Canlyniadau Chwilio - Mouscadet, Jean-Francois

Raltegravir: molecular basis of its mechanism of action gan Mouscadet, Jean-François, Tchertanov, Luba

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Chemistry and Structure-Activity Relationship of the Styrylquinoline-Type HIV Integrase Inhibitors gan Mouscadet, Jean-François, Desmaële, Didier

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Integrase and integration: biochemical activities of HIV-1 integrase gan Delelis, Olivier, Carayon, Kevin, Saïb, Ali, Deprez, Eric, Mouscadet, Jean-François

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Structure–Activity Relationship Studies of HIV-1 Integrase Oligonucleotide Inhibitors gan Agapkina, Julia, Zatsepin, Timofei, Knyazhanskaya, Ekaterina, Mouscadet, Jean-Francois, Gottikh, Marina

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Disulfide-Linked Integrase Oligomers Involving C280 Residues Are Formed In Vitro and In Vivo but Are Not Essential for Human Immunodeficiency Virus Replication gan Bischerour, Julien, Leh, Hervé, Deprez, Eric, Brochon, Jean-Claude, Mouscadet, Jean-François

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A novel function for spumaretrovirus integrase: an early requirement for integrase-mediated cleavage of 2 LTR circles gan Delelis, Olivier, Petit, Caroline, Leh, Herve, Mbemba, Gladys, Mouscadet, Jean-François, Sonigo, Pierre

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A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain gan Carayon, Kevin, Leh, Hervé, Henry, Etienne, Simon, Françoise, Mouscadet, Jean-François, Deprez, Eric

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The (52–96) C-terminal domain of Vpr stimulates HIV-1 IN-mediated homologous strand transfer of mini-viral DNA gan Bischerour, Julien, Tauc, Patrick, Leh, Hervé, de Rocquigny, Hugues, Roques, Bernard, Mouscadet, Jean-François

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Efficient and Specific Internal Cleavage of a Retroviral Palindromic DNA Sequence by Tetrameric HIV-1 Integrase gan Delelis, Olivier, Parissi, Vincent, Leh, Hervé, Mbemba, Gladys, Petit, Caroline, Sonigo, Pierre, Deprez, Eric, Mouscadet, Jean-François

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DNA binding induces dissociation of the multimeric form of HIV-1 integrase: A time-resolved fluorescence anisotropy study gan Deprez, Eric, Tauc, Patrick, Leh, Hervé, Mouscadet, Jean-François, Auclair, Christian, Hawkins, Mary E., Brochon, Jean-Claude

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G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not gan Ni, Xiao-Ju, Delelis, Olivier, Charpentier, Charlotte, Storto, Alexandre, Collin, Gilles, Damond, Florence, Descamps, Diane, Mouscadet, Jean-François

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Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase, RNase H, and Integrase Activities by Hydroxytropolones gan Didierjean, Joël, Isel, Catherine, Querré, Flore, Mouscadet, Jean-François, Aubertin, Anne-Marie, Valnot, Jean-Yves, Piettre, Serge R., Marquet, Roland

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The G140S mutation in HIV integrases from raltegravir-resistant patients rescues catalytic defect due to the resistance Q148H mutation gan Delelis, Olivier, Malet, Isabelle, Na, Li, Tchertanov, Luba, Calvez, Vincent, Marcelin, Anne-Genevieve, Subra, Frederic, Deprez, Eric, Mouscadet, Jean-François

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G140S mutation rescues HIV-1 IN integration defect due to Q148H in vitro and in vivo gan Delelis, Olivier, Malet, Isabelle, Tchertanov, Luba, Na, Li, Calvez, Vincent, Marcellin, Anne-Geneviève, Subra, Frédéric, Deprez, Eric, Mouscadet, Jean-Francois

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In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors gan Ni, Xiaoju, Abdel-Azeim, Safwat, Laine, Elodie, Arora, Rohit, Osemwota, Osamuede, Marcelin, Anne-Geneviève, Calvez, Vincent, Mouscadet, Jean-François, Tchertanov, Luba

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Structural basis for HIV-1 DNA integration in the human genome gan Michel, Fabrice, Eiler, Sylvia, Granger, Florence, Mouscadet, Jean-François, Gottikh, Marina, Nazabal, Alexis, Emiliani, Stéphane, Benarous, Richard, Moras, Dino, Schultz, Patrick, Ruff, Marc

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Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents gan Bonnenfant, Sabine, Thomas, Claire Marie, Vita, Claudio, Subra, Frédéric, Deprez, Eric, Zouhiri, Fatima, Desmaële, Didier, d'Angelo, Jean, Mouscadet, Jean François, Leh, Hervé

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The engagement of activating FcgammaRs inhibits primate lentivirus replication in human macrophages gan David, Annie, Sáez-Cirión, Asier, Versmisse, Pierre, Malbec, Odile, Iannascoli, Bruno, Herschke, Florence, Lucas, Marianne, Barré-Sinoussi, Françoise, Mouscadet, Jean-François, Daëron, Marc, Pancino, Gianfranco

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A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA gan Lyonnais, Sébastien, Gorelick, Robert J., Heniche-Boukhalfa, Fatima, Bouaziz, Serge, Parissi, Vincent, Mouscadet, Jean-François, Restle, Tobias, Gatell, Jose Maria, Le Cam, Eric, Mirambeau, Gilles

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Ku80 Participates in the Targeting of Retroviral Transgenes to the Chromatin of CHO Cells gan Masson, Christel, Bury-Moné, Stéphanie, Guiot, Elvire, Saez-Cirion, Asier, Schoëvaërt-Brossault, Damien, Brachet-Ducos, Corinne, Delelis, Olivier, Subra, Frédéric, Jeanson-Leh, Laurence, Mouscadet, Jean-François

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