Resultados da pesquisa - Natalie Jäger

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  1. 1
    RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression

    RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression Por Pascal D. Johann, Natalie Jäger, Stefan M. Pfister, Martin Sill

    Publicado em 2019
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  2. 2
    Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

    Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution Por Hongcang Gu, Christoph Bock, Tarjei S. Mikkelsen, Natalie Jäger, Zachary D. Smith, Eleni M. Tomazou, Andreas Gnirke, Eric S. Lander, Alexander Meissner

    Publicado em 2010
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  3. 3
    Quantitative comparison of genome-wide DNA methylation mapping technologies

    Quantitative comparison of genome-wide DNA methylation mapping technologies Por Christoph Bock, Eleni M. Tomazou, Arie B. Brinkman, Fabian Müller, Femke Simmer, Hongcang Gu, Natalie Jäger, Andreas Gnirke, Hendrik G. Stunnenberg, Alexander Meissner

    Publicado em 2010
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  4. 4
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model

    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model Por Daniel Haag, Norman Mack, Patricia Benites Goncalves da Silva, Britta Statz, Jessica Clark, Koji Tanabe, Tanvi Sharma, Natalie Jäger, David Jones, Daisuke Kawauchi, Marius Wernig, Stefan M. Pfister

    Publicado em 2021
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  5. 5
    Heterozygous <i>BRCA1</i> and <i>BRCA2</i> and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer

    Heterozygous <i>BRCA1</i> and <i>BRCA2</i> and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer Por Christian P. Kratz, Dmitrii Smirnov, Robert J. Autry, Natalie Jäger, Sebastian M. Waszak, Anika Großhennig, Riccardo Berutti, Mareike Wendorff, Pierre Hainaut, Stefan M. Pfister, Holger Prokisch, Tim Ripperger, David Malkin

    Publicado em 2022
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  6. 6
    Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies

    Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies Por Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul A. Northcott, Barbara Hutter, Natalie Jäger, Marcel Kool, Michael D. Taylor, Peter Lichter, Stefan M. Pfister, Stephan Wolf, Benedikt Brors, Roland Eils

    Publicado em 2013
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  7. 7
    Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers

    Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers Por Venu Thatikonda, S. M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne Gröbner, Gregor Warsow, Barbara Hutter, Daniel Hüebschmann, Stefan Fröhling, Marcel Kool, Mirjam Blattner-Johnson, David Jones, Ludmil B. Alexandrov, Stefan M. Pfister, Natalie Jäger

    Publicado em 2023
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  8. 8
    Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

    Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes Por Tanvi Sharma, Ed C. Schwalbe, Daniel Williamson, Martin Sill, Volker Hovestadt, Martin Mynarek, Stefan Rutkowski, Giles Robinson, Amar Gajjar, Florence M.G. Cavalli, Vijay Ramaswamy, Michael D. Taylor, Janet C. Lindsey, Rebecca M. Hill, Natalie Jäger, Andrey Korshunov, Debbie Hicks, Simon Bailey, Marcel Kool, Lukas Chávez, Paul A. Northcott, Stefan M. Pfister, Steven C. Clifford

    Publicado em 2019
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  9. 9
    Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci

    Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci Por Sima J. Zacharek, Christine M. Fillmore, Allison N. Lau, David W. Gludish, Alan Y. Chou, Joshua W. K. Ho, Raffaella Zamponi, Roi Gazit, Christoph Bock, Natalie Jäger, Zachary D. Smith, Tae‐Min Kim, Arven Saunders, Janice Siu Chong Wong, Joo‐Hyeon Lee, Rebecca R. Roach, Derrick J. Rossi, Alex Meissner, Alexander A. Gimelbrant, Peter J. Park, Carla F. Kim

    Publicado em 2011
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  10. 10
    Germline <i>GPR161</i> Mutations Predispose to Pediatric Medulloblastoma

    Germline <i>GPR161</i> Mutations Predispose to Pediatric Medulloblastoma Por Matthias Begemann, Sebastian M. Waszak, Giles Robinson, Natalie Jäger, Tanvi Sharma, Cordula Knopp, Florian Kraft, Olga Moser, Martin Mynarek, Léa Guerrini‐Rousseau, Laurence Brugières, Pascale Varlet, Torsten Pietsch, Daniel C. Bowers, Murali Chintagumpala, Felix Sahm, Jan O. Korbel, Stefan Rutkowski, Thomas Eggermann, Amar Gajjar, Paul A. Northcott, Miriam Elbracht, Stefan M. Pfister, Udo Kontny, Ingo Kurth

    Publicado em 2019
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  11. 11
    Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM

    Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry... Por Anna-Elisa Heipertz, Kristian W. Pajtler, Elke Pfaff, Kathrin Schramm, Mirjam Blattner-Johnson, Till Milde, Barbara C. Jones, Cecilia Zuliani, Caroline Hutter, Olli Lohi, Antonis Kattamis, Iwona Dachowska-Kałwak, Anna Nilsson, Nicolas U. Gerber, Karin P.S. Langenberg, Bianca F. Goemans, C. Michel Zwaan, Jan J. Molenaar, Natalie Jäger, Uta Dirksen, Ruth Witt, Stefan M. Pfister, David Jones, Annette Kopp‐Schneider, Olaf Witt, Cornelis M. van Tilburg

    Publicado em 2023
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  12. 12
    Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

    Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer Por Natalie Jäger, Matthias Schlesner, David Jones, Simon Raffel, Jan‐Philipp Mallm, Kristin M. Junge, Dieter Weichenhan, Tobias Bauer, Naveed Ishaque, Marcel Kool, Paul A. Northcott, Andrey Korshunov, Ruben M. Drews, Jan Köster, Rogier Versteeg, Julia Richter, Michael Hummel, Stephen C. Mack, Michael D. Taylor, Hendrik Witt, Benedict Swartman, Dietrich Schulte-Bockholt, Marc Sultan, Marie‐Laure Yaspo, Hans Lehrach, Barbara Hutter, Benedikt Brors, Stephan Wolf, Christoph Plass, Reiner Siebert, Andreas Trumpp, Karsten Rippe, Irina Lehmann, Peter Lichter, Stefan M. Pfister, Roland Eils

    Publicado em 2013
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  13. 13
    Mapping pediatric brain tumors to their origins in the developing cerebellum

    Mapping pediatric brain tumors to their origins in the developing cerebellum Por Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, Martin Sill, Pengbo Beck, Kenneth Chun‐Ho Chan, Andrey Korshunov, Felix Sahm, Maximilian Deng, Dominik Sturm, John DeSisto, Andrew M. Donson, Nicholas K. Foreman, Adam L. Green, Giles Robinson, Brent A. Orr, Qingsong Gao, Emily Darrow, Jennifer Hadley, Paul A. Northcott, Johannes Gojo, Daisuke Kawauchi, Volker Hovestadt, Mariella G. Filbin, Andreas von Deimling, Marc Zuckermann, Kristian W. Pajtler, Marcel Kool, David Jones, Natalie Jäger, Lena M. Kutscher, Henrik Kaessmann, Stefan M. Pfister

    Publicado em 2023
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  14. 14
    Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

    Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations Por Trevor J. Pugh, Shyamal Dilhan Weeraratne, Tenley C. Archer, Daniel A. Pomeranz Krummel, Daniel Auclair, James Bochicchio, Mauricio O. Carneiro, Scott L. Carter, Kristian Cibulskis, Rachel Erlich, Heidi Greulich, Michael S. Lawrence, Niall J. Lennon, Aaron McKenna, James C. Meldrim, Alex H. Ramos, Michael Ross, Carsten Russ, Erica Shefler, Andrey Sivachenko, Brian Sogoloff, Petar Stojanov, Pablo Tamayo, Jill P. Mesirov, Vladimir Amani, Natalia Teider, Soma Sengupta, Jessica Pierre Francois, Paul A. Northcott, Michael D. Taylor, Furong Yu, Robert H. Crabtree, Amanda G. Kautzman, Stacey Gabriel, Gad Getz, Natalie Jäger, David Jones, Peter Lichter, Stefan M. Pfister, Thomas M. Roberts, Matthew Meyerson, Scott L. Pomeroy, Yoon‐Jae Cho

    Publicado em 2012
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  15. 15
    Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM

    Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM Por Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yannick Berker, Mirjam Blattner-Johnson, Kathrin Schramm, Barbara C. Jones, David Reuß, Laura Turunen, Aileen Friedenauer, Tim Holland‐Letz, Martin Sill, Lena Weiser, Christopher Previti, Gnanaprakash Balasubramanian, Nicolas U. Gerber, Johannes Gojo, Caroline Hutter, Ingrid Øra, Olli Lohi, Antonis Kattamis, Bram De Wilde, Frank Westermann, Stephan Tippelt, Norbert Graf, Michaela Nathrath, Monika Sparber‐Sauer, Astrid Sehested, Christof M. Kramm, Uta Dirksen, Olli Kallioniemi, Stefan M. Pfister, Cornelis M. van Tilburg, David Jones, Jani Saarela, Vilja Pietiäinen, Natalie Jäger, Matthias Schlesner, Annette Kopp‐Schneider, Sina Oppermann, Till Milde, Olaf Witt, Ina Oehme

    Publicado em 2022
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  16. 16
    Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

    Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations Por Tobias Rausch, David Jones, Marc Zapatka, Adrian M. Stütz, Thomas Zichner, Joachim Weischenfeldt, Natalie Jäger, Marc Remke, David Shih, Paul A. Northcott, Elke Pfaff, Jelena Tica, Qi Wang, Luca Massimi, Hendrik Witt, Sebastian Bender, Sabrina Pleier, Huriye Cin, Cynthia Hawkins, Christian Beck, Andreas von Deimling, Volkmar Hans, Benedikt Brors, Roland Eils, Wolfram Scheurlen, Jonathon Blake, Vladimı́r Beneš, Andreas E. Kulozik, Olaf Witt, Dianna C. Martin, Cindy Zhang, Rinnat M. Porat, Diana M. Merino, Jonathan D. Wasserman, Nada Jabado, Adam M. Fontebasso, Lars Bullinger, Frank G. Rücker, Konstanze Döhner, Hartmut Döhner, Jan Köster, Jan J. Molenaar, Rogier Versteeg, Marcel Kool, Uri Tabori, David Malkin, Andrey Korshunov, Michael D. Taylor, Peter Lichter, Stefan M. Pfister, Jan O. Korbel

    Publicado em 2012
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  17. 17
    Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

    Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer Por Joachim Weischenfeldt, Ronald Simon, Lars Feuerbach, Karin Schlangen, Dieter Weichenhan, Sarah Minner, Daniela Wuttig, Hans-Jörg Warnatz, Henning Stehr, Tobias Rausch, Natalie Jäger, Lei Gu, Olga Bogatyrova, Adrian M. Stütz, Rainer Claus, Roland Eils, Roland Eils, Clarissa Gerhäuser, Po-Hsien Huang, Barbara Hutter, Rolf Kabbe, Christian Lawerenz, Sylwester Radomski, Cynthia C. Bartholomae, Maria Fälth, Stephan Gade, Manfred Schmidt, Nina Amschler, Thomas Haß, Rami Galal, Jovisa Gjoni, Ruprecht Kuner, Constance Baer, Sawinee Masser, Christof von Kalle, Thomas Zichner, Vladimı́r Beneš, Benjamin Raeder, Malte Mäder, Vyacheslav Amstislavskiy, Meryem Avci, Hans Lehrach, Dmitri Parkhomchuk, Marc Sultan, Lia Burkhardt, Markus Graefen, Hartwig Huland, Martina Kluth, Antje Krohn, Hüseyin Sirma, Laura Stumm, Stefan Steurer, Katharina Grupp, Holger Sültmann, Guido Sauter, Christoph Plass, Benedikt Brors, Marie-Laure Yaspo, Jan O. Korbel, Thorsten Schlomm

    Publicado em 2013
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  18. 18
    3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma

    3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma Por Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana S. Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocío Acuña‐Hidalgo, Derek A. Reid, Kristin Sikkink, Monika Mauermann, Edwin F. Juarez, Anne Jenseit, James Robinson, Kristian W. Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G. Coufal, Michael L. Levy, Denise Malicki, Charlotte A. Hobbs, Stephen F. Kingsmore, Shareef Nahas, Matija Snuderl, John R. Crawford, Robert J. Wechsler‐Reya, Tom B. Davidson, Jennifer Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony D. Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin Kumar, Michael D. Taylor, Jeremy N. Rich, Frank Buchholz, Jill P. Mesirov, Stefan M. Pfister, Ferhat Ay, Jesse R. Dixon, Marcel Kool, Lukas Chávez

    Publicado em 2023
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  19. 19
    Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology

    Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology Por Dominik Sturm, David Capper, Felipe Andreiuolo, Marco Gessi, Christian Kölsche, Annekathrin Reinhardt, Philipp Sievers, Annika K. Wefers, Azadeh Ebrahimi, Abigail K. Suwala, Gerrit H. Gielen, Martin Sill, Daniel Schrimpf, Damian Stichel, Volker Hovestadt, Bjarne Daenekas, Agata Rode, Stefan Hamelmann, Christopher Previti, Natalie Jäger, Ivo Buchhalter, Mirjam Blattner-Johnson, Barbara C. Jones, Monika Warmuth‐Metz, Brigitte Bison, Kerstin Grund, Christian Sutter, Steffen Hirsch, Nicola Dikow, Martin Hasselblatt, Ulrich Schüller, Arend Koch, Nicolas U. Gerber, Christine L. White, Molly K. Buntine, Kathryn M. Kinross, Elizabeth M. Algar, Jordan R. Hansford, Nicholas G. Gottardo, Martin U. Schuhmann, Ulrich W. Thomale, Pablo Hernáiz Driever, Astrid Gnekow, Olaf Witt, Hermann L. Müller, Gabriele Calaminus, Gudrun Fleischhack, Uwe Kordes, Martin Mynarek, Stefan Rutkowski, Michael C. Frühwald, Christof M. Kramm, Andreas von Deimling, Torsten Pietsch, Felix Sahm, Stefan M. Pfister, David Jones

    Publicado em 2023
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  20. 20
    Germline Elongator mutations in Sonic Hedgehog medulloblastoma

    Germline Elongator mutations in Sonic Hedgehog medulloblastoma Por Sebastian M. Waszak, Giles Robinson, Brian Gudenas, Kyle Smith, Antoine Forget, Marija Kojic, Jesús García-López, Jennifer Hadley, Kayla V. Hamilton, Émilie Indersie, Ivo Buchhalter, Jules N. A. Kerssemakers, Natalie Jäger, Tanvi Sharma, Tobias Rausch, Marcel Kool, Dominik Sturm, David Jones, Aksana Vasilyeva, Ruth Tatevossian, Geoffrey Neale, Bérangère Lombard, Damarys Loew, Joy Nakitandwe, Michael Rusch, Daniel C. Bowers, Anne Bendel, Sonia Partap, Murali Chintagumpala, John R. Crawford, Nicholas G. Gottardo, Amy Smith, Christelle Dufour, Stefan Rutkowski, Tone Eggen, Finn Wesenberg, Kristina Kjærheim, Maria Feychting, Birgitta Lannering, Joachim Schüz, Christoffer Johansen, Tina Veje Andersen, Martin Röösli, Claudia E. Kuehni, Michael Grotzer, Marc Remke, Stéphanie Puget, Kristian W. Pajtler, Till Milde, Olaf Witt, Marina Ryzhova, Andrey Korshunov, Brent A. Orr, David W. Ellison, Laurence Brugières, Peter Lichter, Kim E. Nichols, Amar Gajjar, Brandon J. Wainwright, Olivier Ayrault, Jan O. Korbel, Paul A. Northcott, Stefan M. Pfister

    Publicado em 2020
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