نتائج البحث - Neil Parrott

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  1. 1
    Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

    Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects حسب Neil Parrott, Viera Lukáčová, Grazyna Fraczkiewicz, Michael B. Bolger

    منشور في 2009
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  2. 2
    Application of Full Physiological Models for Pharmaceutical Drug Candidate Selection and Extrapolation of Pharmacokinetics to Man

    Application of Full Physiological Models for Pharmaceutical Drug Candidate Selection and Extrapolation of Pharmacokinetics to Man حسب Neil Parrott, Hannah M. Jones, Nicolas Paquereau, Thierry Lavé

    منشور في 2005
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    Artigo
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  3. 3
    Physiologically Based Absorption Modeling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Alectinib

    Physiologically Based Absorption Modeling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Alectinib حسب Neil Parrott, Li Yu, Ryusuke Takano, Mikiko Nakamura, Peter N. Morcos

    منشور في 2016
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  4. 4
    Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies

    Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies حسب Neil A. Miller, Micaela B. Reddy, Aki T. Heikkinen, Viera Lukáčová, Neil Parrott

    منشور في 2019
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  5. 5
    IMPORTANCE OF MINIMIZING HLA-DR MISMATCH AND COLD PRESERVATION TIME IN CADAVERIC RENAL TRANSPLANTATION

    IMPORTANCE OF MINIMIZING HLA-DR MISMATCH AND COLD PRESERVATION TIME IN CADAVERIC RENAL TRANSPLANTATION حسب John Connolly, Philip Dyer, Susan Martin, Neil Parrott, Robert Pearson, Robert W. Johnson

    منشور في 1996
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    Artigo
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  6. 6
    Oral Absorption from Surfactant-Based Drug Formulations: The Impact of Molecularly Dissolved Drug on Bioavailability

    Oral Absorption from Surfactant-Based Drug Formulations: The Impact of Molecularly Dissolved Drug on Bioavailability حسب Florentin Lukas Holzem, Neil Parrott, Jeannine Petrig Schaffland, Martin Brandl, Annette Bauer‐Brandl, Cordula Stillhart

    منشور في 2024
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  7. 7
    Progress in Prediction and Interpretation of Clinically Relevant Metabolic Drug-Drug Interactions: a Minireview Illustrating Recent Developments and Current Opportunities

    Progress in Prediction and Interpretation of Clinically Relevant Metabolic Drug-Drug Interactions: a Minireview Illustrating Recent Developments and Current Opportunities حسب Stephen Fowler, Peter N. Morcos, Yumi Cleary, Meret Martin‐Facklam, Neil Parrott, Michael Gertz, Li Yu

    منشور في 2017
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  8. 8
    Physiologically Based Absorption Modelling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Entrectinib

    Physiologically Based Absorption Modelling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Entrectinib حسب Neil Parrott, Cordula Stillhart, Marc Lindenberg, Bjoern Wagner, Karey Kowalski, Elena Guerini, Nassim Djebli, Georgina Meneses‐Lorente

    منشور في 2020
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  9. 9
    Development of a Physiologically Based Model for Oseltamivir and Simulation of Pharmacokinetics in Neonates and Infants

    Development of a Physiologically Based Model for Oseltamivir and Simulation of Pharmacokinetics in Neonates and Infants حسب Neil Parrott, Brian E. Davies, Gerhard Hoffmann, Annette Koerner, Thierry Lavé, Eric Prinssen, Elizabeth Theogaraj, Thomas P. Singer

    منشور في 2011
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  10. 10
    Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review

    Impact of regional differences along the gastrointestinal tract of healthy adults on oral drug absorption: An UNGAP review حسب Maria Vertzoni, Patrick Augustijns, Michael Grimm, Mirko Koziolek, Glenn Lemmens, Neil Parrott, Christina Pentafragka, Christos Reppas, Jari Rubbens, Jens Van Den Αbeele, Tim Vanuytsel, Werner Weitschies, Clive Wilson

    منشور في 2019
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  11. 11
    Advancing Predictions of Tissue and Intracellular Drug Concentrations Using <i>In Vitro</i>, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

    Advancing Predictions of Tissue and Intracellular Drug Concentrations Using <i>In Vitro</i>, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches حسب Yingying Guo, Xiaoyan Chu, Neil Parrott, Kim L. R. Brouwer, Vicky Hsu, Swati Nagar, Pär Matsson, Pradeep Sharma, Jan Snoeys, Yuichi Sugiyama, Daniel Tatosian, Jashvant D. Unadkat, Shiew‐Mei Huang, Aleksandra Galetin

    منشور في 2018
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  12. 12
    Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic <scp>Physiologically‐Based Pharmacokinetic</scp> Model

    Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic <scp>Physiologically‐Based Pharmacokinetic</scp> Model حسب Yuan Chen, Tamara D. Cabalu, Ernesto Callegari, Heidi J. Einolf, Lichuan Liu, Neil Parrott, Sheila Annie Peters, Edgar Schuck, Pradeep Sharma, Helen Tracey, Vijay Upreti, Ming Zheng, Andy Z. X. Zhu, Stephen D. Hall

    منشور في 2019
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  13. 13
    Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling

    Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling حسب Nicole A. Kratochwil, Christophe Meille, Stephen Fowler, Florian Klammers, Aynur Ekiciler, Birgit Molitor, Sandrine Simon, Isabelle Walter, Claudia McGinnis, Johanna Walther, Brian C. Leonard, Miriam Triyatni, Hassan Javanbakht, Christoph Funk, Franz Schuler, Thierry Lavé, Neil Parrott

    منشور في 2017
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  14. 14
    Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

    Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective حسب Tycho Heimbach, Yuan Chen, Jun Chen, Vaishali Dixit, Neil Parrott, Sheila Annie Peters, Italo Poggesi, Pradeep Sharma, Jan Snoeys, Mohamad Shebley, Guoying Tai, Susanna Tse, Vijay Upreti, Ying‐Hong Wang, Alice Tsai, Binfeng Xia, Ming Zheng, Andy Z. X. Zhu, Stephen D. Hall

    منشور في 2020
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  15. 15
    Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

    Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review حسب Cordula Stillhart, Katarina Vučićević, Patrick Augustijns, Abdul W. Basit, Hannah Batchelor, Talia Flanagan, Ina Gesquiere, Rick Greupink, Dániel Keszthelyi, Mikko Koskinen, Christine M. Madla, Christophe Matthys, Goran Miljuš, Miriam G. Mooij, Neil Parrott, Anna‐Lena Ungell, Saskia N. de Wildt, Mine Orlu, Sandra Klein, Anette Müllertz

    منشور في 2020
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  16. 16
    A novel orally available small molecule that inhibits hepatitis B virus expression

    A novel orally available small molecule that inhibits hepatitis B virus expression حسب H. Mueller, Steffen Wildum, Souphalone Luangsay, Johanna Walther, Anaïs Lopez, Philipp Tropberger, Giorgio Ottaviani, Wenzhe Lu, Neil Parrott, Jitao David Zhang, Roland Schmucki, Tomáš Raček, Jean-Christophe Hoflack, Erich Kueng, Floriane Point, Xue Zhou, Guido Steiner, Marc Lütgehetmann, Gianna Rapp, Tassilo Volz, Maura Dandri, Yang Song, John A. T. Young, Hassan Javanbakht

    منشور في 2017
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  17. 17
    Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective

    Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective حسب Arian Emami Riedmaier, Kevin DeMent, James E. Huckle, Phil Bransford, Cordula Stillhart, Richard Lloyd, Ravindra V. Alluri, Sumit Basu, Yuan Chen, Varsha Dhamankar, Stephanie Dodd, Priyanka Kulkarni, Andrés Olivares‐Morales, Chi‐Chi Peng, Xavier Pépin, Xiaojun Ren, Thuy Tran, Christophe Tistaert, Tycho Heimbach, Filippos Kesisoglou, Christian Wagner, Neil Parrott

    منشور في 2020
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  18. 18
    Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression

    Pharmacology of Basimglurant (RO4917523, RG7090), a Unique Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator in Clinical Development for Depression حسب Lothar Lindemann, Richard H. Porter, Sebastian H. Scharf, Basil Kuennecke, Andreas Bruns, Markus von Kienlin, Anthony Harrison, Axel Paehler, Christoph Funk, Andreas Gloge, Manfred Schneider, Neil Parrott, Liudmila Polonchuk, U Niederhäuser, Stephen R. Morairty, Thomas S. Kilduff, Eric Vieira, Sabine Kolczewski, Juergen Wichmann, Thomas Härtung, Michael Honer, Edilio Borroni, Jean‐Luc Moreau, Eric Prinssen, Will Spooren, Joseph G. Wettstein, Georg Jaeschke

    منشور في 2015
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  19. 19
    The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

    The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group حسب Mirko Koziolek, Stefano Alcaro, Patrick Augustijns, Abdul W. Basit, Michael Grimm, Bart Hens, Caroline L. Hoad, Philipp Jedamzik, Christine M. Madla, Marc Maliepaard, Luca Marciani, Annalisa Maruca, Neil Parrott, Petr Pávek, Christopher J. H. Porter, Christos Reppas, Diana A. van Riet‐Nales, Jari Rubbens, Marina Statelova, Natalie L. Trevaskis, Kateřina Valentová, Maria Vertzoni, Dubravka Vitali Čepo, Maura Corsetti

    منشور في 2019
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  20. 20
    Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report

    Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report حسب Amitava Mitra, Sandra Suarez‐Sharp, Xavier Pépin, Talia Flanagan, Yang Zhao, Evangelos Kotzagiorgis, Neil Parrott, Satish Sharan, Christophe Tistaert, Tycho Heimbach, Banu S. Zolnik, Erik Sjögren, Fang Wu, Om Anand, Shefali Kakar, Min Li, Shereeni Veerasingham, Shinichi Kijima, Gustavo Mendes Lima Santos, Baoming Ning, Kimberly Raines, Greg Rullo, Haritha Mandula, Poonam Delvadia, Jennifer Dressman, Paul A. Dickinson, Andrew Babiskin

    منشور في 2020
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