Resultats de la cerca - Nicholas C. O. Tomkinson

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  1. 1
    Progress in the Development of non‐BET Bromodomain Chemical Probes

    Progress in the Development of non‐BET Bromodomain Chemical Probes per Natalie H. Theodoulou, Nicholas C. O. Tomkinson, Rab K. Prinjha, P. G. Humphreys

    Publicat 2016
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  2. 2
    A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis

    A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis per Cinta Diez-Ardanuy, Jennifer Greaves, Kevin R. Munro, Nicholas C. O. Tomkinson, Luke Chamberlain

    Publicat 2017
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  3. 3
    Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ-Lactones, Isobenzofuranones, and Tetrahydrofurans

    Alkene Dioxygenation with Malonoyl Peroxides: Synthesis of γ-Lactones, Isobenzofuranones, and Tetrahydrofurans per Carla Alamillo‐Ferrer, Marianna Karabourniotis‐Sotti, Alan R. Kennedy, Matthew Campbell, Nicholas C. O. Tomkinson

    Publicat 2016
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  4. 4
    Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry

    Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry per Jennifer Greaves, Kevin R. Munro, Stuart C. Davidson, Matthieu Rivière, Justyna Wojno, Terry Smith, Nicholas C. O. Tomkinson, Luke Chamberlain

    Publicat 2017
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  5. 5
    Mitokyne: A Ratiometric Raman Probe for Mitochondrial pH

    Mitokyne: A Ratiometric Raman Probe for Mitochondrial pH per Liam T. Wilson, William J. Tipping, Corinna Wetherill, Z.A. Henley, Karen Faulds, Duncan Graham, Simon P. Mackay, Nicholas C. O. Tomkinson

    Publicat 2021
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  6. 6
    Determination of Intracellular Esterase Activity Using Ratiometric Raman Sensing and Spectral Phasor Analysis

    Determination of Intracellular Esterase Activity Using Ratiometric Raman Sensing and Spectral Phasor Analysis per Henry J. Braddick, William J. Tipping, Liam T. Wilson, Harry S. Jaconelli, Emma K. Grant, Karen Faulds, Duncan Graham, Nicholas C. O. Tomkinson

    Publicat 2023
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  7. 7
    Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug–cell interactions

    Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug–cell interactions per William J. Tipping, Liam T. Wilson, Connie An, Aristea Anna Leventi, Alastair W. Wark, Corinna Wetherill, Nicholas C. O. Tomkinson, Karen Faulds, Duncan Graham

    Publicat 2022
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  8. 8
    A new class of ratiometric small molecule intracellular pH sensors for Raman microscopy

    A new class of ratiometric small molecule intracellular pH sensors for Raman microscopy per Liam T. Wilson, William J. Tipping, Lauren E. Jamieson, Corinna Wetherill, Z.A. Henley, Karen Faulds, Duncan Graham, Simon P. Mackay, Nicholas C. O. Tomkinson

    Publicat 2020
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  9. 9
    A direct-to-biology high-throughput chemistry approach to reactive fragment screening

    A direct-to-biology high-throughput chemistry approach to reactive fragment screening per Ross P. Thomas, Rachel E. Heap, Francesca Zappacosta, Emma K. Grant, Péter Pogány, Stephen Besley, David J. Fallon, Michael M. Hann, David House, Nicholas C. O. Tomkinson, Jacob T. Bush

    Publicat 2021
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  10. 10
    The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution

    The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution per Stacey A. Jones, Linda B. Moore, Jennifer L. Shenk, G. Bruce Wisely, Geraldine A. Hamilton, David D. McKee, Nicholas C. O. Tomkinson, Edward L. LeCluyse, Millard H. Lambert, Timothy M. Willson, Steven A. Kliewer, John T. Moore

    Publicat 2000
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  11. 11
    Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library

    Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library per Peter J. Brown, Tracey Smith-Oliver, Paul S. Charifson, Nicholas C. O. Tomkinson, Adam M. Fivush, Daniel D. Sternbach, Laura Wade, Lisa A. Orband‐Miller, Derek J. Parks, Steven G. Blanchard, Steven A. Kliewer, Jürgen M. Lehmann, Timothy M. Willson

    Publicat 1997
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  12. 12
    A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands

    A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands per Emma K. Grant, David J. Fallon, Michael M. Hann, Ken G. M. Fantom, Chad Quinn, Francesca Zappacosta, Roland S. Annan, Chun‐wa Chung, Paul Bamborough, David P. Dixon, Peter Stacey, David House, Vipulkumar K. Patel, Nicholas C. O. Tomkinson, Jacob T. Bush

    Publicat 2020
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  13. 13
    Optimized Chemical Probes for REV-ERBα

    Optimized Chemical Probes for REV-ERBα per Ryan P. Trump, Stefano Bresciani, Anthony W. J. Cooper, James P. Tellam, Justyna Wojno, John Blaikley, Lisa A. Orband‐Miller, Jennifer A. Kashatus, Mohamed Boudjelal, Helen C. Dawson, Andrew Loudon, David Ray, Daniel Grant, Stuart Farrow, Timothy M. Willson, Nicholas C. O. Tomkinson

    Publicat 2013
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  14. 14
    Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

    Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition per Natalie H. Theodoulou, Paul Bamborough, Andrew J. Bannister, Isabelle Becher, Rino A. Bit, Ka Hing, Chun‐wa Chung, Antje Dittmann, Gerard Drewes, David H. Drewry, Laurie Gordon, Paola Grandi, Melanie Leveridge, Matthew Lindon, Anne‐Marie Michon, Mária Judit Molnár, Samuel C. Robson, Nicholas C. O. Tomkinson, Tony Kouzarides, Rab K. Prinjha, P. G. Humphreys

    Publicat 2015
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  15. 15
    Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

    Fam49/CYRI interacts with Rac1 and locally suppresses protrusions per Loïc Fort, José Miguel Sebastiao Fernandes Batista, Peter A. Thomason, Heather J. Spence, Jamie Whitelaw, Luke Tweedy, Jennifer Greaves, Kirsty J. Martin, Kurt I. Anderson, Peter de Nully Brown, Sérgio Lilla, Matthew P. Neilson, Petra Tafelmeyer, Sara Zanivan, Shehab Ismail, David M. Bryant, Nicholas C. O. Tomkinson, Luke Chamberlain, Grant S. Mastick, Robert H. Insall, Laura M. Machesky

    Publicat 2018
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  16. 16
    Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

    Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation per Marie Pariollaud, Julie E. Gibbs, Thomas Hopwood, Sheila Brown, Nicola Begley, Ryan Vonslow, Toryn Poolman, Baoqiang Guo, Ben Saer, D. Heulyn Jones, James P. Tellam, Stefano Bresciani, Nicholas C. O. Tomkinson, Justyna Wojno-Picon, Anthony W. J. Cooper, Dion A. Daniels, Ryan P. Trump, Daniel Grant, William J. Zuercher, Timothy M. Willson, Andrew S. MacDonald, Brian Bolognese, Patricia L. Podolin, Yolanda Sánchez, Andrew Loudon, David Ray

    Publicat 2018
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