Výsledky vyhledávání - Nobuya Ishii

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  1. 1
    Role of hydrosulfide ions (HS-) in methylmercury resistance in Saccharomyces cerevisiae

    Role of hydrosulfide ions (HS-) in methylmercury resistance in Saccharomyces cerevisiae Autor Bun‐ichiro Ono, Nobuya Ishii, Shota Fujino, Isao Aoyama

    Vydáno 1991
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    Artigo
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  2. 2
    Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3–BAIAP2L1

    Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3–BAIAP2L1 Autor Yoshito Nakanishi, Nukinori Akiyama, Toshiyuki Tsukaguchi, Toshihiko Fujii, Yasuko Satoh, Nobuya Ishii, Masahiro Aoki

    Vydáno 2015
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  3. 3
    CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant

    CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant Autor Hiroshi Sakamoto, Toshiyuki Tsukaguchi, Sayuri Hiroshima, Tatsushi Kodama, Takamitsu Kobayashi, Takaaki A. Fukami, Nobuhiro Oikawa, Takuo Tsukuda, Nobuya Ishii, Yuko Aoki

    Vydáno 2011
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  4. 4
    The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH5183284/Debio 1347, a Novel Selective FGFR Inhibitor

    The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH5183284/Debio 1347, a Novel Selective FGFR Inhibitor Autor Yoshito Nakanishi, Nukinori Akiyama, Toshiyuki Tsukaguchi, Toshihiko Fujii, Kiyoaki Sakata, Hitoshi Sase, Takehito Isobe, Kenji Morikami, Hidetoshi Shindoh, Toshiyuki Mio, Hirosato Ebiike, Naoki Taka, Yuko Aoki, Nobuya Ishii

    Vydáno 2014
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  5. 5
    The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic <i>PIK3CA</i> Mutations

    The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic <i>PIK3CA</i> Mutations Autor Hiroshi Tanaka, Miyuki Yoshida, Hiromi Tanimura, Toshihiko Fujii, Kiyoaki Sakata, Yukako Tachibana, Jun Ohwada, Hirosato Ebiike, Shino Kuramoto, Keiichi Morita, Yasushi Yoshimura, Toshikazu Yamazaki, Nobuya Ishii, Osamu Kondoh, Yuko Aoki

    Vydáno 2011
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  6. 6
    Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors

    Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors Autor Piro Lito, Anna Saborowski, Jingyin Yue, Martha Solomon, Eric W. Joseph, Sunyana Gadal, Michael Saborowski, Edward R. Kastenhuber, Christof Fellmann, Kazuhiro Ohara, Kenji Morikami, Takaaki Miura, Christine Lukacs, Nobuya Ishii, Scott W. Lowe, Neal Rosen

    Vydáno 2014
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  7. 7
    YES1 Is a Targetable Oncogene in Cancers Harboring <i>YES1</i> Gene Amplification

    YES1 Is a Targetable Oncogene in Cancers Harboring <i>YES1</i> Gene Amplification Autor Natsuki Hamanaka, Yoshito Nakanishi, Takakazu Mizuno, Kana Horiguchi-Takei, Nukinori Akiyama, Hiromi Tanimura, Masami Hasegawa, Yasuko Satoh, Yukako Tachibana, Toshihiko Fujii, Kiyoaki Sakata, Kiyomoto Ogasawara, Hirosato Ebiike, Hiroshi Koyano, Haruhiko Sato, Nobuya Ishii, Toshiyuki Mio

    Vydáno 2019
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  8. 8
    Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity

    Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity Autor Nobuya Ishii, Naoki Harada, Eric W. Joseph, Kazuhiro Ohara, Takaaki Miura, Hiroshi Sakamoto, Yutaka Matsuda, Yasushi Tomii, Yukako Tachibana-Kondo, Hitoshi Iikura, Toshihiro Aoki, Nobuo Shimma, Mikio Arisawa, Yoshihiro Sowa, Poulikos I. Poulikakos, Neal Rosen, Yuko Aoki, Toshiyuki Sakai

    Vydáno 2013
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  9. 9
    Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine

    Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine Autor James Nagarajah, Mina Le, Jeffrey A. Knauf, Giuseppe Ferrandino, Cristina Montero‐Conde, Nagavarakishore Pillarsetty, Alexander Bolaender, Christopher Irwin, Gnana P. Krishnamoorthy, Mahesh Saqcena, Steven M. Larson, Alan L. Ho, Venkatraman Seshan, Nobuya Ishii, Nancy Carrasco, Neal Rosen, Wolfgang Weber, James A. Fagin

    Vydáno 2016
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  10. 10
    A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring <i>FGFR</i> Gene Alterations

    A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring <i>FGFR</i> Gene Alterati... Autor Martin H. Voss, Cinta Hierro, Rebecca S. Heist, James M. Cleary, Funda Meric‐Bernstam, Josep Tabernero, Filip Janků, Leena Gandhi, A. John Iafrate, Darrell R. Borger, Nobuya Ishii, Youyou Hu, Yulia Kirpicheva, Valerie Nicolas‐Métral, Anna Pokorska-Bocci, Anne Vaslin Chessex, Claudio Zanna, Keith T. Flaherty, José Baselga

    Vydáno 2019
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