Resultats de la cerca - Mike‐Andrew Westhoff

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  1. 1
    Precision medicine in pediatric oncology

    Precision medicine in pediatric oncology per Stefan Burdach, Mike‐Andrew Westhoff, Maximilian Steinhauser, Klaus‐Michael Debatin

    Publicat 2018
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  2. 2
    Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

    Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin per Selim Corbacioglu, Mehtap Kılıç, Mike‐Andrew Westhoff, Dirk Reinhardt, Simone Fulda, Klaus‐Michael Debatin

    Publicat 2006
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  3. 3
    Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor– and Drug-Induced Apoptosis

    Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor– and Drug-Induced Apoptosis per Daniela Opel, Mike‐Andrew Westhoff, Ariane Bender, Veit Braun, Klaus‐Michael Debatin, Simone Fulda

    Publicat 2008
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  4. 4
    Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling

    Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling per Mike‐Andrew Westhoff, Bryan Serrels, Valerie J. Fincham, Margaret C. Frame, Neil O. Carragher

    Publicat 2004
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  5. 5
    A Novel Role for FAK as a Protease-Targeting Adaptor Protein

    A Novel Role for FAK as a Protease-Targeting Adaptor Protein per Neil O. Carragher, Mike‐Andrew Westhoff, Valerie J. Fincham, Michael D. Schaller, Margaret C. Frame

    Publicat 2003
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  6. 6
    Critical View of Novel Treatment Strategies for Glioblastoma: Failure and Success of Resistance Mechanisms by Glioblastoma Cells

    Critical View of Novel Treatment Strategies for Glioblastoma: Failure and Success of Resistance Mechanisms by Glioblastoma Cells per Timo Burster, Rebecca Traut, Zhanerke Yermekkyzy, Katja M. Mayer, Mike‐Andrew Westhoff, Joachim Bischof, Uwe Knippschild

    Publicat 2021
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  7. 7
    Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma

    Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma per Georg Karpel‐Massler, Chiaki Tsuge Ishida, Yiru Zhang, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Markus D. Siegelin

    Publicat 2017
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  8. 8
    BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma

    BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma per Chiaki Tsuge Ishida, Elena Bianchetti, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus D. Siegelin

    Publicat 2017
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  9. 9
    Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells

    Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells per Joachim Bischof, Mike‐Andrew Westhoff, Johanna Wagner, Marc‐Eric Halatsch, Stephanie Trentmann, Uwe Knippschild, Christian Rainer Wirtz, Timo Burster

    Publicat 2017
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  10. 10
    Sequential Dosing in Chemosensitization: Targeting the PI3K/Akt/mTOR Pathway in Neuroblastoma

    Sequential Dosing in Chemosensitization: Targeting the PI3K/Akt/mTOR Pathway in Neuroblastoma per Mike‐Andrew Westhoff, Najmeh Faham, Daniela Marx, Lisa Nonnenmacher, Claudia Jennewein, Stefanie Enzenmüller, Patrick Gonzalez, Simone Fulda, Klaus‐Michael Debatin

    Publicat 2013
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  11. 11
    Inhibition of HDAC1/2 Along with TRAP1 Causes Synthetic Lethality in Glioblastoma Model Systems

    Inhibition of HDAC1/2 Along with TRAP1 Causes Synthetic Lethality in Glioblastoma Model Systems per Trang Nguyen, Yiru Zhang, Enyuan Shang, Chang Shu, Catarina M. Quinzii, Mike‐Andrew Westhoff, Georg Karpel‐Massler, Markus D. Siegelin

    Publicat 2020
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  12. 12
    v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation

    v-Src-Induced Modulation of the Calpain-Calpastatin Proteolytic System Regulates Transformation per Neil O. Carragher, Mike‐Andrew Westhoff, Deborah Riley, David A. Potter, Previn Dutt, John S. Elce, Peter A. Greer, Margaret C. Frame

    Publicat 2002
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  13. 13
    TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners <i>in vitro</i> and <i>in vivo</i>

    TIC10/ONC201 synergizes with Bcl-2/Bcl-xL inhibition in glioblastoma by suppression of Mcl-1 and its binding partners <i>in vitro</i> and <i>in vivo</i> per Georg Karpel‐Massler, Maïmouna Bâ, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

    Publicat 2015
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  14. 14
    Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis <i>in vitro</i> and <i>in vivo</i>

    Metabolic reprogramming of glioblastoma cells by L-asparaginase sensitizes for apoptosis <i>in vitro</i> and <i>in vivo</i> per Georg Karpel‐Massler, Doruntina Ramani, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

    Publicat 2016
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  15. 15
    Temozolomide and Other Alkylating Agents in Glioblastoma Therapy

    Temozolomide and Other Alkylating Agents in Glioblastoma Therapy per Hannah A. Strobel, Tim Baisch, Rahel Fitzel, Katharina Schilberg, Markus D. Siegelin, Georg Karpel‐Massler, Klaus‐Michael Debatin, Mike‐Andrew Westhoff

    Publicat 2019
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  16. 16
    RIST: A potent new combination therapy for glioblastoma

    RIST: A potent new combination therapy for glioblastoma per Lisa Nonnenmacher, Mike‐Andrew Westhoff, Simone Fulda, Georg Karpel‐Massler, Marc‐Eric Halatsch, Jens Engelke, Thomas Simmet, Selim Corbacioglu, Klaus‐Michael Debatin

    Publicat 2014
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  17. 17
    A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

    A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy per Mike‐Andrew Westhoff, Georg Karpel‐Massler, Oliver Brühl, Stefanie Enzenmüller, Katia La Ferla-Brühl, Markus D. Siegelin, Lisa Nonnenmacher, Klaus‐Michael Debatin

    Publicat 2014
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  18. 18
    Inhibition of deubiquitinases primes glioblastoma cells to apoptosis <i>in vitro</i> and <i>in vivo</i>

    Inhibition of deubiquitinases primes glioblastoma cells to apoptosis <i>in vitro</i> and <i>in vivo</i> per Georg Karpel‐Massler, Matei A. Banu, Chang Shu, Marc‐Eric Halatsch, Mike‐Andrew Westhoff, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin

    Publicat 2016
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  19. 19
    TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma

    TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma per Michaela Keuper, Ingrid Wernstedt Asterholm, Philipp E. Scherer, Mike‐Andrew Westhoff, Peter Möller, Klaus‐Michael Debatin, Gudrun Strauß, Martin Wabitsch, Pamela Fischer‐Posovszky

    Publicat 2013
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  20. 20
    The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair

    The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair per Mike‐Andrew Westhoff, J. A. Kandenwein, Sabine Karl, Sri HariKrishna Vellanki, V. Braun, Adriana Eramo, Gregor Antoniadis, Klaus‐Michael Debatin, Simone Fulda

    Publicat 2009
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