Search Results - Navin Varadarajan

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  1. 1
    Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity

    Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity by Navin Varadarajan, Jongsik Gam, Mark Olsen, George Georgiou, Brent L. Iverson

    Published 2005
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  2. 2
    Highly active and selective endopeptidases with programmed substrate specificities

    Highly active and selective endopeptidases with programmed substrate specificities by Navin Varadarajan, Sarah Rodriguez, Bum-Yeol Hwang, George Georgiou, Brent L. Iverson

    Published 2008
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  3. 3
    Rapid, efficient functional characterization and recovery of HIV-specific human CD8 <sup>+</sup> T cells using microengraving

    Rapid, efficient functional characterization and recovery of HIV-specific human CD8 <sup>+</sup> T cells using microengraving by Navin Varadarajan, Douglas S. Kwon, Kenneth Law, Adebola O. Ogunniyi, Melis N. Anahtar, James M. Richter, Bruce D. Walker, J. Christopher Love

    Published 2012
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  4. 4
    Automated profiling of individual cell–cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING)

    Automated profiling of individual cell–cell interactions from high-throughput time-lapse imaging microscopy in nanowell grids (TIMING) by Amine Merouane, Nicolas Rey-Villamizar, Yanbin Lu, Ivan Liadi, Gabrielle Romain, Jennifer Lu, Harjeet Singh, Laurence J.N. Cooper, Navin Varadarajan, Badrinath Roysam

    Published 2015
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  5. 5
    Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells

    Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells by Xingyue An, Victor G. Sendra, Ivan Liadi, Balakrishnan Ramesh, Gabrielle Romain, Cara Haymaker, Melisa Martinez-Paniagua, Yanbin Lu, Laszlo Radvanyi, Badrinath Roysam, Navin Varadarajan

    Published 2017
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  6. 6
    Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2

    Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2 by Xingyue An, Melisa Martinez-Paniagua, Ali Rezvan, Samiur Rahman Sefat, Mohsen Fathi, Shailbala Singh, Sujit Biswas, Melissa Pourpak, Cassian Yee, Xinli Liu, Navin Varadarajan

    Published 2021
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  7. 7
    Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition

    Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition by Melisa J. Montalvo, Irfan Bandey, Ali Rezvan, Kwan-Ling Wu, Arash Saeedi, Rohan Kulkarni, Yongshuai Li, Xingyue An, K M Samiur Rahman Sefat, Navin Varadarajan

    Published 2024
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  8. 8
    Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils

    Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils by David S. Yang, Arash Saeedi, Aram Davtyan, Mohsen Fathi, Michael B. Sherman, Mohammad S. Safari, Alena Klindziuk, Michelle Barton, Navin Varadarajan, Anatoly B. Kolomeisky, Peter G. Vekilov

    Published 2021
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  9. 9
    Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells

    Antibody Fc engineering improves frequency and promotes kinetic boosting of serial killing mediated by NK cells by Gabrielle Romain, Vladimir Senyukov, Nicolas Rey-Villamizar, Amine Merouane, William Kelton, Ivan Liadi, Ankit Mahendra, Wissam Charab, George Georgiou, Badrinath Roysam, Dean A. Lee, Navin Varadarajan

    Published 2014
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  10. 10
    Individual Motile CD4+ T Cells Can Participate in Efficient Multikilling through Conjugation to Multiple Tumor Cells

    Individual Motile CD4+ T Cells Can Participate in Efficient Multikilling through Conjugation to Multiple Tumor Cells by Ivan Liadi, Harjeet Singh, Gabrielle Romain, Nicolas Rey-Villamizar, Amine Merouane, Jay R T. Adolacion, Partow Kebriaei, Helen Huls, Peng Qiu, Badrinath Roysam, Laurence J.N. Cooper, Navin Varadarajan

    Published 2015
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  11. 11
    Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia

    Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia by Junying Zheng, Wenjuan Ru, Jay R T. Adolacion, Michael S. Spurgat, Xin Liu, Subo Yuan, Rommel X. Liang, Jianli Dong, Andrew S. Potter, S. Steven Potter, Ken Chen, Rui Chen, Navin Varadarajan, Shao‐Jun Tang

    Published 2021
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  12. 12
    Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

    Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter by Krit Ritthipichai, Cara Haymaker, Melisa Martinez, Andrew Aschenbrenner, Xiaohui Yi, Minying Zhang, Charuta Kale, Luis M. Vence, Jason Roszik, Yared Hailemichael, Willem W. Overwijk, Navin Varadarajan, Roza Nurieva, Laszlo Radvanyi, Patrick Hwu, Chantale Bernatchez

    Published 2017
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  13. 13
    A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis

    A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis by Navin Varadarajan, Boris Jülg, Yvonne J. Yamanaka, Huabiao Chen, Adebola O. Ogunniyi, Elizabeth McAndrew, Lindsay C. Porter, Alicja Piechocka‐Trocha, Brenna J. Hill, Daniel C. Douek, Florencia Pereyra, Bruce D. Walker, J. Christopher Love

    Published 2011
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  14. 14
    A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens

    A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens by Christopher L. Yankaskas, Keyata N. Thompson, Colin D. Paul, Michele Vítolo, Panagiotis Mistriotis, Ankit Mahendra, Vivek K. Bajpai, Daniel J. Shea, Kristen M. Manto, Andreas C. Chai, Navin Varadarajan, Aikaterini Kontrogianni‐Konstantopoulos, Stuart S. Martin, Κωνσταντίνος Κωνσταντόπουλος

    Published 2019
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  15. 15
    High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

    High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire by Brandon J. DeKosky, Gregory C. Ippolito, Ryan Deschner, Jason J. Lavinder, Yariv Wine, Brandon Rawlings, Navin Varadarajan, Claudia Giesecke‐Thiel, Thomas Dörner, Sarah F. Andrews, Patrick C. Wilson, Scott Hunicke‐Smith, C. Grant Willson, Andrew D. Ellington, George Georgiou

    Published 2013
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  16. 16
    Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses

    Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses by Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan Bandey, Jay R T. Adolacion, Darren Heeke, Ivan Liadi, Mario L. Marques‐Piubelli, Luisa M. Solis, Ankit Mahendra, Francisco Vega, Laurence J.N. Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva S. Neelapu, Navin Varadarajan

    Published 2022
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  17. 17
    Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators

    Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators by Jiakai Hou, Yunfei Wang, Leilei Shi, Yuan Chen, Chunyu Xu, Arash Saeedi, Ke Pan, Ritu Bohat, Nicholas A. Egan, Jodi A. McKenzie, Rina M. Mbofung, Leila J. Williams, Zhenhuang Yang, Ming Sun, Xiaofang Liang, Jordi Rodón, Navin Varadarajan, Cassian Yee, Yiwen Chen, Patrick Hwu, Weiyi Peng

    Published 2021
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  18. 18
    Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters

    Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters by Ankita Leekha, Arash Saeedi, K M Samiur Rahman Sefat, Monish Kumar, Melisa Martinez-Paniagua, Adrian Damian, Rohan Kulkarni, Kate Reichel, Ali Rezvan, Shalaleh Masoumi, Xinli Liu, Laurence J.N. Cooper, Manu Sebastian, Courtney M. Sands, Vallabh E. Das, Nimesh B. Patel, Brett L. Hurst, Navin Varadarajan

    Published 2024
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  19. 19
    Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy

    Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy by Rama Soundararajan, Jared J. Fradette, Jessica Konen, Stacy L. Moulder, Xiang Zhang, Don L. Gibbons, Navin Varadarajan, Ignacio Wistuba, Debasish Tripathy, Chantale Bernatchez, Lauren A. Byers, Jeffrey S. Chang, Alejandro Contreras, Bora Lim, Edwin R. Parra, Emily Roarty, Jing Wang, Fei Yang, Michelle Barton, Jeffrey M. Rosen, Sendurai A. Mani

    Published 2019
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  20. 20
    IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

    IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions by Chang‐Han Lee, Gabrielle Romain, Wupeng Yan, Makiko Watanabe, Wissam Charab, Biliana Todorova, Jiwon Lee, Kendra Triplett, Moses Donkor, Oana I. Lungu, Anja Lux, Nicholas Marshall, Margaret A. Lindorfer, Odile Richard, Bianca Balbino, Tae Hyun Kang, Hidetaka Tanno, George Delidakis, Corrine Alford, Ronald P. Taylor, Falk Nimmerjahn, Navin Varadarajan, Pierre Bruhns, Yan Zhang, George Georgiou

    Published 2017
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