Søgeresultater - Mike‐Andrew Westhoff
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Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin af Selim Corbacioglu, Mehtap Kılıç, Mike‐Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus‐Michael Debatin
Udgivet 2006Artigo -
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Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells af Joachim Bischof, Mike‐Andrew Westhoff, Johanna Wagner, Marc‐Eric Halatsch, Stephanie Trentmann, Uwe Knippschild, Christian Rainer Wirtz, Timo Burster
Udgivet 2017Revisão -
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Sequential Dosing in Chemosensitization: Targeting the PI3K/Akt/mTOR Pathway in Neuroblastoma af Mike‐Andrew Westhoff, Najmeh Faham, Daniela Marx, Lisa Nonnenmacher, Claudia Jennewein, Stefanie Enzenmüller, Patrick Gonzalez, Simone Fulda, Klaus‐Michael Debatin
Udgivet 2013Artigo -
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TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners <i>in vitro</i> and <i>in vivo</i> af Georg Karpel‐Massler, Maïmouna Bâ, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Udgivet 2015Artigo -
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Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis <i>in vitro</i> and <i>in vivo</i> af Georg Karpel‐Massler, Doruntina Ramani, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Udgivet 2016Artigo -
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TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma af Michaela Keuper, Ingrid Wernstedt Asterholm, Philipp E. Scherer, Mike‐Andrew Westhoff, Peter Möller, Klaus‐Michael Debatin, Gudrun Strauß, Martin Wabitsch, Pamela Fischer‐Posovszky
Udgivet 2013Artigo -
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The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair af Mike‐Andrew Westhoff, J. A. Kandenwein, Sabine Karl, Sri HariKrishna Vellanki, V. Braun, Adriana Eramo, Gregor Antoniadis, Klaus‐Michael Debatin, Simone Fulda
Udgivet 2009Artigo
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Cancer research
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Glioblastoma
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Programmed cell death
Cancer
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Protein kinase B
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PI3K/AKT/mTOR pathway
Signal transduction
Temozolomide
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