Resultats de la cerca - Mohammad A. Mandegar

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  1. 1
    Mitotic recombination counteracts the benefits of genetic segregation

    Mitotic recombination counteracts the benefits of genetic segregation per Mohammad A. Mandegar, Sarah P. Otto

    Publicat 2007
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  2. 2
    Haploids adapt faster than diploids across a range of environments

    Haploids adapt faster than diploids across a range of environments per Aleeza C. Gerstein, L. A. CLEATHERO, Mohammad A. Mandegar, Sarah P. Otto

    Publicat 2010
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  3. 3
    A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing

    A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing per Mahnaz Maddah, Julia D. Heidmann, Mohammad A. Mandegar, Chase D. Walker, Sara Bolouki, Bruce R. Conklin, Kevin Loewke

    Publicat 2015
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  4. 4
    Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes

    Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes per Alexandre J. S. Ribeiro, Olivier Schwab, Mohammad A. Mandegar, Yen-Sin Ang, Bruce R. Conklin, Deepak Srivastava, Beth L. Pruitt

    Publicat 2017
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  5. 5
    Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload

    Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload per Zhen Ma, Nathaniel Huebsch, Sang-Mo Koo, Mohammad A. Mandegar, Brian Siemons, Steven Boggess, Bruce R. Conklin, Costas P. Grigoropoulos, Kevin E. Healy

    Publicat 2018
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  6. 6
    Polo-like kinase inhibitors increase AAV production by halting cell cycle progression

    Polo-like kinase inhibitors increase AAV production by halting cell cycle progression per Krishna J. Fisher, Francis Grafton, Francesca Ispaso, Joshua Tworig, Rupert Derler, Florian Sonntag, Markus Hörer, Andreas Schulze, Christopher A. Reid, Mohammad A. Mandegar

    Publicat 2025
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  7. 7
    Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

    Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes per Francis Grafton, Jaclyn J. Ho, Sara Ranjbarvaziri, Farshad Farshidfar, Anastasiia Budan, Stephanie Steltzer, Mahnaz Maddah, Kevin Loewke, Kristina Green, Snahel Patel, Tim Hoey, Mohammad A. Mandegar

    Publicat 2021
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  8. 8
    A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress

    A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress per Luke M. Judge, Juan A. Pérez-Bermejo, Annie Truong, Alexandre J. S. Ribeiro, Jennie Yoo, Christina L Jensen, Mohammad A. Mandegar, Nathaniel Huebsch, Robyn M. Kaake, Po-Lin So, Deepak Srivastava, Beth L. Pruitt, Nevan J. Krogan, Bruce R. Conklin

    Publicat 2017
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  9. 9
    Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification

    Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification per Stephen L. Trisno, Katherine E. D. Philo, Kyle W. McCracken, Emily M. Catá, Sonya Ruiz-Torres, Scott A. Rankin, Lu Han, Talia Nasr, Praneet Chaturvedi, Marc E. Rothenberg, Mohammad A. Mandegar, Susanne I. Wells, Aaron M. Zorn, James M. Wells

    Publicat 2018
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  10. 10
    Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice

    Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice per Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Ana Budan, Emma Xu, Reva Shenwai, Matthew Kozubov, Cindy Li, Melissa Van Pell, Francis Grafton, Charles Mackay, Xiaomei Song, James R. Priest, Gretchen Argast, Mohammad A. Mandegar, Timothy Hoey, Jin Yang

    Publicat 2024
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  11. 11
    CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

    CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells per Siyuan Liu, Max A. Horlbeck, Seung Woo Cho, Harjus Birk, Martina Malatesta, Daniel He, Frank J. Attenello, Jacqueline E. Villalta, Min Y. Cho, Yuwen Chen, Mohammad A. Mandegar, Michael Olvera, Luke A. Gilbert, Bruce R. Conklin, Howard Y. Chang, Jonathan S. Weissman, Daniel A. Lim

    Publicat 2016
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  12. 12
    Deep profiling reveals substantial heterogeneity of integration outcomes in CRISPR knock-in experiments

    Deep profiling reveals substantial heterogeneity of integration outcomes in CRISPR knock-in experiments per Hera Canaj, Jeffrey A. Hussmann, Han Li, Kyle A. Beckman, Leeanne Goodrich, Nathan Cho, Yucheng J. Li, Daniel A. Santos, Aaron McGeever, Edna M. Stewart, Veronica Pessino, Mohammad A. Mandegar, Cindy Huang, Li Gan, Barbara Panning, Bo Huang, Jonathan S. Weissman, Manuel D. Leonetti

    Publicat 2019
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  13. 13
    Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses

    Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses per Nathaniel Huebsch, Peter Loskill, Nikhil Deveshwar, C. Ian Spencer, Luke M. Judge, Mohammad A. Mandegar, Cade B. Fox, Tamer M Mohamed, Zhen Ma, Anurag Mathur, Alice Sheehan, Annie Truong, Mike Saxton, Jennie Yoo, Deepak Srivastava, Tejal A. Desai, Po-Lin So, Kevin E. Healy, Bruce R. Conklin

    Publicat 2016
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  14. 14
    Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

    Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system per Michael J. Workman, Maxime M. Mahé, Stephen L. Trisno, Holly M. Poling, Carey L. Watson, Nambirajan Sundaram, Ching‐Fang Chang, Jacqueline V. Schiesser, P. Aubert, Edouard G. Stanley, Andrew G. Elefanty, Yuichiro Miyaoka, Mohammad A. Mandegar, Bruce R. Conklin, Michel Neunlist, Samantha A. Brugmann, Michael A. Helmrath, James M. Wells

    Publicat 2016
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  15. 15
    CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

    CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs per Mohammad A. Mandegar, Nathaniel Huebsch, Ekaterina B. Frolov, Edward Shin, Annie Truong, Michael Olvera, Amanda H. Chan, Yuichiro Miyaoka, Kristin Holmes, C. Ian Spencer, Luke M. Judge, David E. Gordon, Tilde V. Eskildsen, Jacqueline E. Villalta, Max A. Horlbeck, Luke A. Gilbert, Nevan J. Krogan, Søren P. Sheikh, Jonathan S. Weissman, Lei S. Qi, Po-Lin So, Bruce R. Conklin

    Publicat 2016
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