檢索結果 - Olaf van Tellingen

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  1. 1
    Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

    Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure 由 Johan W. Smit, Maarten T. Huisman, Olaf van Tellingen, Hugh Wiltshire, Alfred H. Schinkel

    出版 1999
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  2. 2
    Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

    Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein 由 Judith van Asperen, Olaf van Tellingen, Frank Tijssen, Alfred H. Schinkel, Jos H. Beijnen

    出版 1998
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  3. 3
    <scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors

    <scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors 由 Ping Zhang, Mark C. de Gooijer, Levi C.M. Buil, Jos H. Beijnen, Gang Li, Olaf van Tellingen

    出版 2015
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  4. 4
    The G2 checkpoint—a node‐based molecular switch

    The G2 checkpoint—a node‐based molecular switch 由 Mark C. de Gooijer, Arnout van den Top, Irena Bočkaj, Jos H. Beijnen, Thomas Würdinger, Olaf van Tellingen

    出版 2017
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  5. 5
    The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors

    The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors 由 Mark C. de Gooijer, Ping Zhang, Ruud Weijer, Levi C.M. Buil, Jos H. Beijnen, Olaf van Tellingen

    出版 2017
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  6. 6
    Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833

    Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833 由 Judith van Asperen, Olaf van Tellingen, Alex Sparreboom, Alfred H. Schinkel, Piet Borst, W J Nooijen, Jos H. Beijnen

    出版 1997
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  7. 7
    Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients

    Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients 由 Olaf van Tellingen, Manon Huizing, Vinodh R. Nannan Panday, J. H. M. Schellens, W J Nooijen, Jos H. Beijnen

    出版 1999
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  8. 8
    P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 Determine the Pharmacokinetics of Etoposide

    P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 Determine the Pharmacokinetics of Etoposide 由 Jurjen S. Lagas, Fan Lin, Els Wagenaar, Maria L.H. Vlaming, Olaf van Tellingen, Jos H. Beijnen, Alfred H. Schinkel

    出版 2009
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  9. 9
    Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma

    Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma 由 Sophia W.M. Bruggeman, Danielle Hulsman, Ellen Tanger, Tessa Buckle, Marleen Blom, John Zevenhoven, Olaf van Tellingen, Maarten van Lohuizen

    出版 2007
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  10. 10
    Abcc4 Together with Abcb1 and Abcg2 Form a Robust Cooperative Drug Efflux System That Restricts the Brain Entry of Camptothecin Analogues

    Abcc4 Together with Abcb1 and Abcg2 Form a Robust Cooperative Drug Efflux System That Restricts the Brain Entry of Camptothecin Analogues 由 Fan Lin, Serena Marchetti, Dick Pluim, Dilek Iusuf, Roberto Mazzanti, Jan H.M. Schellens, Jos H. Beijnen, Olaf van Tellingen

    出版 2013
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  11. 11
    Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness

    Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness 由 Nora Pencheva, Mark C. de Gooijer, Daniël J. Vis, Lodewyk F.A. Wessels, Tom Würdinger, Olaf van Tellingen, René Bernards

    出版 2017
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  12. 12
    Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate <i>in vivo</i>

    Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate <i>in vivo</i> 由 Maria L.H. Vlaming, Anita van Esch, Zeliha Pala, Els Wagenaar, Koen van de Wetering, Olaf van Tellingen, Alfred H. Schinkel

    出版 2009
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  13. 13
    Buparlisib is a brain penetrable pan-PI3K inhibitor

    Buparlisib is a brain penetrable pan-PI3K inhibitor 由 Mark C. de Gooijer, Ping Zhang, Levi C.M. Buil, Ceren H. Çitirikkaya, Nishita Thota, Jos H. Beijnen, Olaf van Tellingen

    出版 2018
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  14. 14
    Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2

    Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2 由 Mark C. de Gooijer, Nienke A. de Vries, Tessa Buckle, Levi C.M. Buil, Jos H. Beijnen, Willem Boogerd, Olaf van Tellingen

    出版 2018
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  15. 15
    ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost

    ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost 由 Mark C. de Gooijer, E. Marleen Kemper, Levi C.M. Buil, Ceren H. Çitirikkaya, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen

    出版 2021
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  16. 16
    The impact of ATP-binding cassette transporters in the diseased brain: Context matters

    The impact of ATP-binding cassette transporters in the diseased brain: Context matters 由 Chrysiida Baltira, Eleonora Aronica, William F. Elmquist, Oliver Langer, Wolfgang Löscher, Jann N. Sarkaria, Pieter Wesseling, Mark C. de Gooijer, Olaf van Tellingen

    出版 2024
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  17. 17
    Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme

    Therapy-resistant tumor microvascular endothelial cells contribute to treatment failure in glioblastoma multiforme 由 Tijana Borovski, Patrick Beke, Olaf van Tellingen, Hans M. Rodermond, Joost J.C. Verhoeff, Valeria Lascano, Joost Daalhuisen, Jan Paul Medema, Martin R. Sprick

    出版 2012
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  18. 18
    Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression

    Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression 由 Nienke A. de Vries, Danielle Hulsman, Waseem Akhtar, Johann de Jong, Denise C. Miles, Marleen Blom, Olaf van Tellingen, Jos Jonkers, Maarten van Lohuizen

    出版 2015
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  19. 19
    Validity of Bioluminescence Measurements for Noninvasive in Vivo Imaging of Tumor Load in Small Animals

    Validity of Bioluminescence Measurements for Noninvasive in Vivo Imaging of Tumor Load in Small Animals 由 Clara Klerk, Renée M. Overmeer, Tatjana M.H. Niers, Henri H. Versteeg, Dick J. Richel, Tessa Buckle, Cornelis J.F. Van Noorden, Olaf van Tellingen

    出版 2007
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    Revisão
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  20. 20
    Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.

    Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein. 由 Guido J.R. Zaman, J. Lankelma, Olaf van Tellingen, Jos H. Beijnen, Henk Dekker, Coen C. Paulusma, Ronald P.J. Oude Elferink, Frank Baas, Piet Borst

    出版 1995
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