Výsledky vyhledávání - Olga I. Gan

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  1. 1
    Differential Maintenance of Primitive Human SCID-Repopulating Cells, Clonogenic Progenitors, and Long-Term Culture-Initiating Cells After Incubation on Human Bone Marrow Stromal Cells

    Differential Maintenance of Primitive Human SCID-Repopulating Cells, Clonogenic Progenitors, and Long-Term Culture-Initiating Cells After Incubation on Human Bone Marrow Stromal Ce... Autor Olga I. Gan, Barbara Murdoch, André Larochelle, John E. Dick

    Vydáno 1997
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  2. 2
    Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells

    Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells Autor Joby L. McKenzie, Olga I. Gan, Monica Doedens, John E. Dick

    Vydáno 2005
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  3. 3
    Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment

    Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment Autor Frédéric Mazurier, Olga I. Gan, Joby L. McKenzie, Monica Doedens, John E. Dick

    Vydáno 2003
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  4. 4
    Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin−CD34+CD38− population

    Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin−CD34+CD38− population Autor Joby L. McKenzie, Katsuto Takenaka, Olga I. Gan, Monica Doedens, John E. Dick

    Vydáno 2006
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  5. 5
    Bone Marrow Failure in the Fanconi Anemia Group C Mouse Model After DNA Damage

    Bone Marrow Failure in the Fanconi Anemia Group C Mouse Model After DNA Damage Autor Madeleine Carreau, Olga I. Gan, Lili Liu, Monica Doedens, Colin McKerlie, John E. Dick, Manuel Buchwald

    Vydáno 1998
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  6. 6
    Transduction of Human CD34+CD38- Bone Marrow and Cord Blood-Derived SCID-Repopulating Cells with Third-Generation Lentiviral Vectors

    Transduction of Human CD34+CD38- Bone Marrow and Cord Blood-Derived SCID-Repopulating Cells with Third-Generation Lentiviral Vectors Autor Guillermo Güenechea, Olga I. Gan, Takeshi Inamitsu, Craig Dorrell, Daniel S. Pereira, Michael T. Kelly, Luigi Naldini, John E. Dick

    Vydáno 2000
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  7. 7
    Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells

    Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells Autor Elvin Wagenblast, Maria Azkanaz, Sabrina Smith, Lorien Shakib, Jessica McLeod, Gabriela Krivdova, Joana Araújo, Leonard D. Shultz, Olga I. Gan, John E. Dick, Eric R. Lechman

    Vydáno 2019
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  8. 8
    A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal

    A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal Autor Michael Milyavsky, Olga I. Gan, Magan Trottier, Martin Komosa, Ofer Tabach, Faiyaz Notta, Eric R. Lechman, Karin G. Hermans, Kolja Eppert, Zhanna Konovalova, Olga Ornatsky, Eytan Domany, M. Stephen Meyn, John E. Dick

    Vydáno 2010
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  9. 9
    Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

    Distinct routes of lineage development reshape the human blood hierarchy across ontogeny Autor Faiyaz Notta, Sasan Zandi, Naoya Takayama, Stephanie M. Dobson, Olga I. Gan, Gavin W. Wilson, Kerstin B. Kaufmann, Jessica McLeod, Elisa Laurenti, Cyrille F. Dunant, John D. McPherson, Lincoln Stein, Yigal Dror, John E. Dick

    Vydáno 2015
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  10. 10
    Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

    Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer Autor Antonija Kreso, Catherine O’Brien, Peter van Galen, Olga I. Gan, Faiyaz Notta, Andrew Brown, K.T. Ng, Jing Ma, Erno Wienholds, Cyrille F. Dunant, Aaron Pollett, Steven Gallinger, John D. McPherson, Charles G. Mullighan, Darryl Shibata, John E. Dick

    Vydáno 2012
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  11. 11
    A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness

    A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness Autor Kerstin B. Kaufmann, Andy G.X. Zeng, Étienne Coyaud, Laura García‐Prat, Efthymia Papalexi, Alex Murison, Estelle Laurent, Michelle Chan‐Seng‐Yue, Olga I. Gan, Kristele Pan, Jessica McLeod, Héléna Boutzen, Sasan Zandi, Shin‐ichiro Takayanagi, Rahul Satija, Brian Raught, Stephanie Z. Xie, John E. Dick

    Vydáno 2021
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  12. 12
    Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

    Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal Autor Stephanie Z. Xie, Laura García‐Prat, Véronique Voisin, Robin Ferrari, Olga I. Gan, Elvin Wagenblast, Kerstin B. Kaufmann, Andy G.X. Zeng, Shin‐ichiro Takayanagi, Ishita Patel, Esther K. Lee, Joseph Jargstorf, Gareth D. Holmes, Guy Romm, Kristele Pan, Michelle Shoong, Aditi Vedi, Chiara Luberto, Mark D. Minden, Gary D. Bader, Elisa Laurenti, John E. Dick

    Vydáno 2019
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  13. 13
    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

    TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate Autor Laura García‐Prat, Kerstin B. Kaufmann, Florin Schneiter, Véronique Voisin, Alex Murison, Jocelyn Chen, Michelle Chan‐Seng‐Yue, Olga I. Gan, Jessica McLeod, Sabrina Smith, Michelle Shoong, Darrien Parris, Kristele Pan, Andy G.X. Zeng, Gabriela Krivdova, Kinam Gupta, Shin‐ichiro Takayanagi, Elvin Wagenblast, Weijia Wang, Mathieu Lupien, Timm Schroeder, Stephanie Z. Xie, John E. Dick

    Vydáno 2021
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  14. 14
    FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

    FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells Autor Joana Araújo, Elvin Wagenblast, Véronique Voisin, Jessica McLeod, Olga I. Gan, Suraj Bansal, Liqing Jin, Amanda Mitchell, Blaise Gratton, Sarah K. Cutting, Andrea Arruda, Monica Doedens, Anthea Travas, Dennis Dong Hwan Kim, José‐Mario Capo‐Chichi, Sagi Abelson, Mark D. Minden, Jean Wang, Manuel Sobrinho Simões, Perpétua Pinto‐do‐Ó, Eric R. Lechman, John E. Dick

    Vydáno 2025
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  15. 15
    Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia

    Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia Autor Jaeseung Kim, Michelle Chan‐Seng‐Yue, Sabrina Ge, Andy G.X. Zeng, K.T. Ng, Olga I. Gan, Laura García‐Prat, Eugenia Flores‐Figueroa, Tristan Woo, Amy Xin Wei Zhang, Andrea Arruda, Shivapriya Chithambaram, Stephanie M. Dobson, Amanda Khoo, Shahbaz Khan, Narmin Ibrahimova, Ann George, Anne Tierens, Johann Hitzler, Thomas Kislinger, John E. Dick, John D. McPherson, Mark D. Minden, Faiyaz Notta

    Vydáno 2023
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  16. 16
    The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization

    The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization Autor Naoya Takayama, Alex Murison, Shin‐ichiro Takayanagi, Christopher Arlidge, Stanley Zhou, Laura García‐Prat, Michelle Chan‐Seng‐Yue, Sasan Zandi, Olga I. Gan, Héléna Boutzen, Kerstin B. Kaufmann, Aaron C. Trotman-Grant, Erwin M. Schoof, Ken J. Kron, Noèlia Díaz, John J. Y. Lee, Tiago da Silva Medina, Daniel D. De Carvalho, Michael D. Taylor, Juan M. Vaquerizas, Stephanie Z. Xie, John E. Dick, Mathieu Lupien

    Vydáno 2020
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  17. 17
    Mapping the cellular origin and early evolution of leukemia in Down syndrome

    Mapping the cellular origin and early evolution of leukemia in Down syndrome Autor Elvin Wagenblast, Joana Araújo, Olga I. Gan, Sarah K. Cutting, Alex Murison, Gabriela Krivdova, Maria Azkanaz, Jessica McLeod, Sabrina Smith, Blaise Gratton, Sajid A. Marhon, Martino Gabra, Jessie J.F. Medeiros, Sanaz Manteghi, Jian Chen, Michelle Chan‐Seng‐Yue, Laura García‐Prat, Leonardo Salmena, Daniel D. De Carvalho, Sagi Abelson, Mohamed Abdelhaleem, Karen Chong, Maian Roifman, Patrick Shannon, Jean Wang, Johann Hitzler, David Chitayat, John E. Dick, Eric R. Lechman

    Vydáno 2021
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  18. 18
    Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors

    Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors Autor Edyta E. Wojtowicz, Eric R. Lechman, Karin G. Hermans, Erwin M. Schoof, Erno Wienholds, Ruth Isserlin, Peter A. van Veelen, Mathilde Broekhuis, George M. C. Janssen, Aaron C. Trotman-Grant, Stephanie M. Dobson, Gabriela Krivdova, Jantje Elzinga, Theodore A. Kennedy, Olga I. Gan, Ankit Sinha, Vladimir Ignatchenko, Thomas Kislinger, Bertien Dethmers-Ausema, Ellen Weersing, Mir Farshid Alemdehy, Hans W. J. de Looper, Gary D. Bader, Martha Ritsema, Stefan J. Erkeland, Leonid Bystrykh, John E. Dick, Gerald de Haan

    Vydáno 2016
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  19. 19
    Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation

    Sphingosine-1-Phosphate Receptor 3 Potentiates Inflammatory Programs in Normal and Leukemia Stem Cells to Promote Differentiation Autor Stephanie Z. Xie, Kerstin B. Kaufmann, Weijia Wang, Michelle Chan‐Seng‐Yue, Olga I. Gan, Elisa Laurenti, Laura García‐Prat, Shin‐ichiro Takayanagi, Stanley Ng, Changjiang Xu, Andy G.X. Zeng, Liqing Jin, Jessica McLeod, Elvin Wagenblast, Amanda Mitchell, James A. Kennedy, Qiang Liu, Héléna Boutzen, Melissa Kleinau, Joseph Jargstorf, Gareth D. Holmes, Yang Zhang, Véronique Voisin, Gary D. Bader, Jean Wang, Yusuf A. Hannun, Chiara Luberto, Timm Schroeder, Mark D. Minden, John E. Dick

    Vydáno 2020
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  20. 20
    Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

    Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs Autor Stephanie M. Dobson, Laura García‐Prat, Robert J. Vanner, Jeffrey A. Wintersinger, Esmé Waanders, Zhaohui Gu, Jessica McLeod, Olga I. Gan, Ildiko Grandal, Debbie Payne-Turner, Michael N. Edmonson, Xiaotu Ma, Yiping Fan, Véronique Voisin, Michelle Chan‐Seng‐Yue, Stephanie Z. Xie, Mohsen Hosseini, Sagi Abelson, Pankaj Gupta, Michael Rusch, Ying Shao, Scott R. Olsen, Geoffrey Neale, Steven M. Chan, Gary D. Bader, John Easton, Cynthia J. Guidos, Jayne S. Danska, Jinghui Zhang, Mark D. Minden, Quaid Morris, Charles G. Mullighan, John E. Dick

    Vydáno 2020
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