Rezultati - Nigel W. Rayner

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  1. 1
    Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits

    Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits od Lorraine Southam, Arthur Gilly, Dániel Süveges, Aliki‐Eleni Farmaki, Jeremy Schwartzentruber, Ioanna Tachmazidou, Angela Matchan, Nigel W. Rayner, Emmanouil Tsafantakis, Maria Karaleftheri, Yali Xue, George Dedoussis, Eleftheria Zeggini

    Izdano 2017
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  2. 2
    Whole-genome sequencing analysis of the cardiometabolic proteome

    Whole-genome sequencing analysis of the cardiometabolic proteome od Arthur Gilly, Young‐Chan Park, Grace Png, Andrei Barysenka, Iris Fischer, Thea Bjørnland, Lorraine Southam, Dániel Süveges, Sonja Neumeyer, Nigel W. Rayner, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Eleftheria Zeggini

    Izdano 2020
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  3. 3
    Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction

    Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction od Michael N. Weedon, Mark I. McCarthy, G. A. Hitman, Mark Walker, Christopher J. Groves, Eleftheria Zeggini, Nigel W. Rayner, Beverley M. Shields, Katharine R. Owen, Andrew T. Hattersley, Timothy M. Frayling

    Izdano 2006
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  4. 4
    Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms <i>TCF7L2</i> as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

    Association Analysis of 6,736 U.K. Subjects Provides Replication and Confirms <i>TCF7L2</i> as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk od Christopher J. Groves, Eleftheria Zeggini, Jayne A.L. Minton, Timothy M. Frayling, Michael N. Weedon, Nigel W. Rayner, G. A. Hitman, Mark Walker, Steven Wiltshire, Andrew T. Hattersley, Mark I. McCarthy

    Izdano 2006
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  5. 5
    Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity

    Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity od Elena Kempf, Kathrin Landgraf, Robert Stein, Martha Hanschkow, Anja Hilbert, Rami Abou Jamra, Paula Boczki, Gunda Herberth, Andreas Kühnapfel, Yu‐Hua Tseng, Claudia Stäubert, Torsten Schöneberg, Peter Kühnen, Nigel W. Rayner, Eleftheria Zeggini, Wieland Kieß, Matthias Blüher, Antje Körner

    Izdano 2022
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  6. 6
    MicroRNA Expression in Abdominal and Gluteal Adipose Tissue Is Associated with mRNA Expression Levels and Partly Genetically Driven

    MicroRNA Expression in Abdominal and Gluteal Adipose Tissue Is Associated with mRNA Expression Levels and Partly Genetically Driven od Mattias Rantalainen, Blanca Herrera, Geoffrey C. Nicholson, Rory Bowden, Quin F. Wills, Josine L. Min, Matt J. Neville, Amy Barrett, Maxine Allen, Nigel W. Rayner, Jan Fleckner, Mark I. McCarthy, Krina T. Zondervan, Fredrik Karpe, Chris Holmes, Cecilia M. Lindgren

    Izdano 2011
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  7. 7
    Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

    Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany od Anke Tönjes, Eleftheria Zeggini, Péter Kovács, Yvonne Böttcher, Dorit Schleinitz, Kerstin Dietrich, Andrew P. Morris, Beate Enigk, Nigel W. Rayner, Moritz Koriath, Markus Eszlinger, Anu Kemppinen, Inga Prokopenko, Katrin Hoffmann, Daniel Teupser, Joachim Thiery, Knut Krohn, Mark I. McCarthy, Michael Stümvoll

    Izdano 2009
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  8. 8
    Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

    Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs od Anke Tönjes, Moritz Koriath, Dorit Schleinitz, Kerstin Dietrich, Yvonne Böttcher, Nigel W. Rayner, Peter Almgren, Beate Enigk, Olaf Richter, Silvio Rohm, Antje Fischer-Rosinský, A. Pfeiffer, Katrin Hoffmann, Knut Krohn, Gabriela Aust, Joachim Spranger, Leif Groop, Matthias Blüher, Péter Kovács, Michael Stümvoll

    Izdano 2009
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  9. 9
    Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

    Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data od Nicholas J. Timpson, Cecilia M. Lindgren, Michael N. Weedon, Joshua C. Randall, Willem H. Ouwehand, David P. Strachan, Nigel W. Rayner, Mark Walker, G. A. Hitman, Alex S. F. Doney, Colin N. A. Palmer, Andrew D. Morris, Andrew T. Hattersley, Eleftheria Zeggini, Timothy M. Frayling, Mark I. McCarthy

    Izdano 2008
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  10. 10
    A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

    A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates od Ioanna Tachmazidou, George Dedoussis, Lorraine Southam, Aliki‐Eleni Farmaki, Graham R. S. Ritchie, Dionysia K. Xifara, Angela Matchan, Konstantinos Hatzikotoulas, Nigel W. Rayner, Yuan Chen, Toni I. Pollin, Jeffrey R. O’Connell, Laura M. Yerges-Armstrong, Chrysoula Kiagiadaki, Kalliope Panoutsopoulou, Jeremy Schwartzentruber, Loukas Moutsianas, Emmanouil Tsafantakis, Chris Tyler‐Smith, Gil McVean, Yali Xue, Eleftheria Zeggini

    Izdano 2013
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  11. 11
    Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes

    Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes od Josine L. Min, Geoffrey C. Nicholson, Ingileif Halgrimsdottir, Kristian Almstrup, Andreas Petri, Amy Barrett, Mary E. Travers, Nigel W. Rayner, Reedik Mägi, Fredrik Pettersson, John Broxholme, Matt J. Neville, Quin F. Wills, Jane Cheeseman, Maxine Allen, Chris Holmes, Tim D. Spector, Jan Fleckner, Mark I. McCarthy, Fredrik Karpe, Cecilia M. Lindgren, Krina T. Zondervan

    Izdano 2012
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  12. 12
    Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

    Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants od Kalliope Panoutsopoulou, Konstantinos Hatzikotoulas, Dionysia K. Xifara, Vincenza Colonna, Aliki‐Eleni Farmaki, Graham R. S. Ritchie, Lorraine Southam, Arthur Gilly, Ioanna Tachmazidou, Segun Fatumo, Angela Matchan, Nigel W. Rayner, Ιωάννα Ντάλλα, Massimo Mezzavilla, Yuan Chen, Chrysoula Kiagiadaki, Eleni Zengini, Vasiliki Mamakou, Antonis Athanasiadis, Μαργαρίτα Γιαννακοπούλου, Vassiliki-Eirini Kariakli, Rebecca N. Nsubuga, Alex Karabarinde, Manjinder S. Sandhu, Gil McVean, Chris Tyler‐Smith, Emmanouil Tsafantakis, Maria Karaleftheri, Yali Xue, George Dedoussis, Eleftheria Zeggini

    Izdano 2014
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  13. 13
    Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

    Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes od Eleftheria Zeggini, Michael N. Weedon, Cecilia M. Lindgren, Timothy M. Frayling, Katherine S. Elliott, Hana Lango Allen, Nicholas J. Timpson, John R. B. Perry, Nigel W. Rayner, Rachel M. Freathy, Jeffrey C. Barrett, Beverley M. Shields, Andrew P. Morris, Sian Ellard, Christopher J. Groves, Lorna W. Harries, Jonathan Marchini, Katharine R. Owen, Beatrice Knight, Lon R. Cardon, Mark Walker, G. A. Hitman, Andrew D. Morris, Alex S. F. Doney, Mark I. McCarthy, Andrew T. Hattersley

    Izdano 2007
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  14. 14
    A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection

    A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection od Geoffrey C. Nicholson, Mattias Rantalainen, Jia V. Li, Anthony D. Maher, Daniel Malmodin, Kourosh R. Ahmadi, Johan H. Faber, Amy Barrett, Josine L. Min, Nigel W. Rayner, Henrik Toft, Maria Krestyaninova, Juris Vīksna, Sudeshna Guha Neogi, Marc‐Emmanuel Dumas, Uğis Sarkans, Peter Donnelly, Thomas Illig, Jerzy Adamski, Karsten Suhre, Maxine Allen, Krina T. Zondervan, Tim D. Spector, Jeremy K. Nicholson, John C. Lindon, Dorrit Baunsgaard, Elaine Holmes, Mark I. McCarthy, Chris Holmes

    Izdano 2011
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  15. 15
    A common variant of HMGA2 is associated with adult and childhood height in the general population

    A common variant of HMGA2 is associated with adult and childhood height in the general population od Michael N. Weedon, Guillaume Lettre, Rachel M. Freathy, Cecilia M. Lindgren, Benjamin F. Voight, John R. B. Perry, Katherine S. Elliott, Rachel Hackett, Candace Guiducci, Beverley M. Shields, Eleftheria Zeggini, Hana Lango Allen, Valeriya Lyssenko, Nicholas J. Timpson, Noël P. Burtt, Nigel W. Rayner, Richa Saxena, Kristin Ardlie, Jonathan H. Tobias, Andy Ness, Susan M. Ring, Colin N. A. Palmer, Andrew D. Morris, Leena Peltonen, Veikko Salomaa, George Davey Smith, Leif Groop, Andrew T. Hattersley, Mark I. McCarthy, Joel N. Hirschhorn, Timothy M. Frayling

    Izdano 2007
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  16. 16
    A Variant in MCF2L Is Associated with Osteoarthritis

    A Variant in MCF2L Is Associated with Osteoarthritis od Aaron Day-Williams, Lorraine Southam, Kalliope Panoutsopoulou, Nigel W. Rayner, Tõnu Esko, Karol Estrada, Hafdís T. Helgadóttir, Albert Hofman, T. Ingvarsson, Helgi Jónsson, Aime Keis, H. Kerkhof, Gudmar Thorleifsson, Nigel Arden, Andrew Carr, Kay Chapman, Panos Deloukas, John Loughlin, Andrew W. McCaskie, William Ollier, Stuart H. Ralston, Timothy D. Spector, Gillian A. Wallis, J. Mark Wilkinson, Nadim Aslam, Fraser Birell, Ian Carluke, John Joseph, Ashok Rai, Mike Reed, Kirsten Walker, Sally Doherty, Ingileif Jónsdóttir, Rose A. Maciewicz, Kenneth Muir, Andres Metspalu, Fernando Rivadeneira, Kāri Stefánsson, Unnur Styrkársdóttir, André G. Uitterlinden, Joyce B. J. van Meurs, Weiya Zhang, Ana M. Valdes, Michael Doherty, Eleftheria Zeggini

    Izdano 2011
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  17. 17
    A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

    A Common Variant in the <i>FTO</i> Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity od Timothy M. Frayling, Nicholas J. Timpson, Michael N. Weedon, Eleftheria Zeggini, Rachel M. Freathy, Cecilia M. Lindgren, John R. B. Perry, Katherine S. Elliott, Hana Lango Allen, Nigel W. Rayner, Beverley M. Shields, Lorna W. Harries, Jeffrey C. Barrett, Sian Ellard, Christopher J. Groves, Bridget Knight, Ann‐Marie Patch, Andy Ness, Shah Ebrahim, Debbie A. Lawlor, Susan M. Ring, Yoav Ben‐Shlomo, Marjo‐Riitta Järvelin, Ulla Sovio, Amanda J. Bennett, David Melzer, Luigi Ferrucci, Ruth J. F. Loos, Inês Barroso, Nicholas J. Wareham, Fredrik Karpe, Katharine R. Owen, Lon R. Cardon, Mark Walker, G. A. Hitman, Colin N. A. Palmer, Alex S. F. Doney, Andrew D. Morris, George Davey Smith, Andrew T. Hattersley, Mark I. McCarthy

    Izdano 2007
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  18. 18
    Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

    Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups od André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla Ivane Ganz Vogel, Timo D. Müller, Harald Grallert, H.‐Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo‐Riitta Järvelin, Anna‐Liisa Hartikainen, Claire Lévy‐Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kieß, Péter Kovács, Nigel W. Rayner, Inga Prokopenko, Mark I. McCarthy, H. Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M. Nöthen, Hae‐Won Uh, Raimund Erbel, Karl‐Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, Stephen Eyre

    Izdano 2010
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  19. 19
    The Genetic Landscape of Renal Complications in Type 1 Diabetes

    The Genetic Landscape of Renal Complications in Type 1 Diabetes od Niina Sandholm, Natalie Van Zuydam, Emma Ahlqvist, Thorhildur Juliusdottir, Harshal Deshmukh, Nigel W. Rayner, Barbara Di Camillo, Carol Forsblom, João Fadista, Daniel Ziemek, Rany M. Salem, Linda T. Hiraki, Marcus G. Pezzolesi, David‐Alexandre Trégouët, Emma H. Dahlström, Erkka Valo, Nikolay Oskolkov, Claes Ladenvall, M. Loredana Marcovecchio, Jason D. Cooper, Francesco Sambo, Alberto Malovini, Marco Manfrini, Amy Jayne McKnight, Maria Lajer, Valma Harjutsalo, Daniel Gordin, Maija Parkkonen, Valeriya Lyssenko, Paul McKeigue, Stephen S. Rich, M. Julia Brosnan, Eric B. Fauman, Riccardo Bellazzi, Peter Rossing, Samy Hadjadj, Andrzej S. Królewski, Andrew D. Paterson, Joel N. Hirschhorn, Alexander P. Maxwell, Claudio Cobelli, Helen M. Colhoun, Per‐Henrik Groop, Mark I. McCarthy, Per‐Henrik Groop

    Izdano 2016
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  20. 20
    The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

    The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits od Benjamin F. Voight, Hyun Min Kang, Jun Ding, Cameron D. Palmer, Carlo Sidore, Peter S. Chines, Noël P. Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M. Frayling, Iris M. Heid, Anne Jackson, Toby Johnson, Tuomas O. Kilpeläinen, Cecilia M. Lindgren, Andrew P. Morris, Inga Prokopenko, Joshua C. Randall, Richa Saxena, Nicole Soranzo, Elizabeth K. Speliotes, Tanya M. Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, Nigel W. Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J. F. Loos, Sekar Kathiresan, Patricia B. Munroe, Christopher Newton‐Cheh, Arne Pfeufer, Nilesh J. Samani, Heribert Schunkert, Joel N. Hirschhorn, David Altshuler, Mark I. McCarthy, Gonçalo R. Abecasis, Michael Boehnke

    Izdano 2012
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