檢索結果 - Nikolaos G. Sgourakis

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  1. 1
    A slow-exchange conformational switch regulates off-target cleavage by high-fidelity Cas9

    A slow-exchange conformational switch regulates off-target cleavage by high-fidelity Cas9 由 Viviane S. De Paula, Abhinav Dubey, Haribabu Arthanari, Nikolaos G. Sgourakis

    出版 2020
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  2. 2
    Backbone-independent NMR resonance assignments of methyl probes in large proteins

    Backbone-independent NMR resonance assignments of methyl probes in large proteins 由 Santrupti Nerli, Viviane S. De Paula, Andrew C. McShan, Nikolaos G. Sgourakis

    出版 2021
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  3. 3
    HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes

    HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes 由 Sagar Gupta, Santrupti Nerli, Sreeja Kutti Kandy, Glenn L. Mersky, Nikolaos G. Sgourakis

    出版 2023
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  4. 4
    The Alzheimer’s Peptides Aβ40 and 42 Adopt Distinct Conformations in Water: A Combined MD / NMR Study

    The Alzheimer’s Peptides Aβ40 and 42 Adopt Distinct Conformations in Water: A Combined MD / NMR Study 由 Nikolaos G. Sgourakis, Yilin Yan, Scott A. McCallum, Chunyu Wang, Angel E. Garcı́a

    出版 2007
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  5. 5
    NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition

    NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition 由 Viviane S. De Paula, Nikolaos G. Sgourakis, Ivo M.B. Francischetti, Fábio C. L. Almeida, Robson Q. Monteiro, Ana Paula Valente

    出版 2019
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  6. 6
    Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings

    Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings 由 Nikolaos G. Sgourakis, Oliver F. Lange, Frank DiMaio, Ingemar André, Nicholas C. Fitzkee, P. Rossi, G.T. Montelione, Ad Bax, David Baker

    出版 2011
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  7. 7
    TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap

    TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap 由 Andrew C. McShan, Christine A. Devlin, Giora I. Morozov, Sarah A. Overall, Danai Moschidi, Neha M. Akella, Erik Procko, Nikolaos G. Sgourakis

    出版 2021
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  8. 8
    The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles

    The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles 由 Jean‐Philippe Demers, Nikolaos G. Sgourakis, Rashmi Gupta, Antoine Loquet, Karin Giller, Dietmar Riedel, Britta Laube, Michael Kolbe, David Baker, Stefan Becker, Adam Lange

    出版 2013
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  9. 9
    Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes

    Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes 由 Yi Sun, Georgia Papadaki, Christine A. Devlin, Julia N. Danon, Michael C. Young, Trenton J. Winters, George M. Burslem, Erik Procko, Nikolaos G. Sgourakis

    出版 2023
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  10. 10
    The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

    The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling 由 Kannan Natarajan, Jiansheng Jiang, Nathan A. May, Michael G. Mage, Lisa F. Boyd, Andrew C. McShan, Nikolaos G. Sgourakis, Ad Bax, David H. Margulies

    出版 2018
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  11. 11
    Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples

    Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples 由 Oliver F. Lange, P. Rossi, Nikolaos G. Sgourakis, Yifan Song, Hsiau‐Wei Lee, James M. Aramini, Asli Ertekin, Rong Xiao, Thomas Acton, G.T. Montelione, David Baker

    出版 2012
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  12. 12
    CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading

    CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading 由 Yi Sun, Ruth A. Pumroy, Leena Mallik, Apala Chaudhuri, Xiaoming Wang, Daniel Hwang, Julia N. Danon, Kimia Dasteh Goli, Vera Y. Moiseenkova‐Bell, Nikolaos G. Sgourakis

    出版 2025
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  13. 13
    Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

    Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection 由 Andrew C. McShan, Christine A. Devlin, Sarah A. Overall, Jihye Park, Jugmohit Toor, Danai Moschidi, David Flores‐Solis, Hannah Choi, Sarvind Tripathi, Erik Procko, Nikolaos G. Sgourakis

    出版 2019
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  14. 14
    Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes

    Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes 由 Yi Sun, Michael C. Young, Claire H. Woodward, Julia N. Danon, Hau V. Truong, Sagar Gupta, Trenton J. Winters, Joan Font-Burgada, George M. Burslem, Nikolaos G. Sgourakis

    出版 2023
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  15. 15
    An order-to-disorder structural switch activates the FoxM1 transcription factor

    An order-to-disorder structural switch activates the FoxM1 transcription factor 由 Aimee H. Marceau, Caileen M. Brison, Santrupti Nerli, Heather E. Arsenault, Andrew C. McShan, Eefei Chen, Hsiau‐Wei Lee, Jennifer A. Benanti, Nikolaos G. Sgourakis, Seth M. Rubin

    出版 2019
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  16. 16
    Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

    Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle 由 Andrew C. McShan, Kannan Natarajan, Vlad K. Kumirov, David Flores‐Solis, Jiansheng Jiang, Mareike Badstübner, Jugmohit Toor, Clive R. Bagshaw, Evgenii L. Kovrigin, David H. Margulies, Nikolaos G. Sgourakis

    出版 2018
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  17. 17
    De novo design of a non-local β-sheet protein with high stability and accuracy

    De novo design of a non-local β-sheet protein with high stability and accuracy 由 Enrique Marcos, Tamuka M. Chidyausiku, Andrew C. McShan, Thomas Evangelidis, Santrupti Nerli, Lauren Carter, Lucas G. Nivón, Audrey L. Davis, Gustav Oberdorfer, Konstantinos Tripsianes, Nikolaos G. Sgourakis, David Baker

    出版 2018
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  18. 18
    The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body

    The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body 由 Julien R. C. Bergeron, L.J. Worrall, Soumya De, Nikolaos G. Sgourakis, Adrienne H. Cheung, Emilie Lameignère, Mark Okon, Gregory A. Wasney, David Baker, Lawrence P. McIntosh, N.C.J. Strynadka

    出版 2014
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  19. 19
    Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation

    Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation 由 Jiansheng Jiang, Daniel K. Taylor, Ellen J. Kim, Lisa F. Boyd, Javeed Ahmad, Michael G. Mage, Hau V. Truong, Claire H. Woodward, Nikolaos G. Sgourakis, Peter Cresswell, David H. Margulies, Kannan Natarajan

    出版 2022
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  20. 20
    An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role

    An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role 由 Kannan Natarajan, Andrew C. McShan, Jiansheng Jiang, Vlad K. Kumirov, Rui Wang, Huaying Zhao, Peter Schuck, Mulualem E. Tilahun, Lisa F. Boyd, Jinfa Ying, Ad Bax, David H. Margulies, Nikolaos G. Sgourakis

    出版 2017
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