Resultats de la cerca - Monther Abu-Remaileh

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  1. 1
    An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

    An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis per Kıvanç Birsoy, Timothy C. Wang, Walter W. Chen, Elizaveta Freinkman, Monther Abu-Remaileh, David M. Sabatini

    Publicat 2015
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  2. 2
    Ferroptosis regulation by the NGLY1/NFE2L1 pathway

    Ferroptosis regulation by the NGLY1/NFE2L1 pathway per Giovanni C. Forcina, Lauren Pope, Magdalena Murray, Wentao Dong, Monther Abu-Remaileh, Carolyn R. Bertozzi, Scott J. Dixon

    Publicat 2022
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  3. 3
    Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling

    Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling per Monther Abu-Remaileh, Ariela Gerson, Marganit Farago, Gili Nathan, Irit Alkalay, Sharon Zins Rousso, Michal Gur, Abraham Fainsod, Yehudit Bergman

    Publicat 2010
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  4. 4
    Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase

    Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase per Jason R. Cantor, Monther Abu-Remaileh, Naama Kanarek, Elizaveta Freinkman, Xin Gao, Abner Louissaint, Caroline A. Lewis, David M. Sabatini

    Publicat 2017
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  5. 5
    Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

    Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes per Monther Abu-Remaileh, Gregory A. Wyant, Choah Kim, Nouf N. Laqtom, Maria Abbasi, Sze Ham Chan, Elizaveta Freinkman, David M. Sabatini

    Publicat 2017
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  6. 6
    De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

    De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes per Silvina Epsztejn‐Litman, Nirit Feldman, Monther Abu-Remaileh, Yoel Shufaro, Ariela Gerson, Jun Ueda, Rachel Deplus, François Fuks, Yoichi Shinkai, Howard Cedar, Yehudit Bergman

    Publicat 2008
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  7. 7
    mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient

    mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient per Gregory A. Wyant, Monther Abu-Remaileh, Rachel L. Wolfson, Walter W. Chen, Elizaveta Freinkman, Laura V. Danai, Matthew G. Vander Heiden, David M. Sabatini

    Publicat 2017
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  8. 8
    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein

    Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein per David A. Armenta, Nouf N. Laqtom, Grace Alchemy, Wentao Dong, Danielle Morrow, Carson D. Poltorack, David A. Nathanson, Monther Abu-Remaileh, Scott J. Dixon

    Publicat 2022
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  9. 9
    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease

    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease per Kwamina Nyame, Andy Hims, Aya Aburous, Nouf N. Laqtom, Wentao Dong, Uche N. Medoh, Julia C. Heiby, Jian Xiong, Alessandro Ori‬‬, Monther Abu-Remaileh

    Publicat 2024
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  10. 10
    Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer

    Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer per Monther Abu-Remaileh, Sebastian Bender, Günter Raddatz, Ihab Ansari, Daphne Cohen, Julian Gutekunst, Tanja Musch, Heinz Linhart, Achim Breiling, Eli Pikarsky, Yehudit Bergman, Frank Lyko

    Publicat 2015
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  11. 11
    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation

    An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation per Samantha G. Scharenberg, Wentao Dong, Ali Ghoochani, Kwamina Nyame, Roni Levin‐Konigsberg, Aswini R. Krishnan, Eshaan S. Rawat, Kaitlyn Spees, Michael C. Bassik, Monther Abu-Remaileh

    Publicat 2023
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  12. 12
    NUFIP1 is a ribosome receptor for starvation-induced ribophagy

    NUFIP1 is a ribosome receptor for starvation-induced ribophagy per Gregory A. Wyant, Monther Abu-Remaileh, Evgeni M. Frenkel, Nouf N. Laqtom, Vimisha Dharamdasani, Caroline A. Lewis, Sze Ham Chan, Ivonne Heinze, Alessandro Ori‬‬, David M. Sabatini

    Publicat 2018
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  13. 13
    Histidine catabolism is a major determinant of methotrexate sensitivity

    Histidine catabolism is a major determinant of methotrexate sensitivity per Naama Kanarek, Heather R. Keys, Jason R. Cantor, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Elizaveta Freinkman, Lawrence D. Schweitzer, David M. Sabatini

    Publicat 2018
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  14. 14
    Golgi-IP, a tool for multimodal analysis of Golgi molecular content

    Golgi-IP, a tool for multimodal analysis of Golgi molecular content per Rotimi Fasimoye, Wentao Dong, Raja Sekhar Nirujogi, Eshaan S. Rawat, Miharu Iguchi, Kwamina Nyame, Toan K. Phung, Enrico Bagnoli, Alan R. Prescott, Dario R. Alessi, Monther Abu-Remaileh

    Publicat 2023
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  15. 15
    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation per Ross Weber, Frederick S. Yen, Shirony P.V. Nicholson, Hanan Alwaseem, Erol C. Bayraktar, Mohammad Atif Alam, Rebecca C. Timson, Konnor La, Monther Abu-Remaileh, Henrik Molina, Kıvanç Birsoy

    Publicat 2020
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  16. 16
    Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates

    Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates per Zhou Yu, Lauren E. Surface, Chong Yon Park, Max A. Horlbeck, Gregory A. Wyant, Monther Abu-Remaileh, Timothy R. Peterson, David M. Sabatini, Jonathan S. Weissman, Erin K. O’Shea

    Publicat 2018
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  17. 17
    MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

    MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo per Erol C. Bayraktar, Lou Baudrier, Ceren Özerdem, Caroline A. Lewis, Sze Ham Chan, Tenzin Kunchok, Monther Abu-Remaileh, Andrew L. Cangelosi, David M. Sabatini, Kıvanç Birsoy, Walter W. Chen

    Publicat 2018
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  18. 18
    Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

    Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity per Yong Yu, Shihong Max Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jia‐Ming Liu, Bentian Jing, Qian Zhao, David M. Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C. Wang

    Publicat 2024
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  19. 19
    R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response

    R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response per Magdalena P. Crossley, Chenlin Song, M Bocek, Jun‐Hyuk Choi, Joseph N. Kousouros, Ataya Sathirachinda, Cindy Lin, Joshua R. Brickner, Gongshi Bai, Hannes Lans, Wim Vermeulen, Monther Abu-Remaileh, Karlene A. Cimprich

    Publicat 2022
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  20. 20
    CNS-wide repopulation by hematopoietic-derived microglia-like cells corrects progranulin deficiency in mice

    CNS-wide repopulation by hematopoietic-derived microglia-like cells corrects progranulin deficiency in mice per Pasqualina Colella, Ruhi Sayana, María Valentina Suárez-Nieto, Jolanda Sarno, Kwamina Nyame, Jian Xiong, Luisa Natália Pimentel Vera, Jessica Arozqueta Basurto, Marco Corbo, Anay Limaye, Kara L. Davis, Monther Abu-Remaileh, Natalia Gomez‐Ospina

    Publicat 2024
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