Woan-Yu, Li, Dayi, Silva, Hernandez Moura, Shin, Jong, Lafaille, Juan J., Possemato, Richard, Pacold, Michael E., Papagiannakopoulos, Thales, Kimmelman, Alec C., Satija, Rahul, Littman, Dan R.

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Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5’ sites av Schwartz, Schraga, Mumbach, Maxwell R., Jovanovic, Marko, Wang, Tim, Maciag, Karolina, Bushkin, G. Guy, Mertins, Philipp, Ter-Ovanesyan, Dmitry, Habib, Naomi, Cacchiarelli, Davide, Sanjana, Neville E., Freinkman, Elizaveta, Pacold, Michael E., Satija, Rahul, Mikkelsen, Tarjei S., Hacohen, Nir, Zhang, Feng, Carr, Steven A., Lander, Eric S., Regev, Aviv

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SHMT2 drives glioma cell survival in the tumor microenvironment but imposes a dependence on glycine clearance av Kim, Dohoon, Fiske, Brian P., Birsoy, Kivanc, Freinkman, Elizaveta, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael E., Chen, Walter W., Cantor, Jason R., Shelton, Laura M., Gui, Dan Y., Kwon, Manjae, Ramkissoon, Shakti H., Ligon, Keith L., Kang, Seong Woo, Snuderl, Matija, Heiden, Matthew G. Vander, Sabatini, David M.

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PIK3CA mutant tumors depend on oxoglutarate dehydrogenase av Ilic, Nina, Birsoy, Kıvanç, Aguirre, Andrew J., Kory, Nora, Pacold, Michael E., Singh, Shambhavi, Moody, Susan E., DeAngelo, Joseph D., Spardy, Nicole A., Freinkman, Elizaveta, Weir, Barbara A., Tsherniak, Aviad, Cowley, Glenn S., Root, David E., Asara, John M., Vazquez, Francisca, Widlund, Hans R., Sabatini, David M., Hahn, William C.

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The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signaling av Floyd, Scott R., Pacold, Michael E., Huang, Qiuying, Clarke, Scott M., Lam, Fred C., Cannell, Ian G., Bryson, Bryan D., Rameseder, Jonathan, Lee, Michael J., Blake, Emily J., Fydrych, Anna, Ho, Richard, Greenberger, Benjamin A., Chen, Grace C., Maffa, Amanda, Del Rosario, Amanda M., Root, David E., Carpenter, Anne E., Hahn, William C., Sabatini, David M., Chen, Clark C., White, Forest M., Bradner, James E., Yaffe, Michael B.

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DDRE-22. TARGETING SERINE SYNTHESIS IN BRAIN METASTASIS av Ngo, Bryan, Kim, Eugenie, Osorio-Vasquez, Victoria, Doll, Sophia, Bustraan, Sophia, Liang, Roger, Luengo, Alba, Davidson, Shawn, Ali, Ahmed, Ferraro, Gino, Fischer, Grant, Plasger, Ariana, Rajasekhar, Vinagolu, Kastenhuber, Edward, Eskandari, Roozbeh, Bacha, Sarah, Sriram, Roshan, Bakhoum, Samuel, Snuderl, Matija, Cotzia, Paolo, Healey, John, Sabatini, David, Jones, Drew, Zhao, Jean, Yu, Min, Jain, Rakesh, Keshari, Kayvan, Davies, Michael, Heiden, Matthew Vander, Hernando, Eva, Mann, Matthias, Cantley, Lewis, Pacold, Michael

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Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer av Possemato, Richard, Marks, Kevin M., Shaul, Yoav D., Pacold, Michael E., Kim, Dohoon, Birsoy, Kivanç, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing, Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Sabatini, David M.

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