Resultados da pesquisa - Oehme, Ina

HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities Por Koeneke, Emily, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

The enzyme activity of histone deacetylase 8 is modulated by a redox-switch Por Jänsch, Niklas, Meyners, Christian, Muth, Marius, Kopranovic, Aleksandra, Witt, Olaf, Oehme, Ina, Meyer-Almes, Franz-Josef

Obter o texto integral Obter o texto integral Obter o texto integral

Experimental in vivo and in vitro treatment with a new histone deacetylase inhibitor belinostat inhibits the growth of pancreatic cancer Por Dovzhanskiy, Dmitriy I, Arnold, Stefanie M, Hackert, Thilo, Oehme, Ina, Witt, Olaf, Felix, Klaus, Giese, Nathalia, Werner, Jens

Obter o texto integral Obter o texto integral Obter o texto integral

MBRS-19. SYNERGISM OF HDAC AND PARP INHIBITORS IN MYC-DRIVEN GROUP 3 MEDULLOBLASTOMA CELLS Por Vollmer, Johanna, Ecker, Jonas, Hielscher, Thomas, Valinciute, Gintvile, Oppermann, Sina, Peterziel, Heike, Oehme, Ina, Witt, Olaf, Milde, Till

Obter o texto integral Obter o texto integral

The PEA-15 Protein Regulates Autophagy via Activation of JNK Por Böck, Barbara C., Tagscherer, Katrin E., Fassl, Anne, Krämer, Anika, Oehme, Ina, Zentgraf, Hans-Walter, Keith, Martina, Roth, Wilfried

Obter o texto integral Obter o texto integral Obter o texto integral

MODL-01. Targeting replication stress in pediatric brain tumors Por Krausert, Sonja, Mack, Norman, Schwalm, Benjamin, Peterziel, Heike, Oehme, Ina, van Tilburg, Cornelis M, Witt, Olaf, Pfister, Stefan M, Kool, Marcel

Obter o texto integral Obter o texto integral

Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma Por Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F., Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

MB-57 INTERACTION OF HDAC2 AND MYC IN GROUP 3 MEDULLOBLASTOMA - A NOVEL THERAPEUTIC TARGET Por Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Schnölzer, Martina, Warnken, Uwe, Brabetz, Sebastian, Wechsler-Reya, Robert, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Milde, Till

Obter o texto integral Obter o texto integral

Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts Por Wrobel, Jagoda K, Najafi, Sara, Ayhan, Simay, Gatzweiler, Charlotte, Krunic, Damir, Ridinger, Johannes, Milde, Till, Westermann, Frank, Peterziel, Heike, Meder, Benjamin, Distel, Martin, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines Por Kolbinger, Fiona R., Koeneke, Emily, Ridinger, Johannes, Heimburg, Tino, Müller, Michael, Bayer, Theresa, Sippl, Wolfgang, Jung, Manfred, Gunkel, Nikolas, Miller, Aubry K., Westermann, Frank, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance Por Bingel, Corinna, Koeneke, Emily, Ridinger, Johannes, Bittmann, Annika, Sill, Martin, Peterziel, Heike, Wrobel, Jagoda K, Rettig, Inga, Milde, Till, Fernekorn, Uta, Weise, Frank, Schober, Andreas, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance Por Ridinger, Johannes, Koeneke, Emily, Kolbinger, Fiona R., Koerholz, Katharina, Mahboobi, Siavosh, Hellweg, Lars, Gunkel, Nikolas, Miller, Aubry K., Peterziel, Heike, Schmezer, Peter, Hamacher-Brady, Anne, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral

Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity Por Darwish, Salma, Ghazy, Ehab, Heimburg, Tino, Herp, Daniel, Zeyen, Patrik, Salem-Altintas, Rabia, Ridinger, Johannes, Robaa, Dina, Schmidtkunz, Karin, Erdmann, Frank, Schmidt, Matthias, Romier, Christophe, Jung, Manfred, Oehme, Ina, Sippl, Wolfgang

Obter o texto integral Obter o texto integral Obter o texto integral

MEDU-20. TARGETING OF MYC BY HDAC INHIBITION IN MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA Por Ecker, Jonas, Oehme, Ina, Selt, Florian, Kool, Marcel, Chavez, Lukas, Hohloch, Juliane, Valinciute, Gintvile, van Tilburg, Cornelis M., Schnölzer, Martina, Warnken, Uwe, Wechsler-Reya, Robert, Pfister, Stefan M., Witt, Olaf, Milde, Till

Obter o texto integral Obter o texto integral

Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors Por Daskalakis, Michael, Brocks, David, Sheng, Yi-Hua, Islam, Md Saiful, Ressnerova, Alzbeta, Assenov, Yassen, Milde, Till, Oehme, Ina, Witt, Olaf, Goyal, Ashish, Kühn, Alexander, Hartmann, Mark, Weichenhan, Dieter, Jung, Manfred, Plass, Christoph

Obter o texto integral Obter o texto integral Obter o texto integral

Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma Por Krausert, Sonja, Brabetz, Sebastian, Mack, Norman L, Schmitt-Hoffner, Felix, Schwalm, Benjamin, Peterziel, Heike, Mangang, Aileen, Holland-Letz, Tim, Sieber, Laura, Korshunov, Andrey, Oehme, Ina, Jäger, Natalie, Witt, Olaf, Pfister, Stefan M, Kool, Marcel

Obter o texto integral Obter o texto integral Obter o texto integral

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors Por Morgen, Michael, Steimbach, Raphael R., Géraldy, Magalie, Hellweg, Lars, Sehr, Peter, Ridinger, Johannes, Witt, Olaf, Oehme, Ina, Herbst‐Gervasoni, Corey J., Osko, Jeremy D., Porter, Nicholas J., Christianson, David W., Gunkel, Nikolas, Miller, Aubry K.

Obter o texto integral Obter o texto integral Obter o texto integral

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma Por Ecker, Jonas, Oehme, Ina, Mazitschek, Ralph, Korshunov, Andrey, Kool, Marcel, Hielscher, Thomas, Kiss, Judit, Selt, Florian, Konrad, Carina, Lodrini, Marco, Deubzer, Hedwig E, von Deimling, Andreas, Kulozik, Andreas E, Pfister, Stefan M, Witt, Olaf, Milde, Till

Obter o texto integral Obter o texto integral Obter o texto integral

Nestin Expression Identifies Ependymoma Patients with Poor Outcome Por Milde, Till, Hielscher, Thomas, Witt, Hendrik, Kool, Marcel, Mack, Stephen C., Deubzer, Hedwig E., Oehme, Ina, Lodrini, Marco, Benner, Axel, Taylor, Michael D., von Deimling, Andreas, Kulozik, Andreas E., Pfister, Stefan M., Witt, Olaf, Korshunov, Andrey

Obter o texto integral Obter o texto integral Obter o texto integral

Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma Por Müller, Michael, Rösch, Lisa, Najafi, Sara, Gatzweiler, Charlotte, Ridinger, Johannes, Gerloff, Xenia F., Jones, David T. W., Baßler, Jochen, Kreth, Sina, Stainczyk, Sabine, Frese, Karen, Meder, Benjamin, Westermann, Frank, Milde, Till, Peterziel, Heike, Witt, Olaf, Oehme, Ina

Obter o texto integral Obter o texto integral Obter o texto integral