Výsledky vyhledávání - Natalia Issaeva

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  1. 1
    EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations

    EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations Autor Hina Rehmani, Natalia Issaeva

    Vydáno 2020
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  2. 2
    HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis

    HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis Autor Cassie Pan, Natalia Issaeva, Wendell G. Yarbrough

    Vydáno 2018
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    Revisão
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  3. 3
    Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

    Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair Autor Eva Petermann, Manuel Luís Orta, Natalia Issaeva, Niklas Schultz, Thomas Helleday

    Vydáno 2010
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  4. 4
    Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide

    Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide Autor Natalia Issaeva, Assaf Friedler, Przemyslaw Bozko, Klas G. Wiman, Alan R. Fersht, Galina Selivanova

    Vydáno 2003
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  5. 5
    <i>TRAF3/CYLD</i> mutations identify a distinct subset of human papillomavirus‐associated head and neck squamous cell carcinoma

    <i>TRAF3/CYLD</i> mutations identify a distinct subset of human papillomavirus‐associated head and neck squamous cell carcinoma Autor Michael Hajek, Andrew Sewell, Susan M. Kaech, Barbara Burtness, Wendell G. Yarbrough, Natalia Issaeva

    Vydáno 2017
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  6. 6
    Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival

    Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival Autor Evgenia Gubanova, Brandee Brown, Sergey V. Ivanov, Thomas Helleday, Gordon B. Mills, Wendell G. Yarbrough, Natalia Issaeva

    Vydáno 2012
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  7. 7
    PRIMA-1<sup>Met</sup>/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo

    PRIMA-1<sup>Met</sup>/APR-246 induces wild-type p53-dependent suppression of malignant melanoma tumor growth in 3D culture and in vivo Autor Wenjie Bao, Ming Chen, Xu Zhao, Rajiv Kumar, Clemens Spinnler, Minna Thullberg, Natalia Issaeva, Galina Selivanova, Staffan Strömblad

    Vydáno 2011
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  8. 8
    Reactivation of Mutant p53 and Induction of Apoptosis in Human Tumor Cells by Maleimide Analogs

    Reactivation of Mutant p53 and Induction of Apoptosis in Human Tumor Cells by Maleimide Analogs Autor Vladimir J.N. Bykov, Natalia Issaeva, Nicole Zache, Alexandre Shilov, Monica Hultcrantz, Jan Bergman, Galina Selivanova, Klas G. Wiman

    Vydáno 2005
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  9. 9
    Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer

    Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer Autor Andrew Sewell, Brandee Brown, Asel Biktasova, Gordon B. Mills, Yiling Lu, Darren R. Tyson, Natalia Issaeva, Wendell G. Yarbrough

    Vydáno 2014
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  10. 10
    PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

    PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination Autor Helen E. Bryant, Eva Petermann, Niklas Schultz, Ann‐Sofie Jemth, Olga Loseva, Natalia Issaeva, Fredrik Johansson, Serena Fernandez, Peter McGlynn, Thomas Helleday

    Vydáno 2009
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  11. 11
    APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma

    APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma Autor Vincent L. Cannataro, Stephen G. Gaffney, Tomoaki Sasaki, Natalia Issaeva, Nicholas Grewal, Jennifer R. Grandis, Wendell G. Yarbrough, Barbara Burtness, Karen S. Anderson, Jeffrey P. Townsend

    Vydáno 2019
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  12. 12
    ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

    ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis Autor Yao Shi, Fedor Nikulenkov, Joanna Zawacka‐Pankau, Haitao Li, Razif R. Gabdoulline, Jianqiang Xu, Sofi Eriksson, Elisabeth Hedström, Natalia Issaeva, Alexander Kel, Elias S.J. Arnér, Galina Selivanova

    Vydáno 2014
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  13. 13
    Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer

    Demethylation Therapy as a Targeted Treatment for Human Papillomavirus–Associated Head and Neck Cancer Autor Asel Biktasova, Michael Hajek, Andrew K. Sewell, Cyril Gary, Gary Bellinger, Hari A. Deshpande, Aarti Bhatia, Barbara Burtness, Benjamin L. Judson, Saral Mehra, Wendell G. Yarbrough, Natalia Issaeva

    Vydáno 2017
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  14. 14
    TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

    TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior Autor Sergey V. Ivanov, Alexander Panaccione, Brandee Brown, Yan Guo, Christopher A. Moskaluk, Michael J. Wick, Jeffrey L. Brown, Alla V. Ivanova, Natalia Issaeva, Adel K. El‐Naggar, Wendell G. Yarbrough

    Vydáno 2012
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  15. 15
    Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers

    Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers Autor Jialing Zhang, Chien‐Jen Chen, Xinping Yang, Hui Cheng, Stephan S. Späth, Paúl E. Clavijo, Jianhong Chen, Christopher Silvin, Natalia Issaeva, Xiulan Su, Wendell G. Yarbrough, Christina M. Annunziata, Zhong Chen, Carter Van Waes

    Vydáno 2018
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  16. 16
    Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers

    Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers Autor Hui Cheng, Xinping Yang, Han Si, Anthony D. Saleh, Wenming Xiao, Jamie Coupar, Susanne M. Gollin, Robert L. Ferris, Natalia Issaeva, Wendell G. Yarbrough, Mark E. Prince, Thomas E. Carey, Carter Van Waes, Zhong Chen

    Vydáno 2018
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  17. 17
    Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck

    Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck Autor Jong Woo Lee, Janaki Parameswaran, Teresa Sandoval-Schaefer, Kyung Jin Eoh, Dong‐Hua Yang, Fang Zhu, Ranee Mehra, Roshan Sharma, Stephen G. Gaffney, Elizabeth B. Perry, Jeffrey P. Townsend, Ilya G. Serebriiskii, Erica A. Golemis, Natalia Issaeva, Wendell G. Yarbrough, Ja Seok Koo, Barbara Burtness

    Vydáno 2019
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  18. 18
    6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance

    6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance Autor Natalia Issaeva, Huw D. Thomas, Tatjana Djurenovic, Janneke E. Jaspers, Ivaylo Stoimenov, Suzanne Kyle, Nicholas Pedley, Ponnari Gottipati, Rafal Zur, Kate Sleeth, Vicky Chatzakos, Evan A. Mulligan, Cecilia Lundin, Evgenia Gubanova, Ariena Kersbergen, Adrian L. Harris, Ricky A. Sharma, Sven Rottenberg, Nicola J. Curtin, Thomas Helleday

    Vydáno 2010
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  19. 19
    Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma

    Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma Autor Daniel R. Carter, Jayne Murray, Belamy B. Cheung, Laura D. Gamble, Jessica Koach, Joanna Tsang, Selina K. Sutton, Heyam Kalla, Sarah Syed, Andrew J. Gifford, Natalia Issaeva, Asel Biktasova, Bernard Atmadibrata, Yuting Sun, Nicolas Sokolowski, Dora Ling, Patrick Y. Kim, Hannah Webber, Ashleigh Clark, Michelle Ruhle, Bing Liu, André Oberthuer, Matthias Fischer, Jennifer A. Byrne, Federica Saletta, Le Myo Thwe, Andrei A. Purmal, Gary Haderski, Catherine A. Burkhart, Frank Speleman, Katleen De Preter, Anneleen Beckers, David S. Ziegler, Tao Liu, Katerina V. Gurova, Andrei V. Gudkov, Murray D. Norris, Michelle Haber, Glenn M. Marshall

    Vydáno 2015
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  20. 20
    Characterization of HPV and host genome interactions in primary head and neck cancers

    Characterization of HPV and host genome interactions in primary head and neck cancers Autor Michael Parfenov, Chandra Sekhar Pedamallu, Nils Gehlenborg, Samuel S. Freeman, Ludmila Danilova, Christopher A. Bristow, Semin Lee, Angela Hadjipanayis, Elena Ivanova, Matthew D. Wilkerson, Alexei Protopopov, Lixing Yang, Sahil Seth, Xingzhi Song, Jiabin Tang, Xiaojia Ren, Jianhua Zhang, Angeliki Pantazi, Netty Santoso, Andrew Wei Xu, Harshad S. Mahadeshwar, David A. Wheeler, Robert I. Haddad, Joonil Jung, Akinyemi I. Ojesina, Natalia Issaeva, Wendell G. Yarbrough, D. Neil Hayes, Jennifer R. Grandis, Adel K. El‐Naggar, Matthew Meyerson, Peter J. Park, Lynda Chin, Jonathan G. Seidman, Peter S. Hammerman, Raju Kucherlapati, Adrian Ally, Miruna Balasundaram, İnanç Birol, Reanne Bowlby, Yaron S.N. Butterfield, Rebecca Carlsen, Dean Cheng, Andy Chu, Noreen Dhalla, Ranabir Guin, Robert A. Holt, Steven J.M. Jones, Darlene Lee, Haiyan I. Li, Marco A. Marra, Michael Mayo, Richard A. Moore, Andrew J. Mungall, A. Gordon Robertson, Jacqueline E. Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Tina Wong, Alexei Protopopov, Netty Santoso, Semin Lee, Michael Parfenov, Jianhua Zhang, Harshad S. Mahadeshwar, Jiabin Tang, Xiaojia Ren, Sahil Seth, Psalm Haseley, Dong Zeng, Lixing Yang, Andrew Wei Xu, Xingzhi Song, Angeliki Pantazi, Christopher A. Bristow, Angela Hadjipanayis, Jonathan G. Seidman, Lynda Chin, Peter J. Park, Raju Kucherlapati, Rehan Akbani, Tod D. Casasent, Wenbin Liu, Yiling Lu, Gordon B. Mills, Thomas Motter, John N. Weinstein, Lixia Diao, Jing Wang, You Hong Fan, Jinze Liu, Kai Wang, J. Todd Auman, Saianand Balu, Tom Bodenheimer, Elizabeth Buda, D. Neil Hayes, Katherine A. Hoadley, Alan P. Hoyle

    Vydáno 2014
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