Ngā hua rapu - Oehme, Ina

HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities mā Koeneke, Emily, Witt, Olaf, Oehme, Ina

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The enzyme activity of histone deacetylase 8 is modulated by a redox-switch mā Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef

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Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer mā Dovzhanskiy, Dmitriy I, Arnold, Stefanie M, Hackert, Thilo, Oehme, Ina, Witt, Olaf, Felix, Klaus, Giese, Nathalia, Werner, Jens

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MBRS-19. SYNERGISM OF HDAC AND PARP INHIBITORS IN MYC-DRIVEN GROUP 3 MEDULLOBLASTOMA CELLS mā Vollmer, Johanna, Ecker, Jonas, Hielscher, Thomas, Valinciute, Gintvile, Oppermann, Sina, Peterziel, Heike, Oehme, Ina, Witt, Olaf, Milde, Till

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The PEA-15 Protein Regulates Autophagy via Activation of JNK mā Böck, Barbara C., Tagscherer, Katrin E., Fassl, Anne, Krämer, Anika, Oehme, Ina, Zentgraf, Hans-Walter, Keith, Martina, Roth, Wilfried

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MODL-01. Targeting replication stress in pediatric brain tumors mā Krausert, Sonja, Mack, Norman, Schwalm, Benjamin, Peterziel, Heike, Oehme, Ina, van Tilburg, Cornelis M, Witt, Olaf, Pfister, Stefan M, Kool, Marcel

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Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma mā Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F., Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina

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MB-57 INTERACTION OF HDAC2 AND MYC IN GROUP 3 MEDULLOBLASTOMA - A NOVEL THERAPEUTIC TARGET mā Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Schnölzer, Martina, Warnken, Uwe, Brabetz, Sebastian, Wechsler-Reya, Robert, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Milde, Till

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Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts mā Wrobel, Jagoda K, Najafi, Sara, Ayhan, Simay, Gatzweiler, Charlotte, Krunic, Damir, Ridinger, Johannes, Milde, Till, Westermann, Frank, Peterziel, Heike, Meder, Benjamin, Distel, Martin, Witt, Olaf, Oehme, Ina

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The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines mā Kolbinger, Fiona R., Koeneke, Emily, Ridinger, Johannes, Heimburg, Tino, Müller, Michael, Bayer, Theresa, Sippl, Wolfgang, Jung, Manfred, Gunkel, Nikolas, Miller, Aubry K., Westermann, Frank, Witt, Olaf, Oehme, Ina

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Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance mā Bingel, Corinna, Koeneke, Emily, Ridinger, Johannes, Bittmann, Annika, Sill, Martin, Peterziel, Heike, Wrobel, Jagoda K, Rettig, Inga, Milde, Till, Fernekorn, Uta, Weise, Frank, Schober, Andreas, Witt, Olaf, Oehme, Ina

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Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance mā Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne, Witt, Olaf, Oehme, Ina

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Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity mā Darwish, Salma, Ghazy, Ehab, Heimburg, Tino, Herp, Daniel, Zeyen, Patrik, Salem-Altintas, Rabia, Ridinger, Johannes, Robaa, Dina, Schmidtkunz, Karin, Erdmann, Frank, Schmidt, Matthias, Romier, Christophe, Jung, Manfred, Oehme, Ina, Sippl, Wolfgang

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MEDU-20. TARGETING OF MYC BY HDAC INHIBITION IN MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA mā Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Chavez, Lukas, Hohloch, Juliane, Valinciute, Gintvile, van Tilburg, Cornelis M., Schnölzer, Martina, Warnken, Uwe, Wechsler-Reya, Robert, Pfister, Stefan M., Witt, Olaf, Milde, Till

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Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors mā Daskalakis, Michael, Brocks, David, Sheng, Yi-Hua, Islam, Md Saiful, Ressnerova, Alzbeta, Assenov, Yassen, Milde, Till, Oehme, Ina, Witt, Olaf, Goyal, Ashish, Kühn, Alexander, Hartmann, Mark, Weichenhan, Dieter, Jung, Manfred, Plass, Christoph

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Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma mā Krausert, Sonja, Brabetz, Sebastian, Mack, Norman L, Schmitt-Hoffner, Felix, Schwalm, Benjamin, Peterziel, Heike, Mangang, Aileen, Holland-Letz, Tim, Sieber, Laura, Korshunov, Andrey, Oehme, Ina, Jäger, Natalie, Witt, Olaf, Pfister, Stefan M, Kool, Marcel

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Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors mā Morgen, Michael, Steimbach, Raphael R., Géraldy, Magalie, Hellweg, Lars, Sehr, Peter, Ridinger, Johannes, Witt, Olaf, Oehme, Ina, Herbst‐Gervasoni, Corey J., Osko, Jeremy D., Porter, Nicholas J., Christianson, David W., Gunkel, Nikolas, Miller, Aubry K.

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Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma mā Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till

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Nestin Expression Identifies Ependymoma Patients with Poor Outcome mā Milde, Till, Hielscher, Thomas, Witt, Hendrik, Kool, Marcel, Mack, Stephen C., Deubzer, Hedwig E., Oehme, Ina, Lodrini, Marco, Benner, Axel, Taylor, Michael D., von Deimling, Andreas, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Korshunov, Andrey

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Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma mā Müller, Michael, Rösch, Lisa, Najafi, Sara, Gatzweiler, Charlotte, Ridinger, Johannes, Gerloff, Xenia F., Jones, David T. W., Baßler, Jochen, Kreth, Sina, Stainczyk, Sabine, Frese, Karen, Meder, Benjamin, Westermann, Frank, Milde, Till, Peterziel, Heike, Witt, Olaf, Oehme, Ina

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