Resultados da pesquisa - Mireille Dumoulin

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  1. 1
    Normal and Aberrant Biological Self-Assembly: Insights from Studies of Human Lysozyme and Its Amyloidogenic Variants

    Normal and Aberrant Biological Self-Assembly: Insights from Studies of Human Lysozyme and Its Amyloidogenic Variants Por Mireille Dumoulin, Janet R. Kumita, Christopher M. Dobson

    Publicado em 2006
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  2. 2
    Protein Engineering Strategies for Improved Pharmacokinetics

    Protein Engineering Strategies for Improved Pharmacokinetics Por Aurélie Rondon, Sohaib Mahri, Francisco Morales-Yánez, Mireille Dumoulin, Rita Vanbever

    Publicado em 2021
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  3. 3
    Modeling Parkinson’s Disease With the Alpha-Synuclein Protein

    Modeling Parkinson’s Disease With the Alpha-Synuclein Protein Por Mónica Gómez-Benito, Noelia Granado, Patricia García‐Sanz, Anne Michel, Mireille Dumoulin, Rosario Moratalla

    Publicado em 2020
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  4. 4
    Activation of innate immunity by lysozyme fibrils is critically dependent on cross-β sheet structure

    Activation of innate immunity by lysozyme fibrils is critically dependent on cross-β sheet structure Por Adelin Gustot, Vincent Raussens, Morgane Dehousse, Mireille Dumoulin, Clare Bryant, Jean‐Marie Ruysschaert, Caroline Lonez

    Publicado em 2013
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  5. 5
    Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis

    Identification of the Core Structure of Lysozyme Amyloid Fibrils by Proteolysis Por Erica Frare, Maria F. Mossuto, Patrizia Polverino de Laureto, Mireille Dumoulin, Christopher M. Dobson, Angelo Fontana

    Publicado em 2006
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  6. 6
    Single‐domain antibody fragments with high conformational stability

    Single‐domain antibody fragments with high conformational stability Por Mireille Dumoulin, Katja Conrath, Annemie Van Meirhaeghe, Filip Meersman, Karel Heremans, Leon Frenken, Serge Muyldermans, Lode Wyns, André Matagne

    Publicado em 2002
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  7. 7
    Characterization of Oligomeric Species on the Aggregation Pathway of Human Lysozyme

    Characterization of Oligomeric Species on the Aggregation Pathway of Human Lysozyme Por Erica Frare, Maria F. Mossuto, Patrizia Polverino de Laureto, Serena Tolin, Linda Menzer, Mireille Dumoulin, Christopher M. Dobson, Angelo Fontana

    Publicado em 2009
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  8. 8
    Disulfide Bonds Reduce the Toxicity of the Amyloid Fibrils Formed by an Extracellular Protein

    Disulfide Bonds Reduce the Toxicity of the Amyloid Fibrils Formed by an Extracellular Protein Por Maria F. Mossuto, Benedetta Bolognesi, Bernat Guixer, Anne Dhulesia, Federico Agostini, Janet R. Kumita, Gian Gaetano Tartaglia, Mireille Dumoulin, Christopher M. Dobson, Xavier Salvatella

    Publicado em 2011
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  9. 9
    Reduced Global Cooperativity is a Common Feature Underlying the Amyloidogenicity of Pathogenic Lysozyme Mutations

    Reduced Global Cooperativity is a Common Feature Underlying the Amyloidogenicity of Pathogenic Lysozyme Mutations Por Mireille Dumoulin, Denis Canet, A. Last, Els Pardon, David B. Archer, Serge Muyldermans, Lode Wyns, André Matagne, Carol V. Robinson, Christina Redfield, Christopher M. Dobson

    Publicado em 2004
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  10. 10
    Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution

    Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution Por Anne Dhulesia, Nunilo Cremades, Janet R. Kumita, Shang‐Te Danny Hsu, Maria F. Mossuto, Mireille Dumoulin, Daniel Nietlispach, Mikael Akke, Xavier Salvatella, Christopher M. Dobson

    Publicado em 2010
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  11. 11
    The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity

    The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity Por Maria F. Mossuto, Anne Dhulesia, Glyn L. Devlin, Erica Frare, Janet R. Kumita, Patrizia Polverino de Laureto, Mireille Dumoulin, Angelo Fontana, Christopher M. Dobson, Xavier Salvatella

    Publicado em 2010
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  12. 12
    Population of Nonnative States of Lysozyme Variants Drives Amyloid Fibril Formation

    Population of Nonnative States of Lysozyme Variants Drives Amyloid Fibril Formation Por Alexander K. Buell, Anne Dhulesia, Maria F. Mossuto, Nunilo Cremades, Janet R. Kumita, Mireille Dumoulin, Mark E. Welland, Tuomas P. J. Knowles, Xavier Salvatella, Christopher M. Dobson

    Publicado em 2011
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  13. 13
    The Extracellular Chaperone Clusterin Potently Inhibits Human Lysozyme Amyloid Formation by Interacting with Prefibrillar Species

    The Extracellular Chaperone Clusterin Potently Inhibits Human Lysozyme Amyloid Formation by Interacting with Prefibrillar Species Por Janet R. Kumita, Stephen Poon, Gemma L. Caddy, Christine L. Hagan, Mireille Dumoulin, Justin J. Yerbury, Elise M. Stewart, Carol V. Robinson, Mark R. Wilson, Christopher M. Dobson

    Publicado em 2007
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  14. 14
    A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme

    A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme Por Mireille Dumoulin, A. Last, Aline Desmyter, Klaas Decanniere, Denis Canet, Göran Larsson, Andrew Spencer, David B. Archer, Jürgen Sasse, Serge Muyldermans, Lode Wyns, Christina Redfield, André Matagne, Carol V. Robinson, Christopher M. Dobson

    Publicado em 2003
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  15. 15
    Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting

    Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting Por Marie Plissonneau, Jonathan Pansieri, Laurence Heinrich-Balard, Jean‐François Morfin, Nathalie Stransky-Heilkron, Pascaline Rivory, Pierre Mowat, Mireille Dumoulin, Richard Cohen, Éric Allémann, Éva Tóth, Maria João Saraiva, Cédric Louis, Olivier Tillement, Vincent Forge, François Lux, C. Marquette

    Publicado em 2016
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  16. 16
    Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody

    Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody Por Erwin J. De Genst, Tim Guilliams, Joke Wellens, Elizabeth O’Day, Christopher A. Waudby, Sarah Meehan, Mireille Dumoulin, Shang‐Te Danny Hsu, Nunilo Cremades, Koen H. G. Verschueren, Els Pardon, Lode Wyns, Jan Steyaert, John Christodoulou, Christopher M. Dobson

    Publicado em 2010
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