Risultati della ricerca - Nitsch, Roberto

TNF-driven cell fate: till HACE do us part di Tortola, Luigi, Nitsch, Roberto, Penninger, Josef M.

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WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8. di Nitsch, Roberto, Di Palma, Tina, Mascia, Anna, Zannini, Mariastella

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Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq di Dobbs, Felix M., van Eijk, Patrick, Fellows, Mick D., Loiacono, Luisa, Nitsch, Roberto, Reed, Simon H.

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Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene di Nitsch, Roberto, Di Dato, Valeria, di Gennaro, Alessandra, de Cristofaro, Tiziana, Abbondante, Serena, De Felice, Mario, Zannini, Mariastella, Di Lauro, Roberto

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Pendrin Is a Novel In Vivo Downstream Target Gene of the TTF-1/Nkx-2.1 Homeodomain Transcription Factor in Differentiated Thyroid Cells di Dentice, Monica, Luongo, Cristina, Elefante, Antonia, Ambrosio, Raffaele, Salzano, Salvatore, Zannini, Mariastella, Nitsch, Roberto, Di Lauro, Roberto, Rossi, Guido, Fenzi, Gianfranco, Salvatore, Domenico

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Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype di Bjursell, Mikael, Porritt, Michelle J., Ericson, Elke, Taheri-Ghahfarokhi, Amir, Clausen, Maryam, Magnusson, Lisa, Admyre, Therese, Nitsch, Roberto, Mayr, Lorenz, Aasehaug, Leif, Seeliger, Frank, Maresca, Marcello, Bohlooly-Y, Mohammad, Wiseman, John

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Decoding non-random mutational signatures at Cas9 targeted sites di Taheri-Ghahfarokhi, Amir, Taylor, Benjamin J M, Nitsch, Roberto, Lundin, Anders, Cavallo, Anna-Lina, Madeyski-Bengtson, Katja, Karlsson, Fredrik, Clausen, Maryam, Hicks, Ryan, Mayr, Lorenz M, Bohlooly-Y, Mohammad, Maresca, Marcello

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Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes di Daugaard, Mads, Nitsch, Roberto, Razaghi, Babak, McDonald, Lindsay, Jarrar, Ameer, Torrino, Stéphanie, Castillo-Lluva, Sonia, Rotblat, Barak, Li, Liheng, Malliri, Angeliki, Lemichez, Emmanuel, Mettouchi, Amel, Berman, Jason N., Penninger, Josef M., Sorensen, Poul H.

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In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model di Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M., Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello

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The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells di Paolino, Magdalena, Choidas, Axel, Wallner, Stephanie, Pranjic, Blanka, Uribesalgo, Iris, Loeser, Stefanie, Jamieson, Amanda M., Langdon, Wallace Y., Ikeda, Fumiyo, Fededa, Juan P., Cronin, Shane J., Nitsch, Roberto, Schultz-Fademrecht, Carsten, Eickhoff, Jan, Menninger, Sascha, Unger, Anke, Torka, Robert, Gruber, Thomas, Hinterleitner, Reinhard, Baier, Gottfried, Wolf, Dominik, Ullrich, Axel, Klebl, Bert M., Penninger, Josef M.

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Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery di Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello

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In vivo CRISPR editing with no detectable genome-wide off-target mutations di Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith

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HACE1 deficiency leads to structural and functional neurodevelopmental defects di Nagy, Vanja, Hollstein, Ronja, Pai, Tsung-Pin, Herde, Michel K., Buphamalai, Pisanu, Moeseneder, Paul, Lenartowicz, Ewelina, Kavirayani, Anoop, Korenke, Georg Christoph, Kozieradzki, Ivona, Nitsch, Roberto, Cicvaric, Ana, Monje Quiroga, Francisco J., Deardorff, Matthew A., Bedoukian, Emma C., Li, Yun, Yigit, Gökhan, Menche, Jörg, Perçin, E. Ferda, Wollnik, Bernd, Henneberger, Christian, Kaiser, Frank J., Penninger, Josef M.

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HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases di Kogler, Melanie, Tortola, Luigi, Negri, Gian Luca, Leopoldi, Alexandra, El-Naggar, Amal M., Mereiter, Stefan, Diaz, Carlos Gomez, Nitsch, Roberto, Tortora, Davide, Kavirayani, Anoop M., Gapp, Bianca V., Rao, Shuan, Uribesalgo, Iris, Hoffmann, David, Cikes, Domagoj, Novatchkova, Maria, Williams, David A., Trent, Jeffrey M., Ikeda, Fumiyo, Daugaard, Mads, Hagelkruys, Astrid, Sorensen, Poul H., Penninger, Josef M.

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HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response di Rotblat, Barak, Southwell, Amber L., Ehrnhoefer, Dagmar E., Skotte, Niels H., Metzler, Martina, Franciosi, Sonia, Leprivier, Gabriel, Somasekharan, Syam Prakash, Barokas, Adi, Deng, Yu, Tang, Tiffany, Mathers, Joan, Cetinbas, Naniye, Daugaard, Mads, Kwok, Brian, Li, Liheng, Carnie, Christopher J., Fink, Dieter, Nitsch, Roberto, Galpin, Jason D., Ahern, Christopher A., Melino, Gerry, Penninger, Josef M., Hayden, Michael R., Sorensen, Poul H.

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The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate di Tortola, Luigi, Nitsch, Roberto, Bertrand, Mathieu J.M., Kogler, Melanie, Redouane, Younes, Kozieradzki, Ivona, Uribesalgo, Iris, Fennell, Lilian M., Daugaard, Mads, Klug, Helene, Wirnsberger, Gerald, Wimmer, Reiner, Perlot, Thomas, Sarao, Renu, Rao, Shuan, Hanada, Toshikatsu, Takahashi, Nozomi, Kernbauer, Elisabeth, Demiröz, Duygu, Superti-Furga, Giulio, Decker, Thomas, Pichler, Andrea, Ikeda, Fumiyo, Kroemer, Guido, Vandenabeele, Peter, Sorensen, Poul H., Penninger, Josef M.

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The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate di Tortola, Luigi, Nitsch, Roberto, Bertrand, Mathieu J.M., Kogler, Melanie, Redouane, Younes, Kozieradzki, Ivona, Uribesalgo, Iris, Fennell, Lilian M., Daugaard, Mads, Klug, Helene, Wirnsberger, Gerald, Wimmer, Reiner, Perlot, Thomas, Sarao, Renu, Rao, Shuan, Hanada, Toshikatsu, Takahashi, Nozomi, Kernbauer, Elisabeth, Demiröz, Duygu, Lang, Michaela, Superti-Furga, Giulio, Decker, Thomas, Pichler, Andrea, Ikeda, Fumiyo, Kroemer, Guido, Vandenabeele, Peter, Sorensen, Poul H., Penninger, Josef M.

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RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer di Rao, Shuan, Sigl, Verena, Wimmer, Reiner Alois, Novatchkova, Maria, Jais, Alexander, Wagner, Gabriel, Handschuh, Stephan, Uribesalgo, Iris, Hagelkruys, Astrid, Kozieradzki, Ivona, Tortola, Luigi, Nitsch, Roberto, Cronin, Shane J., Orthofer, Michael, Branstetter, Daniel, Canon, Jude, Rossi, John, D'Arcangelo, Manolo, Botling, Johan, Micke, Patrick, Fleur, Linnea La, Edlund, Karolina, Bergqvist, Michael, Ekman, Simon, Lendl, Thomas, Popper, Helmut, Takayanagi, Hiroshi, Kenner, Lukas, Hirsch, Fred R., Dougall, William, Penninger, Josef M.

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