検索結果 - Nencka, Radim

Structural analysis of the putative SARS-CoV-2 primase complex 著者: Konkolova, Eva, Klima, Martin, Nencka, Radim, Boura, Evzen

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Structural analysis of the SARS-CoV-2 methyltransferase complex involved in RNA cap creation bound to sinefungin 著者: Krafcikova, Petra, Silhan, Jan, Nencka, Radim, Boura, Evzen

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Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses 著者: Eyer, Luděk, Nencka, Radim, de Clercq, Erik, Seley-Radtke, Katherine, Růžek, Daniel

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The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors 著者: Šebera, Jakub, Dubankova, Anna, Sychrovský, Vladimír, Ruzek, Daniel, Boura, Evzen, Nencka, Radim

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Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2′-C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection 著者: Eyer, Luděk, Fojtíková, Martina, Nencka, Radim, Rudolf, Ivo, Hubálek, Zdeněk, Ruzek, Daniel

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High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses 著者: Cihlova, Bara, Huskova, Andrea, Böserle, Jiri, Nencka, Radim, Boura, Evzen, Silhan, Jan

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In Vivo 5FU-Exposed Human Medullary Thyroid Carcinoma Cells Contain a Chemoresistant CD133+ Tumor–Initiating Cell Subset 著者: Kucerova, Lucia, Feketeova, Lucia, Kozovska, Zuzana, Poturnajova, Martina, Matuskova, Miroslava, Nencka, Radim, Babal, Pavel

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Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses 著者: Konkolova, Eva, Dejmek, Milan, Hřebabecký, Hubert, Šála, Michal, Böserle, Jiří, Nencka, Radim, Boura, Evzen

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Coronaviral RNA-methyltransferases: function, structure and inhibition 著者: Nencka, Radim, Silhan, Jan, Klima, Martin, Otava, Tomas, Kocek, Hugo, Krafcikova, Petra, Boura, Evzen

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Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein 著者: Dinesh, Dhurvas Chandrasekaran, Chalupska, Dominika, Silhan, Jan, Koutna, Eliska, Nencka, Radim, Veverka, Vaclav, Boura, Evzen

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The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine 著者: Šebera, Jakub, Hattori, Yoshikazu, Sato, Daichi, Řeha, David, Nencka, Radim, Kohno, Takashi, Kojima, Chojiro, Tanaka, Yoshiyuki, Sychrovský, Vladimír

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Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication 著者: Dejmek, Milan, Konkoľová, Eva, Eyer, Luděk, Straková, Petra, Svoboda, Pavel, Šála, Michal, Krejčová, Kateřina, Růžek, Daniel, Boura, Evzen, Nencka, Radim

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The crystal structure of the phosphatidylinositol 4-kinase IIα 著者: Baumlova, Adriana, Chalupska, Dominika, Róźycki, Bartosz, Jovic, Marko, Wisniewski, Eva, Klima, Martin, Dubankova, Anna, Kloer, Daniel P, Nencka, Radim, Balla, Tamas, Boura, Evzen

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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein 著者: Smola, Miroslav, Gutten, Ondrej, Dejmek, Milan, Kožíšek, Milan, Evangelidis, Thomas, Tehrani, Zahra Aliakbar, Novotná, Barbora, Nencka, Radim, Birkuš, Gabriel, Rulíšek, Lubomír, Boura, Evzen

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Nucleoside Inhibitors of Tick-Borne Encephalitis Virus 著者: Eyer, Luděk, Valdés, James J., Gil, Victor A., Nencka, Radim, Hřebabecký, Hubert, Šála, Michal, Salát, Jiří, Černý, Jiří, Palus, Martin, De Clercq, Erik, Růžek, Daniel

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Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors 著者: Šála, Michal, Kögler, Martin, Plačková, Pavla, Mejdrová, Ivana, Hřebabecký, Hubert, Procházková, Eliška, Strunin, Dmytro, Lee, Gary, Birkus, Gabriel, Weber, Jan, Mertlíková-Kaiserová, Helena, Nencka, Radim

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A novel and potent brain penetrant inhibitor of extracellular vesicle release 著者: Rojas, Camilo, Sala, Michal, Thomas, Ajit G., Datta Chaudhuri, Amrita, Yoo, Seung‐Wan, Li, Zhigang, Dash, Ranjeet P., Rais, Rana, Haughey, Norman J., Nencka, Radim, Slusher, Barbara

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Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein 著者: Klima, Martin, Tóth, Dániel J., Hexnerova, Rozalie, Baumlova, Adriana, Chalupska, Dominika, Tykvart, Jan, Rezabkova, Lenka, Sengupta, Nivedita, Man, Petr, Dubankova, Anna, Humpolickova, Jana, Nencka, Radim, Veverka, Vaclav, Balla, Tamas, Boura, Evzen

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A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha 著者: Sengupta, Nivedita, Jović, Marko, Barnaeva, Elena, Kim, David W., Hu, Xin, Southall, Noel, Dejmek, Milan, Mejdrova, Ivana, Nencka, Radim, Baumlova, Adriana, Chalupska, Dominika, Boura, Evzen, Ferrer, Marc, Marugan, Juan, Balla, Tamas

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Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer’s Disease 著者: Šála, Michal, Hollinger, Kristen R., Thomas, Ajit G., Dash, Ranjeet P., Tallon, Carolyn, Veeravalli, Vijayabhaskar, Lovell, Lyndah, Kögler, Martin, Hřebabecký, Hubert, Procházková, Eliška, Nešuta, Ondřej, Donoghue, Amanda, Lam, Jenny, Rais, Rana, Rojas, Camilo, Slusher, Barbara S., Nencka, Radim

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