檢索結果 - Moskophidis, Demetrius

Contribution of  Virus-specific CD8(+) Cytotoxic T Cells to Virus Clearance or Pathologic Manifestations of Influenza Virus Infection in a T Cell Receptor Transgenic Mouse Model 由 Moskophidis, Demetrius, Kioussis, Dimitris

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Insights into Regulation and Function of the Major Stress-Induced hsp70 Molecular Chaperone In Vivo: Analysis of Mice with Targeted Gene Disruption of the hsp70.1 or hsp70.3 Gene 由 Huang, Lei, Mivechi, Nahid F., Moskophidis, Demetrius

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Loss of Hsp110 Leads to Age-Dependent Tau Hyperphosphorylation and Early Accumulation of Insoluble Amyloid β 由 Eroglu, Binnur, Moskophidis, Demetrius, Mivechi, Nahid F.

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Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome 由 Jin, Xiongjie, Moskophidis, Demetrius, Mivechi, Nahid F.

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Targeted replacement of HSF1 phosphorylation sites at S303/S307 with alanine residues in mice increases cell proliferation and drug resistance 由 Jin, Xiongjie, Moskophidis, Demetrius, Mivechi, Nahid F.

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The Role of Alpha/Beta and Gamma Interferons in Development of Immunity to Influenza A Virus in Mice 由 Price, Graeme E., Gaszewska-Mastarlarz, Anna, Moskophidis, Demetrius

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Critical Role for Alpha/Beta and Gamma Interferons in Persistence of Lymphocytic Choriomeningitis Virus by Clonal Exhaustion of Cytotoxic T Cells 由 Ou, Rong, Zhou, Shenghua, Huang, Lei, Moskophidis, Demetrius

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Critical Role for Perforin-, Fas/FasL-, and TNFR1-Mediated Cytotoxic Pathways in Down-Regulation of Antigen-Specific T Cells during Persistent Viral Infection 由 Zhou, Shenghua, Ou, Rong, Huang, Lei, Moskophidis, Demetrius

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Control of Virus-Specific CD8(+) T-Cell Exhaustion and Immune-Mediated Pathology by E3 Ubiquitin Ligase Cbl-b during Chronic Viral Infection 由 Ou, Rong, Zhang, Menghua, Huang, Lei, Moskophidis, Demetrius

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Targeted Deletion of Hsf1, 2, and 4 Genes in Mice 由 Jin, Xiongjie, Eroglu, Binnur, Moskophidis, Demetrius, Mivechi, Nahid F.

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Targeted deletion of Hsf1, 2, and 4 genes in mice 由 Jin, Xiongjie, Eroglu, Binnur, Moskophidis, Demetrius, Mivechi, Nahid F.

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Modulation of Heat Shock Factor 1 Activity through Silencing of Ser303/Ser307 Phosphorylation Supports a Metabolic Program Leading to Age-Related Obesity and Insulin Resistance 由 Jin, Xiongjie, Qiao, Aijun, Moskophidis, Demetrius, Mivechi, Nahid F.

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Perforin and Fas Cytolytic Pathways Coordinately Shape the Selection and Diversity of CD8(+)-T-Cell Escape Variants of Influenza Virus 由 Price, Graeme E., Huang, Lei, Ou, Rong, Zhang, Menghua, Moskophidis, Demetrius

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Viral Escape by Selection of Cytotoxic T Cell–Resistant Variants in Influenza a Virus Pneumonia 由 Price, Graeme E., Ou, Rong, Jiang, Hong, Huang, Lei, Moskophidis, Demetrius

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Heat shock factor 1 deficiency via its downstream target gene αB-crystallin (Hspb5) impairs p53 degradation 由 Jin, Xiongjie, Moskophidis, Demetrius, Hu, Yanzhong, Phillips, Andrew, Mivechi, Nahid F.

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Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis 由 Xi, Caixia, Hu, Yanzhong, Buckhaults, Phillip, Moskophidis, Demetrius, Mivechi, Nahid F.

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Differential Tissue-Specific Regulation of Antiviral CD8(+) T-Cell Immune Responses during Chronic Viral Infection 由 Zhou, Shenghua, Ou, Rong, Huang, Lei, Price, Graeme E., Moskophidis, Demetrius

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The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis 由 Qiao, Aijun, Jin, Xiongjie, Pang, Junfeng, Moskophidis, Demetrius, Mivechi, Nahid F.

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Inactivation of Heat Shock Factor Hsf4 Induces Cellular Senescence and Suppresses Tumorigenesis In Vivo 由 Jin, Xiongjie, Eroglu, Binnur, Cho, Wonkyoung, Yamaguchi, Yukihiro, Moskophidis, Demetrius, Mivechi, Nahid F.

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The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular... 由 Cho, Wonkyoung, Jin, Xiongjie, Pang, Junfeng, Wang, Yan, Mivechi, Nahid F., Moskophidis, Demetrius

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