Resultados de procura - Natasha Sahgal

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  1. 1
    The histone demethylase<i>KDM3A</i>regulates the transcriptional program of the androgen receptor in prostate cancer cells

    The histone demethylase<i>KDM3A</i>regulates the transcriptional program of the androgen receptor in prostate cancer cells por Stephen Wilson, Lingling Fan, Natasha Sahgal, Jianfei Qi, Fabian V. Filipp

    Publicado 2017
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  2. 2
    Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

    Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival por Lingling Fan, Ge Peng, Natasha Sahgal, Ladan Fazli, Martin Gleave, Yuji Zhang, Arif Hussain, Jianfei Qi

    Publicado 2015
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  3. 3
    Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation

    Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation por Eileen McNeill, Mark J. Crabtree, Natasha Sahgal, Jyoti Patel, Surawee Chuaiphichai, Asif Iqbal, Ashley Hale, David R. Greaves, Keith M. Channon

    Publicado 2014
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  4. 4
    The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity

    The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity por Jianfei Qi, Manisha Tripathi, Rajeev Mishra, Natasha Sahgal, Ladan Fazil, Susan Ettinger, William J. Placzek, Giuseppina Claps, Leland W.K. Chung, David D.L. Bowtell, Martin Gleave, Neil A. Bhowmick, Ze’ev A. Ronai

    Publicado 2013
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  5. 5
    Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain

    Foxp2 Regulates Gene Networks Implicated in Neurite Outgrowth in the Developing Brain por Sonja C. Vernes, Peter L. Oliver, Elizabeth Spiteri, Helen Lockstone, Rathi Puliyadi, Jennifer M. Taylor, Joses Ho, Cédric Mombereau, Ariel Brewer, Ernesto Lowy, Jérôme Nicod, Matthias Groszer, Dilair Baban, Natasha Sahgal, Jean‐Baptiste Cazier, Jiannis Ragoussis, Kay E. Davies, Daniel H. Geschwind, Simon E. Fisher

    Publicado 2011
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  6. 6
    Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells

    Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells por L J Walker, Yu-Hoi Kang, Matthew O. Smith, H. Tharmalingham, Narayan Ramamurthy, Vicki M. Fleming, Natasha Sahgal, Alasdair Leslie, Ye Htun Oo, Alessandra Geremia, Thomas J. Scriba, Willem A. Hanekom, Georg M. Lauer, Olivier Lantz, David H. Adams, Fiona Powrie, Eleanor Barnes, Paul Klenerman

    Publicado 2011
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  7. 7
    Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

    Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells por Hamid Dolatshad, Andrea Pellagatti, Marta Fernández‐Mercado, Bon Ham Yip, Luca Malcovati, Martin Attwood, B Przychodzen, Natasha Sahgal, Alexander Kanapin, Helen Lockstone, Laura Scifo, Peter Vandenberghe, Elli Papaemmanuil, Christopher W. J. Smith, Peter J. Campbell, Shimpei Ogawa, Jaroslaw P. Maciejewski, Mario Cazzola, Kienan I. Savage, Jacqueline Boultwood

    Publicado 2014
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  8. 8
    Erratum: Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

    Erratum: Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells por Hamid Dolatshad, Andrea Pellagatti, Marta Fernández‐Mercado, Bon Ham Yip, Luca Malcovati, Martin Attwood, B Przychodzen, Natasha Sahgal, Alexander Kanapin, Helen Lockstone, Laura Scifo, Peter Vandenberghe, Elli Papaemmanuil, Christopher W. Smith, P.J. Campbell, Shimpei Ogawa, Jaroslaw P. Maciejewski, Mario Cazzola, Kienan I. Savage, Jacqueline Boultwood

    Publicado 2015
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  9. 9
    Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

    Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling por Julie Adam, Emine Hatipoglu, Linda O′Flaherty, Nicola Ternette, Natasha Sahgal, Helen Lockstone, Dilair Baban, Emma Nye, Gordon Stamp, Kathryn Wolhuter, Marcus Stevens, Román Fischer, Peter Carmeliet, Patrick H. Maxwell, Christopher W. Pugh, Norma Frizzell, Tomoyoshi Soga, Benedikt M. Kessler, Mona El‐Bahrawy, Peter J. Ratcliffe, Patrick J. Pollard

    Publicado 2011
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  10. 10
    CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

    CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages por Joannah R. Fergusson, Kira Smith, Vicki M. Fleming, Neil Rajoriya, Evan W. Newell, Ruth Simmons, Emanuele Marchi, Sophia Björkander, Yu-Hoi Kang, Leo Swadling, Ayako Kurioka, Natasha Sahgal, Helen Lockstone, Dilair Baban, Gordon J. Freeman, Eva Sverremark‐Ekström, Mark M. Davis, Miles P. Davenport, Vanessa Venturi, James E. Ussher, Christian B. Willberg, Paul Klenerman

    Publicado 2014
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  11. 11
    A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

    A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia por Julie Adam, Ming Yang, Christina Bauerschmidt, Mitsuhiro Kitagawa, Linda O′Flaherty, Pratheesh Maheswaran, Gizem Özkan, Natasha Sahgal, Dilair Baban, Keiko Kato, Kaori Saito, Keiko Iino, Kaori Igarashi, Michael R.L. Stratford, Christopher W. Pugh, Daniel A. Tennant, Christian Ludwig, Benjamin Davies, Peter J. Ratcliffe, Mona El‐Bahrawy, Houman Ashrafian, Tomoyoshi Soga, Patrick J. Pollard

    Publicado 2013
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  12. 12
    Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

    Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway por Houman Ashrafian, Gábor Czibik, Mohamed Bellahcene, Dunja Aksentijević, Anthony C. Smith, Sarah J. Mitchell, Michael S. Dodd, Jennifer Kirwan, Jonathan Byrne, Christian Ludwig, Henrik Isackson, Arash Yavari, Nicolaj B. Støttrup, Hussain Contractor, Thomas J. Cahill, Natasha Sahgal, Daniel R. Ball, Rune Isak Dupont Birkler, Iain P. Hargreaves, Daniel A. Tennant, John M. Land, Craig A. Lygate, Mogens Johannsen, Rajesh Kharbanda, Stefan Neubauer, Charles Redwood, Rafael de Cabo, Ismayil Ahmet, Mark I. Talan, Ulrich L. Günther, Alan J. Robinson, Mark R. Viant, Patrick J. Pollard, Damian J. Tyler, Hugh Watkins

    Publicado 2012
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  13. 13
    Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

    Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response por Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Giovanni Stracquadanio, Katherine A. Brown, P. Richter, Marsha D. Wallace, Elisabeth E. Bond, Natasha Sahgal, Samantha Moore, Svanhild Nornes, Sarah De Val, Mirvat Surakhy, David Sims, Xuting Wang, Douglas A. Bell, Jorge Zerón-Medina, Yanyan Jiang, Anderson J. Ryan, Joanna Selfe, Janet Shipley, Siddhartha Kar, Paul D.P. Pharoah, Chey Loveday, Rick Jansen, Lukasz F. Grochola, Claire Palles, Andrew Protheroe, Val Millar, Daniel Ebner, Meghana S. Pagadala, Sarah P. Blagden, Tim Maughan, Enric Domingo, Ian Tomlinson, Clare Turnbull, Hannah Carter, Gareth L. Bond

    Publicado 2021
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  14. 14
    Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

    Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden por Jean‐Baptiste Cazier, Srinivasa R. Rao, Chelsea McLean, Alexandra K. Walker, Ben Wright, E Jaeger, Christiana Kartsonaki, Luke Marsden, Christopher Yau, Carme Camps, Pamela J. Kaisaki, Christopher Allan, Moustafa Attar, John Bell, David L. Bentley, John Broxholme, David Buck, Jean‐Baptiste Cazier, Richard R. Copley, Richard J. Cornall, Peter Donnelly, Simon Fiddy, Angie Green, Lorna Gregory, Russell Grocock, Edouard Hatton, Chris Holmes, Linda Hughes, Peter Humburg, Sean Humphray, Alexander Kanapin, Zoya Kingsbury, Julian C. Knight, Sarah Lamble, Stefano Lise, Lorne Lonie, Gerton Lunter, Hilary C. Martin, Lisa Murray, Davis J. McCarthy, Gil McVean, Alistair T. Pagnamenta, Paolo Piazza, Guadelupe Polanco, Peter J. Ratcliffe, Andy Rimmer, Natasha Sahgal, Jenny C. Taylor, Ian Tomlinson, Amy Trebes, Andrew O.M. Wilkie, Ben Wright, Christopher Yau, Jenny C. Taylor, James W.F. Catto, Ian Tomlinson, Anne E. Kiltie, Freddie C. Hamdy

    Publicado 2014
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  15. 15
    Mammalian γ2 AMPK regulates intrinsic heart rate

    Mammalian γ2 AMPK regulates intrinsic heart rate por Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pintér, Neil Herring, Julia Jung, Kirill V. Tarasov, Emily J. Sharpe, Markus Wolfien, Gábor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R. St. Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D. Ziman, Jack M. Moen, Daniel R. Riordon, Christopher E. Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G. Matt, Yelena S. Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M. Siggs, John Gomes, H Muskett, Mahon L. Maguire, Youlia Beglov, Matt Kelly, Pedro Paulo Nascimento Santos, Nicola J. Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David Ferguson, Jürgen E. Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M. Channon, Richard J. Cornall, Eduardo Back Sternick, David J. Paterson, Charles Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G. Lakatta, Hugh Watkins, Houman Ashrafian

    Publicado 2017
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  16. 16
    Erythrocytosis associated with a novel missense mutation in the BPGM gene

    Erythrocytosis associated with a novel missense mutation in the BPGM gene por Nayia Petousi, Richard R. Copley, Terence R.J. Lappin, S.E. Haggan, Celeste Bento, Holger Cario, Melanie J. Percy, Peter J. Ratcliffe, Peter A. Robbins, M. F. McMullin, Peter Donnelly, John I. Bell, D. R. Bentley, Gil McVean, Peter J. Ratcliffe, Jenny C. Taylor, Andrew O.M. Wilkie, P. Donelly, John Broxholme, David Buck, Jean‐Baptiste Cazier, Richard J. Cornall, Lynn Gregory, Julian C. Knight, Gerton Lunter, Gil McVean, Ian Tomlinson, Andrew O.M. Wilkie, David Buck, Christopher Allan, Moustafa Attar, Andrew Green, Lynn Gregory, Sean Humphray, Zoya Kingsbury, Sarah Lamble, Lorne Lonie, Alistair T. Pagnamenta, Paolo Piazza, Guadelupe Polanco, Amy Trebes, Gil McVean, Peter Donnelly, Jean‐Baptiste Cazier, John Broxholme, Richard R. Copley, Simon Fiddy, Russell Grocock, Edouard Hatton, Chris Holmes, L. Hughes, Peter Humburg, Alexander Kanapin, Stefano Lise, Gerton Lunter, Hilary C. Martin, Lisa Murray, Davis J. McCarthy, Andy Rimmer, Natasha Sahgal, Bruce Wright, Christopher Yau

    Publicado 2014
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  17. 17
    Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Factors influencing success of clinical genome sequencing across a broad spectrum of disorders por Jenny C. Taylor, Hilary C. Martin, Stefano Lise, John Broxholme, Jean‐Baptiste Cazier, Andy Rimmer, Alexander Kanapin, Gerton Lunter, Simon Fiddy, Chris Allan, A.R. Aricescu, Moustafa Attar, Christian Babbs, Jennifer Becq, David Beeson, Celeste Bento, P Bignell, Edward Blair, Veronica J. Buckle, Katherine R. Bull, Ondřej Cais, Holger Cario, Helen Chapel, Richard R. Copley, Richard J. Cornall, Jude Craft, Karin Dahan, Emma E. Davenport, Calliope A. Dendrou, Olivier Devuyst, Aimée L Fenwick, Jonathan Flint, Lars Fugger, Rodney D. Gilbert, Anne Goriely, Angie Green, Ingo H. Greger, Russell Grocock, Anja V. Gruszczyk, Robert Hastings, Edouard Hatton, Douglas R. Higgs, Adrian V. S. Hill, Chris Holmes, Malcolm F. Howard, Linda Hughes, Peter Humburg, David H. Johnson, Fredrik Karpe, Zoya Kingsbury, Usha Kini, Julian C. Knight, Jonathan Krohn, Sarah Lamble, Craig B. Langman, Lorne Lonie, Joshua Luck, Davis J. McCarthy, Simon J. McGowan, Mary Frances McMullin, Kerry A. Miller, Lisa Murray, Andrea H. Németh, M. Andrew Nesbit, David Nutt, Elizabeth Ormondroyd, Annette Oturai, Alistair T. Pagnamenta, Smita Y. Patel, Melanie J. Percy, Nayia Petousi, Paolo Piazza, Siân E. Piret, Guadalupe Polanco‐Echeverry, Niko Popitsch, Fiona Powrie, Christopher W. Pugh, Lynn Quek, Peter A. Robbins, Kathryn Robson, Alexandra Russo, Natasha Sahgal, Pauline A. van Schouwenburg, Anna Schuh, Earl D. Silverman, Alison Simmons, Per Soelberg Sørensen, Elizabeth Sweeney, John Taylor, Rajesh V. Thakker, Ian Tomlinson, Amy Trebes, Stephen R.F. Twigg, Holm H. Uhlig, Paresh Vyas, Tim J. Vyse, Steven A. Wall, Hugh Watkins, Michael P. Whyte, Lorna Witty

    Publicado 2015
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