Výsledky vyhledávání - Michaeline Hebron

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  1. 1
    Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance

    Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance Autor Michaeline Hebron, Irina Lonskaya, Charbel Moussa

    Vydáno 2013
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  2. 2
    Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of -synuclein in Parkinson's disease models

    Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of -synuclein in Parkinson's disease models Autor Michaeline Hebron, Irina Lonskaya, Charbel Moussa

    Vydáno 2013
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  3. 3
    Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance

    Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance Autor Irina Lonskaya, Nicole M. Desforges, Michaeline Hebron, Charbel Moussa

    Vydáno 2013
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  4. 4
    Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies

    Ubiquitin specific protease-13 independently regulates parkin ubiquitination and alpha-synuclein clearance in alpha-synucleinopathies Autor Xiaoguang Liu, Michaeline Hebron, Wangke Shi, Irina Lonskaya, Charbel Moussa

    Vydáno 2018
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  5. 5
    Tyrosine kinase inhibition increases functional parkin‐ <scp>B</scp> eclin‐1 interaction and enhances amyloid clearance and cognitive performance

    Tyrosine kinase inhibition increases functional parkin‐ <scp>B</scp> eclin‐1 interaction and enhances amyloid clearance and cognitive performance Autor Irina Lonskaya, Michaeline Hebron, Nicole M. Desforges, Alexander Franjie, Charbel Moussa

    Vydáno 2013
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  6. 6
    Tau deletion impairs intracellular β-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models

    Tau deletion impairs intracellular β-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models Autor Irina Lonskaya, Michaeline Hebron, Wenqiang Chen, Joel B. Schachter, Charbel Moussa

    Vydáno 2014
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  7. 7
    Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-Synucleinopathy

    Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-Synucleinopathy Autor Michaeline Hebron, Irina Lonskaya, Paul Olopade, S. Selby, Fernando Pagán, Charbel Moussa

    Vydáno 2014
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  8. 8
    Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer’s Disease

    Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer’s Disease Autor Xiaoguang Liu, Sean Baxley, Michaeline Hebron, Raymond Scott Turner, Charbel Moussa

    Vydáno 2025
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  9. 9
    Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance

    Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance Autor Irina Lonskaya, Michaeline Hebron, Nicole M. Desforges, Joel B. Schachter, Charbel Moussa

    Vydáno 2013
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  10. 10
    Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease

    Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease Autor Irina Lonskaya, Michaeline Hebron, Norah K. Algarzae, Nicole M. Desforges, Charbel Moussa

    Vydáno 2012
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  11. 11
    Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

    Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease Autor Charbel Moussa, Michaeline Hebron, Xu Huang, Jaeil Ahn, Robert A. Rissman, Paul Aisen, Raymond Scott Turner

    Vydáno 2017
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  12. 12
    Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease

    Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease Autor Max Stevenson, Rency S. Varghese, Michaeline Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, Raymond Scott Turner, Charbel Moussa

    Vydáno 2023
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  13. 13
    Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6)

    Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6) Autor Michaeline Hebron, Irina Lonskaya, Kaydee Sharpe, Puwakdandawe P.K. Weerasinghe, Norah K. Algarzae, Ashot R. Shekoyan, Charbel Moussa

    Vydáno 2012
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  14. 14
    Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration

    Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration Autor Alan J. Fowler, Michaeline Hebron, Alexander A. Missner, Ruochong Wang, Xiaokong Gao, Bahjat T. Kurd-Misto, Xiaoguang Liu, Charbel Moussa

    Vydáno 2019
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  15. 15
    Long‐Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease

    Long‐Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease Autor Fernando Pagán, Barbara Wilmarth, Yasar Torres‐Yaghi, Michaeline Hebron, Sanjana Mulki, Dalila Ferrante, Sara Matar, Jaeil Ahn, Charbel Moussa

    Vydáno 2020
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  16. 16
    Tyrosine kinase inhibition reverses <scp>TDP</scp>‐43 effects on synaptic protein expression, astrocytic function and amino acid dis‐homeostasis

    Tyrosine kinase inhibition reverses <scp>TDP</scp>‐43 effects on synaptic protein expression, astrocytic function and amino acid dis‐homeostasis Autor Lanier Heyburn, Michaeline Hebron, Jacqueline Smith, Charisse N. Winston, John P. Bechara, Zhaoxia Li, Irina Lonskaya, Mark P. Burns, Brent T. Harris, Charbel Moussa

    Vydáno 2016
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  17. 17
    Nilotinib Effects in Parkinson’s disease and Dementia with Lewy bodies

    Nilotinib Effects in Parkinson’s disease and Dementia with Lewy bodies Autor Fernando Pagán, Michaeline Hebron, Ellen Valadez, Yasar Torres‐Yaghi, Xu Huang, Reversa Mills, Barbara Wilmarth, Hellen Howard, Connell Dunn, Alexis Carlson, Abigail Lawler, Sean Rogers, Ramsey Falconer, Jaeil Ahn, Zhaoxia Li, Charbel Moussa

    Vydáno 2016
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  18. 18
    Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease

    Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson's disease Autor Fernando Pagán, Michaeline Hebron, Barbara Wilmarth, Yasar Torres‐Yaghi, Abigail Lawler, Elizabeth Mundel, Nadia Yusuf, Nathan Starr, Joy Arellano, Helen Howard, Margo A. Peyton, Sara Matar, Xiaoguang Liu, Alan J. Fowler, Sorell L. Schwartz, Jaeil Ahn, Charbel Moussa

    Vydáno 2019
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  19. 19
    Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease

    Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease Autor Fernando Pagán, Michaeline Hebron, Barbara Wilmarth, Yasar Torres‐Yaghi, Abigail Lawler, Elizabeth Mundel, Nadia Yusuf, Nathan Starr, Muhammad Anjum, Joy Arellano, Helen Howard, Wangke Shi, Sanjana Mulki, Tarick Kurd-Misto, Sara Matar, Xiaoguang Liu, Jaeil Ahn, Charbel Moussa

    Vydáno 2019
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  20. 20
    Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease

    Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease Autor Raymond Scott Turner, Michaeline Hebron, Abigail Lawler, Elizabeth Mundel, Nadia Yusuf, J. Nathan Starr, Muhammad Anjum, Fernando Pagán, Yasar Torres‐Yaghi, Wangke Shi, Sanjana Mulki, Dalila Ferrante, Sara Matar, Xiaoguang Liu, Giuseppe Esposito, Frank E. Berkowitz, Xiong Jiang, Jaeil Ahn, Charbel Moussa

    Vydáno 2020
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