檢索結果 - Michelle Kushida

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  1. 1
    Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells

    Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells 由 Graham MacLeod, Danielle Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian J. Restall, Xiaoguang Hao, Traver Hart, H. Artee Luchman, Samuel Weiss, Peter B. Dirks, Stéphane Angers

    出版 2019
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  2. 2
    Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity

    Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity 由 Mona Meyer, Jüri Reimand, Xiaoyang Lan, Renee Head, Xueming Zhu, Michelle Kushida, Jane Bayani, Jessica C. Pressey, Anath C. Lionel, Ian D. Clarke, Michael D. Cusimano, Jeremy A. Squire, Stephen W. Scherer, Mark Bernstein, Melanie A. Woodin, Gary D. Bader, Peter B. Dirks

    出版 2015
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  3. 3
    Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor

    Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor 由 Hayden Selvadurai, Erika Luis, Kinjal Desai, Xiaoyang Lan, Maria C. Vladoiu, Owen Whitley, Ciaran Galvin, Robert J. Vanner, Lilian Lee, Heather Whetstone, Michelle Kushida, Tomasz J. Nowakowski, Phedias Diamandis, Cynthia Hawkins, Gary D. Bader, Arnold R. Kriegstein, Michael D. Taylor, Peter B. Dirks

    出版 2020
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  4. 4
    SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY

    SINGLE CELL DERIVED CLONAL ANALYSIS OF HUMAN GLIOBLASTOMA LINKS FUNCTIONAL AND GENOMIC HETEROGENEITY 由 Peter B. Dirks, M D Meyer, Jüri Reimand, Xiaoyang Lan, Renee Head, Xiaoping Zhu, Michelle Kushida, Jane Bayani, Jessica C. Pressey, Anath C. Lionel, Ian D. Clarke, Michael D. Cusimano, Jeremy A. Squire, Stephen W. Scherer, Mark Bernstein, Melanie A. Woodin, Gary D. Bader

    出版 2014
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  5. 5
    OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma

    OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma 由 Kinjal Desai, Siyi Wanggou, Erika Luis, Heather Whetstone, Chun‐Ying Yu, Robert J. Vanner, Hayden Selvadurai, Lilian Lee, Jinchu Vijay, Julia E. Jaramillo, Jerry J. Fan, Paul Guilhamon, Michelle Kushida, Xuejun Li, Gregory Stein, Santosh Kesari, Benjamin D. Simons, Xi Huang, Peter B. Dirks

    出版 2025
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  6. 6
    Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells

    Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells 由 Sonam Dolma, Hayden Selvadurai, Xiaoyang Lan, Lilian Lee, Michelle Kushida, Véronique Voisin, Heather Whetstone, Milly So, Tzvi Aviv, Nicole Park, Xueming Zhu, Changjiang Xu, Renee Head, Katherine Rowland, Mark Bernstein, Ian D. Clarke, Gary D. Bader, Lea Harrington, John H. Brumell, Mike Tyers, Peter B. Dirks

    出版 2016
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  7. 7
    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

    A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression 由 Xin Chen, Siyi Wanggou, Ankur Bodalia, Min Zhu, Weifan Dong, Jerry J. Fan, Wen Yin, Hyun-Kee Min, Malini Hu, Diana Draghici, Wenkun Dou, Feng Li, Fiona J. Coutinho, Heather Whetstone, Michelle Kushida, Peter B. Dirks, Yuanquan Song, Chi‐chung Hui, Yu Sun, Lu‐Yang Wang, Xuejun Li, Xi Huang

    出版 2018
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  8. 8
    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells 由 Nicole I. Park, Paul Guilhamon, Kinjal Desai, Rochelle F. McAdam, Ellen Langille, Madlen O’Connor, Xiaoyang Lan, Heather Whetstone, Fiona J. Coutinho, Robert J. Vanner, Erick K. M. Ling, Panagiotis Prinos, Lilian Lee, Hayden Selvadurai, Gurnit Atwal, Michelle Kushida, Ian D. Clarke, Véronique Voisin, Michael D. Cusimano, Mark Bernstein, Sunit Das, Gary D. Bader, C.H. Arrowsmith, Stéphane Angers, Xi Huang, Mathieu Lupien, Peter B. Dirks

    出版 2017
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  9. 9
    High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

    High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma 由 Michael J. Johnston, Ana Nikolić, Nicoletta Ninkovic, Paul Guilhamon, Florence M.G. Cavalli, Steven Seaman, Franz J. Zemp, J. Jack Lee, Aly Abdelkareem, Katrina Ellestad, Alex Murison, Michelle Kushida, Fiona J. Coutinho, Yussanne Ma, Andrew J. Mungall, Richard A. Moore, Marco A. Marra, Michael D. Taylor, Peter B. Dirks, Trevor J. Pugh, A. Sorana Morrissy, Bradley St Croix, Douglas J. Mahoney, Mathieu Lupien, Marco Gallo

    出版 2019
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  10. 10
    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

    ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells 由 Nicole I. Park, Paul Guilhamon, Kinjal Desai, Rochelle F. McAdam, Ellen Langille, Madlen O’Connor, Xiaoyang Lan, Heather Whetstone, Fiona J. Coutinho, Robert J. Vanner, Erick K. M. Ling, Panagiotis Prinos, Lilian Lee, Hayden Selvadurai, Gurnit Atwal, Michelle Kushida, Ian D. Clarke, Véronique Voisin, Michael D. Cusimano, Mark Bernstein, Sunit Das, Gary D. Bader, C.H. Arrowsmith, Stéphane Angers, Xi Huang, Mathieu Lupien, Peter B. Dirks

    出版 2017
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  11. 11
    Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma

    Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma 由 Robert J. Vanner, Marc Remke, Marco Gallo, Hayden Selvadurai, Fiona J. Coutinho, Lilian Lee, Michelle Kushida, Renee Head, A. Sorana Morrissy, Xueming Zhu, Tzvi Aviv, Véronique Voisin, Ian D. Clarke, Yisu Li, Andrew J. Mungall, Richard A. Moore, Yussanne Ma, Steven J.M. Jones, Marco A. Marra, David Malkin, Paul A. Northcott, Marcel Kool, Stefan M. Pfister, Gary D. Bader, Konrad Hochedlinger, Andrey Korshunov, Michael D. Taylor, Peter B. Dirks

    出版 2014
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  12. 12
    Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

    Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival 由 Paul Guilhamon, Charles Chesnelong, Michelle Kushida, Ana Nikolić, Divya Singhal, Graham MacLeod, Seyed Ali Madani Tonekaboni, Florence M.G. Cavalli, Christopher Arlidge, Nishani Rajakulendran, Naghmeh Rastegar, Xiaoguang Hao, Rozina Hassam, Laura J. Smith, Heather Whetstone, Fiona J. Coutinho, Bettina Nadorp, Katrina Ellestad, H. Artee Luchman, Jennifer A. Chan, Molly S. Shoichet, Michael D. Taylor, Benjamin Haibe‐Kains, Samuel Weiss, Stéphane Angers, Marco Gallo, Peter B. Dirks, Mathieu Lupien

    出版 2021
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  13. 13
    MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin

    MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin 由 Marco Gallo, Fiona J. Coutinho, Robert J. Vanner, Tenzin Gayden, Stephen C. Mack, Alex Murison, Marc Remke, Li Ren, Naoya Takayama, Kinjal Desai, Lilian Lee, Xiaoyang Lan, Nicole I. Park, Dalia Baršytė-Lovejoy, David Smil, Dominik Sturm, Michelle Kushida, Renee Head, Michael D. Cusimano, Mark Bernstein, Ian D. Clarke, John E. Dick, Stefan M. Pfister, Jeremy N. Rich, C.H. Arrowsmith, Michael D. Taylor, Nada Jabado, David P. Bazett‐Jones, Mathieu Lupien, Peter B. Dirks

    出版 2015
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  14. 14
    GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer

    GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer 由 Qin Wu, Wail Ba-Alawi, Geneviève Deblois, Jennifer Cruickshank, Shili Duan, Evelyne Lima‐Fernandes, Jillian Haight, Seyed Ali Madani Tonekaboni, Anne-Marie Fortier, Hellen Kuasne, Trevor D. McKee, Hassan Mahmoud, Michelle Kushida, Sarina Cameron, Nergiz Doğan, Wenjun Chen, Yan Nie, Lan-Xin Zhang, Ravi N. Vellanki, Stanley Zhou, Panagiotis Prinos, Bradly G. Wouters, Peter B. Dirks, Susan J. Done, Morag Park, David W. Cescon, Benjamin Haibe‐Kains, Mathieu Lupien, C.H. Arrowsmith

    出版 2020
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  15. 15
    PRMT5 is required for full-length<i>HTT</i>expression by repressing multiple proximal intronic polyadenylation sites

    PRMT5 is required for full-length<i>HTT</i>expression by repressing multiple proximal intronic polyadenylation sites 由 Mona Alqazzaz, Felipe E. Ciamponi, Jolene Caifeng Ho, Maxim I. Maron, Manisha Yadav, Aiden M. Sababi, Graham MacLeod, Moloud Ahmadi, Garrett Bullivant, Vincent Tano, Sarah R. Langley, María Sánchez‐Osuna, Patty Sachamitr, Michelle Kushida, Laura M. Richards, Costanza Ferrari Bardile, Mahmoud A. Pouladi, Trevor J. Pugh, Mike Tyers, Stéphane Angers, Peter B. Dirks, Gary D. Bader, Katlin B. Massirer, Dalia Baršytė-Lovejoy, David Shechter, Rachel Harding, C.H. Arrowsmith, Panagiotis Prinos

    出版 2024
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  16. 16
    PRMT5 promotes full-length <i>HTT</i> expression by repressing multiple proximal intronic polyadenylation sites

    PRMT5 promotes full-length <i>HTT</i> expression by repressing multiple proximal intronic polyadenylation sites 由 Manisha Yadav, Mona Alqazzaz, Felipe E. Ciamponi, Jolene Caifeng Ho, Maxim I. Maron, Aiden M. Sababi, Graham MacLeod, Moloud Ahmadi, Garrett Bullivant, Vincent Tano, Sarah R. Langley, María Sánchez‐Osuna, Patty Sachamitr, Michelle Kushida, Costanza Ferrari Bardile, Mahmoud A. Pouladi, Rebecca Kurtz, Laura M. Richards, Trevor J. Pugh, Mike Tyers, Stéphane Angers, Peter Dirks, Gary D. Bader, Ray Truant, Katlin B. Massirer, Dalia Baršytė-Lovejoy, David Shechter, Rachel Harding, C.H. Arrowsmith, Panagiotis Prinos

    出版 2025
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  17. 17
    Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

    Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy 由 Xiaoyang Lan, David J. Jörg, Florence M.G. Cavalli, Laura M. Richards, Long Nguyen, Robert J. Vanner, Paul Guilhamon, Lilian Lee, Michelle Kushida, Davide Pellacani, Nicole I. Park, Fiona J. Coutinho, Heather Whetstone, Hayden Selvadurai, Clare Che, Betty Luu, Annaïck Carles, Michelle Moksa, Naghmeh Rastegar, Renee Head, Sonam Dolma, Panagiotis Prinos, Michael D. Cusimano, Sunit Das, Mark Bernstein, C.H. Arrowsmith, Andrew J. Mungall, Richard A. Moore, Yussanne Ma, Marco Gallo, Mathieu Lupien, Trevor J. Pugh, Michael D. Taylor, Martin Hirst, Connie J. Eaves, Benjamin D. Simons, Peter B. Dirks

    出版 2017
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  18. 18
    PRMT5 inhibition disrupts splicing and stemness in glioblastoma

    PRMT5 inhibition disrupts splicing and stemness in glioblastoma 由 Patty Sachamitr, Jolene Caifeng Ho, Felipe E. Ciamponi, Wail Ba-Alawi, Fiona J. Coutinho, Paul Guilhamon, Michelle Kushida, Florence M.G. Cavalli, Lilian Lee, Naghmeh Rastegar, Victoria Vu, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Evgeny Kanshin, Heather Whetstone, Mathieu Durand, P Thibault, Kirsten Hart, Maria Mangos, Joseph Veyhl, Wenjun Chen, Nhat Tran, Bang-Chi Duong, Ahmed Aman, Xinghui Che, Xiaoyang Lan, Owen Whitley, Olga Zaslaver, Dalia Baršytė-Lovejoy, Laura M. Richards, Ian J. Restall, Amy A. Caudy, Hannes Röst, Zahid Bonday, Mark Bernstein, Sunit Das, Michael D. Cusimano, Julian Spears, Gary D. Bader, Trevor J. Pugh, Mike Tyers, Mathieu Lupien, Benjamin Haibe‐Kains, H. Artee Luchman, Samuel Weiss, Katlin B. Massirer, Panagiotis Prinos, C.H. Arrowsmith, Peter B. Dirks

    出版 2021
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