Search Results - Michele Cea

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  1. 1
    Nutrients in the Prevention of Alzheimer’s Disease

    Nutrients in the Prevention of Alzheimer’s Disease by Anna Laura Cremonini, Irene Caffa, Michele Cea, Alessio Nencioni, Patrizio Odetti, Fiammetta Monacelli

    Published 2019
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  2. 2
    Autophagy in blood cancers: biological role and therapeutic implications

    Autophagy in blood cancers: biological role and therapeutic implications by Alessio Nencioni, Michele Cea, Fabrizio Montecucco, Valter D. Longo, Franco Patrone, Angelo Michele Carella, Tessa L. Holyoake, G. Vignir Helgason

    Published 2013
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  3. 3
    Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition

    Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition by Irene Caffa, Vito D’Agostino, Patrizia Damonte, Debora Soncini, Michele Cea, Fiammetta Monacelli, Patrizio Odetti, Alberto Ballestrero, Alessandro Provenzani, Valter D. Longo, Alessio Nencioni

    Published 2015
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  4. 4
    SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells

    SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells by Giovanna Sociali, Alessia Grozio, Irene Caffa, Susanne Schuster, Pamela Becherini, Patrizia Damonte, Laura Sturla, Chiara Fresia, Mario Passalacqua, Francesca Mazzola, Nadia Raffaelli, Antje Garten, Wieland Kieß, Michele Cea, Alessio Nencioni, Santina Bruzzone

    Published 2018
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  5. 5
    Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity

    Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity by Antonia Cagnetta, Michele Cea, Teresa Calimeri, Chirag Acharya, Mariateresa Fulciniti, Yu‐Tzu Tai, Teru Hideshima, Dharminder Chauhan, Mike Zhong, Franco Patrone, Alessio Nencioni, Marco Gobbi, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson

    Published 2013
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  6. 6
    APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment

    APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment by Yu‐Tzu Tai, Chirag Acharya, Gang An, Michele Moschetta, Mike Zhong, Xiaoyan Feng, Michele Cea, Antonia Cagnetta, Kenneth Wen, Hans van Eenennaam, Andrea van Elsas, Lugui Qiu, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson

    Published 2016
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  7. 7
    The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses

    The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses by Inga Bauer, Alessia Grozio, Denise Lasigliè, Giovanna Basile, Laura Sturla, Mirko Magnone, Giovanna Sociali, Debora Soncini, Irene Caffa, Alessandro Poggi, Gabriele Zoppoli, Michele Cea, Georg Feldmann, Raúl Mostoslavsky, Alberto Ballestrero, Franco Patrone, Santina Bruzzone, Alessio Nencioni

    Published 2012
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  8. 8
    Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair

    Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair by Francesco Piacente, Irene Caffa, Silvia Ravera, Giovanna Sociali, Mario Passalacqua, Valerio Gaetano Vellone, Pamela Becherini, Daniele Reverberi, Fiammetta Monacelli, Alberto Ballestrero, Patrizio Odetti, Antonia Cagnetta, Michele Cea, Aimable Nahimana, Michel A. Duchosal, Santina Bruzzone, Alessio Nencioni

    Published 2017
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  9. 9
    Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model

    Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model by Giovanna Sociali, Mirko Magnone, Silvia Ravera, Patrizia Damonte, Tiziana Vigliarolo, Maria von Holtey, Valerio Gaetano Vellone, Enrico Millo, Irene Caffa, Michele Cea, Marco Parenti, Alberto Del Río, Maximilien Murone, Raúl Mostoslavsky, Alessia Grozio, Alessio Nencioni, Santina Bruzzone

    Published 2017
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  10. 10
    Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

    Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE by Santina Bruzzone, Floriana Fruscione, Sara Morando, T Ferrando, Alessandro Poggi, Anna Garuti, Agustina D’Urso, Martina Selmo, Federica Benvenuto, Michele Cea, Gabriele Zoppoli, Eva Morán, Debora Soncini, Alberto Ballestrero, Bernard Sordat, Franco Patrone, Raúl Mostoslavsky, Antonio Uccelli, Alessio Nencioni

    Published 2009
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  11. 11
    Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

    Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma by Yu‐Tzu Tai, Patrick A. Mayes, Chirag Acharya, Mike Zhong, Michele Cea, Antonia Cagnetta, Jenny Craigen, John Yates, Louise Gliddon, William Fieles, Bao Hoang, James Tunstead, Amanda L. Christie, Andrew L. Kung, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson

    Published 2014
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  12. 12
    The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival

    The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival by Hiroto Ohguchi, Teru Hideshima, Manoj Bhasin, Güllü Görgün, Loredana Santo, Michele Cea, Mehmet Samur, Naoya Mimura, Rikio Suzuki, Yu Tai, Ruben D. Carrasco, Noopur Raje, Paul G. Richardson, Nikhil C. Munshi, Hideo Harigae, Takaomi Sanda, Juro Sakai, Kenneth C. Anderson

    Published 2016
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  13. 13
    SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice

    SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice by Pamela Becherini, Irene Caffa, Francesco Piacente, Patrizia Damonte, Valerio Gaetano Vellone, Mario Passalacqua, Andrea Benzi, Tommaso Bonfiglio, Daniele Reverberi, A. Khalifa, Moustafa Ghanem, Ana Guijarro, Luca Tagliafico, Marzia Sucameli, A Persia, Fiammetta Monacelli, Michele Cea, Santina Bruzzone, Silvia Ravera, Alessio Nencioni

    Published 2021
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  14. 14
    Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition

    Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition by Michele Cea, Antonia Cagnetta, Mariateresa Fulciniti, Yu‐Tzu Tai, Teru Hideshima, Dharminder Chauhan, Aldo M. Roccaro, Antonio Sacco, Teresa Calimeri, Francesca Cottini, Jana Jakubı́ková, Sun‐Young Kong, Franco Patrone, Alessio Nencioni, Marco Gobbi, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson

    Published 2012
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  15. 15
    Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity

    Nicotinamide Phosphoribosyltransferase Promotes Epithelial-to-Mesenchymal Transition as a Soluble Factor Independent of Its Enzymatic Activity by Debora Soncini, Irene Caffa, Gabriele Zoppoli, Michele Cea, Antonia Cagnetta, Mario Passalacqua, Luca Mastracci, Silvia Boero, Fabrizio Montecucco, Giovanna Sociali, Denise Lasigliè, Patrizia Damonte, Alessia Grozio, Elena Mannino, Alessandro Poggi, Vito D’Agostino, Fiammetta Monacelli, Alessandro Provenzani, Patrizio Odetti, Alberto Ballestrero, Santina Bruzzone, Alessio Nencioni

    Published 2014
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  16. 16
    Synergistic Interactions between HDAC and Sirtuin Inhibitors in Human Leukemia Cells

    Synergistic Interactions between HDAC and Sirtuin Inhibitors in Human Leukemia Cells by Michele Cea, Debora Soncini, Floriana Fruscione, Lizzia Raffaghello, Anna Garuti, Laura Emionite, Eva Morán, Mirko Magnone, Gabriele Zoppoli, Daniele Reverberi, Irene Caffa, Annalisa Salis, Antonia Cagnetta, Micaela Bergamaschi, Salvatore Casciaro, Ivana Pierri, Gianluca Damonte, Filippo Ansaldi, Marco Gobbi, Vito Pistoia, Alberto Ballestrero, Franco Patrone, Santina Bruzzone, Alessio Nencioni

    Published 2011
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  17. 17
    Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells’ vulnerability to DNA-damaging agents

    Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells’ vulnerability to DNA-damaging agents by Antonia Cagnetta, Debora Soncini, Stefania Orecchioni, Giovanna Talarico, Paola Minetto, Fabio Guolo, Veronica Retali, Nicoletta Colombo, Enrico Carminati, Marino Clavio, Maurizio Miglino, Micaela Bergamaschi, Aimable Nahimana, Michel A. Duchosal, Katia Todoerti, Antonino Neri, Mario Passalacqua, Santina Bruzzone, Alessio Nencioni, Francesco Bertolini, Marco Gobbi, Roberto M. Lemoli, Michele Cea

    Published 2017
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  18. 18
    CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation

    CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation by Aldo M. Roccaro, Yuji Mishima, Antonio Sacco, Michele Moschetta, Yu‐Tzu Tai, Jiantao Shi, Yong Zhang, Michaela R. Reagan, Daisy Huynh, Yawara Kawano, İlyas Şahin, Marco Chiarini, Salomon Manier, Michele Cea, Yosra Aljawai, Siobhan Glavey, Elizabeth A. Morgan, Chin Pan, Franziska Michor, Pina M. Cardarelli, Michelle Kuhne, Irene M. Ghobrial

    Published 2015
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  19. 19
    Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

    Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells by Michele Cea, Antonia Cagnetta, Sophia Adamia, Chirag Acharya, Yu‐Tzu Tai, Mariateresa Fulciniti, Hiroto Ohguchi, Aditya Munshi, Prakrati Acharya, Manoj Bhasin, Lei Zhong, Ruben D. Carrasco, Fiammetta Monacelli, Alberto Ballestrero, Paul G. Richardson, Marco Gobbi, Roberto M. Lemoli, Nikhil C. Munshi, Teru Hideshima, Alessio Nencioni, Dharminder Chauhan, Kenneth C. Anderson

    Published 2015
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  20. 20
    Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma

    Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma by Yu‐Tzu Tai, Betty Chang, Sun‐Young Kong, Mariateresa Fulciniti, Guang Yang, Yolanda Calle, Yiguo Hu, Jianhong Lin, Jianjun Zhao, Antonia Cagnetta, Michele Cea, Michael Sellitto, Mike Zhong, Qiuju Wang, Chirag Acharya, Daniel R. Carrasco, Joseph J. Buggy, Laurence Elias, Steven P. Treon, William Matsui, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson

    Published 2012
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