Search Results - Olle Sangfelt

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  1. 1
    Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

    Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer by Shahab Akhoondi, Linda S. Lindström, Martin Widschwendter, Martin Corcoran, Jonas Bergh, Charles Spruck, Dan Grandér, Olle Sangfelt

    Published 2010
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  2. 2
    Ubiquitylation of Cyclin E Requires the Sequential Function of SCF Complexes Containing Distinct hCdc4 Isoforms

    Ubiquitylation of Cyclin E Requires the Sequential Function of SCF Complexes Containing Distinct hCdc4 Isoforms by Frank van Drogen, Olle Sangfelt, Alena Malyukova, Liudmila Matskova, Elizabeth S. Yeh, Anthony R. Means, Steven I. Reed

    Published 2006
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  3. 3
    Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis

    Ablation of Key Oncogenic Pathways by RITA-Reactivated p53 Is Required for Efficient Apoptosis by Vera Grinkevich, Fedor Nikulenkov, Yao Shi, Martin Enge, Wenjie Bao, Alena Maljukova, Angela Gluch, Alexander Kel, Olle Sangfelt, Galina Selivanova

    Published 2009
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  4. 4
    The RBCC Gene<i>RFP2</i>(<i>Leu5</i>) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD

    The RBCC Gene<i>RFP2</i>(<i>Leu5</i>) Encodes a Novel Transmembrane E3 Ubiquitin Ligase Involved in ERAD by Mikael Lerner, Martin Corcoran, Diana Cepeda, Michael L. Nielsen, Roman A. Zubarev, Fredrik Pontén, Mathias Uhlén, Sophia Hober, Dan Grandér, Olle Sangfelt

    Published 2007
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  5. 5
    The Tumor Suppressor Gene <i>hCDC4</i> Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia with Functional Consequences for Notch Signaling

    The Tumor Suppressor Gene <i>hCDC4</i> Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia with Functional Consequences for Notch Signaling by Alena Malyukova, Takeaki Dohda, Natalie von der Lehr, Shahab Akhondi, Martin Corcoran, Mats Heyman, Charles Spruck, Dan Grandér, Urban Lendahl, Olle Sangfelt

    Published 2007
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  6. 6
    MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

    MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression by Mikael Lerner, Josefin Lundgren, Shahab Akhoondi, Angelina Jahn, Hwee‐Fang Ng, Farhad Akbari Moqadam, Joachim A.F. Oude Vrielink, Reuven Agami, Monique L. den Boer, Dan Grandér, Olle Sangfelt

    Published 2011
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  7. 7
    Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase

    Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase by Ajay A. Vashisht, Kimberly B. Zumbrennen, Xinhua Huang, David N. Powers, Armando Durazo, Dahui Sun, Nimesh Bhaskaran, Anja Persson, Mathias Uhlén, Olle Sangfelt, Charles Spruck, Elizabeth A. Leibold, James A. Wohlschlegel

    Published 2009
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  8. 8
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells by Jia Shen, Zhixin Qiu, Qiulian Wu, Darren Finlay, Guillermina Garcia, Dahui Sun, Juha Rantala, William D. Barshop, Jennifer L. Hope, Ryan C. Gimple, Olle Sangfelt, Linda M. Bradley, James A. Wohlschlegel, Jeremy N. Rich, Charles Spruck

    Published 2020
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  9. 9
    Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

    Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway by Azadeh Arabi, Karim Ullah, Rui M. Branca, Johan R. Johansson, Daniel Bandarra, Moritz Haneklaus, Jing Fu, Ingrid M. Ariës, Peter Nilsson, Monique L. den Boer, Katja Pokrovskaja Tamm, Dan Grandér, Gutian Xiao, Sónia Rocha, Janne Lehtiö, Olle Sangfelt

    Published 2012
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  10. 10
    Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities

    Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcr... by Juha Mehtonen, Susanna Teppo, Mari Lahnalampi, Aleksi Kokko, Riina Kaukonen, Laura Oksa, Maria Bouvy‐Liivrand, Alena Malyukova, Artturi Mäkinen, Saara Laukkanen, Petri I. Mäkinen, Samuli Rounioja, Pekka Ruusuvuori, Olle Sangfelt, Riikka Lund, Tapio Lönnberg, Olli Lohi, Merja Heinäniemi

    Published 2020
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  11. 11
    FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

    FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma by Aldwin Suryo Rahmanto, Vasil Savov, Andrä Brunner, Sara Bolin, Holger Weishaupt, Alena Malyukova, Gabriela Rosén, Matko Čančer, Sonja Hutter, Anders Sundström, Daisuke Kawauchi, David Jones, Charles Spruck, Michael D. Taylor, Yoon‐Jae Cho, Stefan M. Pfister, Marcel Kool, Andrey Korshunov, Fredrik J. Swartling, Olle Sangfelt

    Published 2016
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  12. 12
    <i>FBXW7/hCDC4</i> Is a General Tumor Suppressor in Human Cancer

    <i>FBXW7/hCDC4</i> Is a General Tumor Suppressor in Human Cancer by Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dofou, Christian Marth, Elisabeth Mueller‐Holzner, Martin Corcoran, Markus Dagnell, Sepideh Zabihi Nejad, Babak Noori Nayer, Mohammad Reza Zali, Johan Hansson, Susanne Egyhazi, Fredrik Petersson, Per Sangfelt, Hans Nordgren, Dan Grandér, Steven I. Reed, Martin Widschwendter, Olle Sangfelt, Charles Spruck

    Published 2007
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  13. 13
    <scp>CDK</scp>‐mediated activation of the <scp>SCF<sup>FBXO</sup></scp><sup>28</sup> ubiquitin ligase promotes <scp>MYC</scp>‐driven transcription and tumourigenesis and predicts poor survival in breast cancer

    <scp>CDK</scp>‐mediated activation of the <scp>SCF<sup>FBXO</sup></scp><sup>28</sup> ubiquitin ligase promotes <scp>MYC</scp>‐driven transcription and tumourigenesis and predicts p... by Diana Cepeda, Hwee‐Fang Ng, H R Sharifi, Salah Mahmoudi, Vanessa Soto‐Cerrato, Erik Fredlund, Kristina Magnusson, Helén Nilsson, Alena Malyukova, Juha Rantala, Daniel Klevebring, Francesc Viñals, Nimesh Bhaskaran, Siti Mariam Zakaria, Aldwin Suryo Rahmanto, Stefan Grotegut, Michael L. Nielsen, Cristina Al‐Khalili Szigyarto, Dahui Sun, Mikael Lerner, Sanjay Navani, Martin Widschwendter, Mathias Uhlén, Karin Jirström, Fredrik Pontén, James A. Wohlschlegel, Dan Grandér, Charles Spruck, Lars‐Gunnar Larsson, Olle Sangfelt

    Published 2013
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