Canlyniadau Chwilio - Nitsch, Roberto

TNF-driven cell fate: till HACE do us part gan Tortola, Luigi, Nitsch, Roberto, Penninger, Josef M.

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WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8. gan Nitsch, Roberto, Di Palma, Tina, Mascia, Anna, Zannini, Mariastella

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Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq gan Dobbs, Felix M., van Eijk, Patrick, Fellows, Mick D., Loiacono, Luisa, Nitsch, Roberto, Reed, Simon H.

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Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene gan Nitsch, Roberto, Di Dato, Valeria, di Gennaro, Alessandra, de Cristofaro, Tiziana, Abbondante, Serena, De Felice, Mario, Zannini, Mariastella, Di Lauro, Roberto

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Pendrin Is a Novel In Vivo Downstream Target Gene of the TTF-1/Nkx-2.1 Homeodomain Transcription Factor in Differentiated Thyroid Cells gan Dentice, Monica, Luongo, Cristina, Elefante, Antonia, Ambrosio, Raffaele, Salzano, Salvatore, Zannini, Mariastella, Nitsch, Roberto, Di Lauro, Roberto, Rossi, Guido, Fenzi, Gianfranco, Salvatore, Domenico

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Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype gan Bjursell, Mikael, Porritt, Michelle J., Ericson, Elke, Taheri-Ghahfarokhi, Amir, Clausen, Maryam, Magnusson, Lisa, Admyre, Therese, Nitsch, Roberto, Mayr, Lorenz, Aasehaug, Leif, Seeliger, Frank, Maresca, Marcello, Bohlooly-Y, Mohammad, Wiseman, John

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Decoding non-random mutational signatures at Cas9 targeted sites gan Taheri-Ghahfarokhi, Amir, Taylor, Benjamin J M, Nitsch, Roberto, Lundin, Anders, Cavallo, Anna-Lina, Madeyski-Bengtson, Katja, Karlsson, Fredrik, Clausen, Maryam, Hicks, Ryan, Mayr, Lorenz M, Bohlooly-Y, Mohammad, Maresca, Marcello

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Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes gan Daugaard, Mads, Nitsch, Roberto, Razaghi, Babak, McDonald, Lindsay, Jarrar, Ameer, Torrino, Stéphanie, Castillo-Lluva, Sonia, Rotblat, Barak, Li, Liheng, Malliri, Angeliki, Lemichez, Emmanuel, Mettouchi, Amel, Berman, Jason N., Penninger, Josef M., Sorensen, Poul H.

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In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model gan Carreras, Alba, Pane, Luna Simona, Nitsch, Roberto, Madeyski-Bengtson, Katja, Porritt, Michelle, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Ericson, Elke, Bjursell, Mikael, Perez-Alcazar, Marta, Seeliger, Frank, Althage, Magnus, Knöll, Ralph, Hicks, Ryan, Mayr, Lorenz M., Perkins, Rosie, Lindén, Daniel, Borén, Jan, Bohlooly-Y, Mohammad, Maresca, Marcello

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The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells gan Paolino, Magdalena, Choidas, Axel, Wallner, Stephanie, Pranjic, Blanka, Uribesalgo, Iris, Loeser, Stefanie, Jamieson, Amanda M., Langdon, Wallace Y., Ikeda, Fumiyo, Fededa, Juan P., Cronin, Shane J., Nitsch, Roberto, Schultz-Fademrecht, Carsten, Eickhoff, Jan, Menninger, Sascha, Unger, Anke, Torka, Robert, Gruber, Thomas, Hinterleitner, Reinhard, Baier, Gottfried, Wolf, Dominik, Ullrich, Axel, Klebl, Bert M., Penninger, Josef M.

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Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery gan Lundin, Anders, Porritt, Michelle J., Jaiswal, Himjyot, Seeliger, Frank, Johansson, Camilla, Bidar, Abdel Wahad, Badertscher, Lukas, Wimberger, Sandra, Davies, Emma J., Hardaker, Elizabeth, Martins, Carla P., James, Emily, Admyre, Therese, Taheri-Ghahfarokhi, Amir, Bradley, Jenna, Schantz, Anna, Alaeimahabadi, Babak, Clausen, Maryam, Xu, Xiufeng, Mayr, Lorenz M., Nitsch, Roberto, Bohlooly-Y, Mohammad, Barry, Simon T., Maresca, Marcello

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In vivo CRISPR editing with no detectable genome-wide off-target mutations gan Akcakaya, Pinar, Bobbin, Maggie L., Guo, Jimmy A., Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P., Fellows, Mick D., Porritt, Michelle J., Firth, Mike A., Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q., Nguyen, Nhu T., Nitsch, Roberto, Mayr, Lorenz M., Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J., Maresca, Marcello, Joung, J. Keith

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HACE1 deficiency leads to structural and functional neurodevelopmental defects gan Nagy, Vanja, Hollstein, Ronja, Pai, Tsung-Pin, Herde, Michel K., Buphamalai, Pisanu, Moeseneder, Paul, Lenartowicz, Ewelina, Kavirayani, Anoop, Korenke, Georg Christoph, Kozieradzki, Ivona, Nitsch, Roberto, Cicvaric, Ana, Monje Quiroga, Francisco J., Deardorff, Matthew A., Bedoukian, Emma C., Li, Yun, Yigit, Gökhan, Menche, Jörg, Perçin, E. Ferda, Wollnik, Bernd, Henneberger, Christian, Kaiser, Frank J., Penninger, Josef M.

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HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases gan Kogler, Melanie, Tortola, Luigi, Negri, Gian Luca, Leopoldi, Alexandra, El-Naggar, Amal M., Mereiter, Stefan, Diaz, Carlos Gomez, Nitsch, Roberto, Tortora, Davide, Kavirayani, Anoop M., Gapp, Bianca V., Rao, Shuan, Uribesalgo, Iris, Hoffmann, David, Cikes, Domagoj, Novatchkova, Maria, Williams, David A., Trent, Jeffrey M., Ikeda, Fumiyo, Daugaard, Mads, Hagelkruys, Astrid, Sorensen, Poul H., Penninger, Josef M.

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HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response gan Rotblat, Barak, Southwell, Amber L., Ehrnhoefer, Dagmar E., Skotte, Niels H., Metzler, Martina, Franciosi, Sonia, Leprivier, Gabriel, Somasekharan, Syam Prakash, Barokas, Adi, Deng, Yu, Tang, Tiffany, Mathers, Joan, Cetinbas, Naniye, Daugaard, Mads, Kwok, Brian, Li, Liheng, Carnie, Christopher J., Fink, Dieter, Nitsch, Roberto, Galpin, Jason D., Ahern, Christopher A., Melino, Gerry, Penninger, Josef M., Hayden, Michael R., Sorensen, Poul H.

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The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate gan Tortola, Luigi, Nitsch, Roberto, Bertrand, Mathieu J.M., Kogler, Melanie, Redouane, Younes, Kozieradzki, Ivona, Uribesalgo, Iris, Fennell, Lilian M., Daugaard, Mads, Klug, Helene, Wirnsberger, Gerald, Wimmer, Reiner, Perlot, Thomas, Sarao, Renu, Rao, Shuan, Hanada, Toshikatsu, Takahashi, Nozomi, Kernbauer, Elisabeth, Demiröz, Duygu, Superti-Furga, Giulio, Decker, Thomas, Pichler, Andrea, Ikeda, Fumiyo, Kroemer, Guido, Vandenabeele, Peter, Sorensen, Poul H., Penninger, Josef M.

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The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate gan Tortola, Luigi, Nitsch, Roberto, Bertrand, Mathieu J.M., Kogler, Melanie, Redouane, Younes, Kozieradzki, Ivona, Uribesalgo, Iris, Fennell, Lilian M., Daugaard, Mads, Klug, Helene, Wirnsberger, Gerald, Wimmer, Reiner, Perlot, Thomas, Sarao, Renu, Rao, Shuan, Hanada, Toshikatsu, Takahashi, Nozomi, Kernbauer, Elisabeth, Demiröz, Duygu, Lang, Michaela, Superti-Furga, Giulio, Decker, Thomas, Pichler, Andrea, Ikeda, Fumiyo, Kroemer, Guido, Vandenabeele, Peter, Sorensen, Poul H., Penninger, Josef M.

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RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer gan Rao, Shuan, Sigl, Verena, Wimmer, Reiner Alois, Novatchkova, Maria, Jais, Alexander, Wagner, Gabriel, Handschuh, Stephan, Uribesalgo, Iris, Hagelkruys, Astrid, Kozieradzki, Ivona, Tortola, Luigi, Nitsch, Roberto, Cronin, Shane J., Orthofer, Michael, Branstetter, Daniel, Canon, Jude, Rossi, John, D'Arcangelo, Manolo, Botling, Johan, Micke, Patrick, Fleur, Linnea La, Edlund, Karolina, Bergqvist, Michael, Ekman, Simon, Lendl, Thomas, Popper, Helmut, Takayanagi, Hiroshi, Kenner, Lukas, Hirsch, Fred R., Dougall, William, Penninger, Josef M.

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